HK1203850A1 - 光敏劑和殼聚糖的偶聯物及其應用 - Google Patents

光敏劑和殼聚糖的偶聯物及其應用

Info

Publication number
HK1203850A1
HK1203850A1 HK15104699.9A HK15104699A HK1203850A1 HK 1203850 A1 HK1203850 A1 HK 1203850A1 HK 15104699 A HK15104699 A HK 15104699A HK 1203850 A1 HK1203850 A1 HK 1203850A1
Authority
HK
Hong Kong
Prior art keywords
photosensitiser
chitosan
conjugate
Prior art date
Application number
HK15104699.9A
Other languages
English (en)
Inventor
Kristian Berg
Anders Hgset
Mr Msson
Vivek S Gaware
Original Assignee
Pci Biotech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pci Biotech As filed Critical Pci Biotech As
Publication of HK1203850A1 publication Critical patent/HK1203850A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK15104699.9A 2012-05-15 2015-05-18 光敏劑和殼聚糖的偶聯物及其應用 HK1203850A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1208548.6A GB201208548D0 (en) 2012-05-15 2012-05-15 Compound and method
PCT/EP2013/059968 WO2013189663A1 (en) 2012-05-15 2013-05-14 Conjugate of a photosensitiser and chitosan and uses thereof

Publications (1)

Publication Number Publication Date
HK1203850A1 true HK1203850A1 (zh) 2015-11-06

Family

ID=46458880

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15104699.9A HK1203850A1 (zh) 2012-05-15 2015-05-18 光敏劑和殼聚糖的偶聯物及其應用

Country Status (24)

Country Link
US (1) US9901636B2 (zh)
EP (1) EP2849791B1 (zh)
JP (1) JP6456284B2 (zh)
KR (2) KR20150013803A (zh)
CN (1) CN104780941B (zh)
AU (1) AU2013279748B2 (zh)
BR (1) BR112014028315B1 (zh)
CA (1) CA2873259C (zh)
DK (1) DK2849791T3 (zh)
ES (1) ES2682762T3 (zh)
GB (1) GB201208548D0 (zh)
HK (1) HK1203850A1 (zh)
HR (1) HRP20181276T1 (zh)
HU (1) HUE039725T2 (zh)
IN (1) IN2014DN09418A (zh)
MX (1) MX362237B (zh)
NZ (1) NZ630582A (zh)
PL (1) PL2849791T3 (zh)
PT (1) PT2849791T (zh)
RU (1) RU2675830C2 (zh)
SG (1) SG11201407603YA (zh)
SI (1) SI2849791T1 (zh)
WO (1) WO2013189663A1 (zh)
ZA (1) ZA201408406B (zh)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9905911D0 (en) 1999-03-15 1999-05-05 Photocure As Method
US10973896B2 (en) 2014-04-11 2021-04-13 Pci Biotech As Treatment or prevention of melanoma using photochemical internalization of a melanoma antigen
NZ729408A (en) * 2014-08-28 2021-12-24 Pci Biotech As A method of photochemical internalization (pci) utilizing a antigenic molecule, a photosensitizing agent, and a cytokine
CN104650259A (zh) * 2015-01-23 2015-05-27 广西大学 一种纳米孔壳聚糖四(4-磺酸基苯基)金属卟啉微球及其制备方法和使用方法
GB201503776D0 (en) 2015-03-05 2015-04-22 Pci Biotech As Compound and method
GB201511159D0 (en) 2015-06-24 2015-08-05 Univ Nottingham Controlled cell delivery vehicle and treatment of tumours
EP3433422B1 (en) 2016-03-22 2020-11-18 Åbo Akademi University Polysaccharide derivatives as optical brightening agents
KR20190013289A (ko) * 2017-08-01 2019-02-11 순천대학교 산학협력단 수용성 키토산을 포함하는 나노광증감제
GB201801169D0 (en) * 2018-01-24 2018-03-07 Pci Biotech As Method
CN108892743A (zh) * 2018-05-28 2018-11-27 南京工业大学 用于光动力抗菌的纳米光敏剂，其制备方法及应用
GB202101726D0 (en) 2021-02-08 2021-03-24 Pci Biotech As Method
CN115399328B (zh) * 2021-05-27 2024-03-22 中国科学院化学研究所 一种多糖基杀菌材料及其制备方法和应用
GB202115451D0 (en) 2021-10-27 2021-12-08 Pci Biotech As Method

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NO180167C (no) * 1994-09-08 1997-02-26 Photocure As Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol
GB9905911D0 (en) * 1999-03-15 1999-05-05 Photocure As Method
US20020022032A1 (en) 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
GB0018527D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Composition
JP2002241307A (ja) * 2001-02-19 2002-08-28 Yasuhiko Tabata 光増感剤を含有する超音波治療用活性酸素発生剤
GB0121023D0 (en) 2001-08-30 2001-10-24 Norwegian Radium Hospital Res Compound
GB0415663D0 (en) 2004-07-13 2004-08-18 Psimei Pharmaceuticals Plc Compound
EP1888115A2 (en) 2005-05-16 2008-02-20 Universite De Geneve Compounds for photochemotherapy
JP4287411B2 (ja) * 2005-07-01 2009-07-01 株式会社東芝 仮想メモリシステムおよび仮想記憶方法
CN101024087A (zh) * 2007-03-28 2007-08-29 长沙理工大学 壳聚糖－多肽－卟啉纳米药物载体及其制备和应用
KR101035269B1 (ko) * 2007-04-23 2011-05-26 한국과학기술연구원 고분자 유도체-광감작제 복합체를 이용한 새로운 광역학치료제
KR20090047872A (ko) 2007-11-08 2009-05-13 인제대학교 산학협력단 신규 카보하이드레이트 복합 클로린 화합물 및 이의제조방법
WO2009077908A1 (en) 2007-12-14 2009-06-25 University Of Lausanne Colloidal particle comprising multivalent cyclic anions
KR101076717B1 (ko) 2008-11-07 2011-10-26 재단법인대구경북과학기술원 광역학 치료용 나노구조체 및 그 제조방법
US20100129432A1 (en) 2008-11-25 2010-05-27 Taipei Medical University Microorganism-killing combination
CN101977608A (zh) 2009-04-29 2011-02-16 多异亚德韩国株式会社 含有二氢卟酚e6-叶酸共轭化合物和壳聚糖的用于癌症治疗的药物组合物
KR100918811B1 (ko) 2009-04-29 2009-09-25 다이아텍코리아 주식회사 클로린 ｅ６-엽산 결합 화합물 및 키토산을 함유하는 암 치료용 약학적 조성물
JP5662431B2 (ja) * 2009-06-12 2015-01-28 エラスムス・ユニヴァーシティ・メディカル・センター・ロッテルダム 癌の光線力学療法のための標的化されたナノフォトメディスン
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KR101228106B1 (ko) 2010-01-21 2013-02-01 광주과학기술원 피부투과도, 세포유입 및 종양전달성이 증가된 나노운반체
KR101250150B1 (ko) * 2010-10-29 2013-04-04 가톨릭대학교 산학협력단 광역학치료를 위한 고분자-광응답제 접합체 및 이의 제조방법

Also Published As

Publication number Publication date
CA2873259C (en) 2021-08-03
KR20150013803A (ko) 2015-02-05
MX362237B (es) 2019-01-09
SG11201407603YA (en) 2014-12-30
WO2013189663A1 (en) 2013-12-27
EP2849791A1 (en) 2015-03-25
HUE039725T2 (hu) 2019-01-28
NZ630582A (en) 2017-02-24
KR102269861B1 (ko) 2021-06-28
PL2849791T3 (pl) 2019-03-29
CN104780941A (zh) 2015-07-15
MX2014013516A (es) 2015-11-13
PT2849791T (pt) 2018-10-04
JP6456284B2 (ja) 2019-01-23
KR20200085380A (ko) 2020-07-14
US9901636B2 (en) 2018-02-27
HRP20181276T1 (hr) 2018-11-16
AU2013279748A1 (en) 2014-11-20
EP2849791B1 (en) 2018-07-04
ZA201408406B (en) 2016-02-24
AU2013279748B2 (en) 2018-08-02
RU2014150569A (ru) 2016-07-10
BR112014028315B1 (pt) 2022-02-22
BR112014028315A2 (pt) 2017-10-24
US20150202293A1 (en) 2015-07-23
GB201208548D0 (en) 2012-06-27
CN104780941B (zh) 2019-01-15
ES2682762T3 (es) 2018-09-21
RU2675830C2 (ru) 2018-12-25
CA2873259A1 (en) 2013-12-27
JP2015516496A (ja) 2015-06-11
IN2014DN09418A (zh) 2015-07-17
SI2849791T1 (sl) 2018-10-30
DK2849791T3 (en) 2018-08-13

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230511