HK1200815A1 - 作為磷酸二酯酶抑制劑的 三唑並吡啶類化合物及其應用 - Google Patents

作為磷酸二酯酶抑制劑的 三唑並吡啶類化合物及其應用

Info

Publication number
HK1200815A1
HK1200815A1 HK15101191.8A HK15101191A HK1200815A1 HK 1200815 A1 HK1200815 A1 HK 1200815A1 HK 15101191 A HK15101191 A HK 15101191A HK 1200815 A1 HK1200815 A1 HK 1200815A1
Authority
HK
Hong Kong
Prior art keywords
triazolopyridines
phospodiesterase inhibitors
phospodiesterase
inhibitors
Prior art date
Application number
HK15101191.8A
Other languages
English (en)
Inventor
Simon Feldbk Nielsen
Jens Christian Hjland Larsen
Original Assignee
Leo Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharma As filed Critical Leo Pharma As
Publication of HK1200815A1 publication Critical patent/HK1200815A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK15101191.8A 2011-12-21 2015-02-04 作為磷酸二酯酶抑制劑的 三唑並吡啶類化合物及其應用 HK1200815A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161578677P 2011-12-21 2011-12-21
US201261666430P 2012-06-29 2012-06-29
PCT/EP2012/076191 WO2013092739A1 (en) 2011-12-21 2012-12-19 [1,2,4]triazolopyridines and their use as phospodiesterase inhibitors

Publications (1)

Publication Number Publication Date
HK1200815A1 true HK1200815A1 (zh) 2015-08-14

Family

ID=47429831

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15101191.8A HK1200815A1 (zh) 2011-12-21 2015-02-04 作為磷酸二酯酶抑制劑的 三唑並吡啶類化合物及其應用

Country Status (20)

Country Link
US (2) US8940761B2 (zh)
EP (1) EP2794603B1 (zh)
JP (1) JP6138150B2 (zh)
KR (1) KR20140105598A (zh)
CN (1) CN104011048B (zh)
AU (1) AU2012357106A1 (zh)
BR (1) BR112014014802A2 (zh)
CA (1) CA2858123A1 (zh)
ES (1) ES2583478T3 (zh)
HK (1) HK1200815A1 (zh)
IL (1) IL232712A (zh)
MX (1) MX2014006812A (zh)
PL (1) PL2794603T3 (zh)
PT (1) PT2794603T (zh)
RU (1) RU2630699C2 (zh)
SG (1) SG11201402424PA (zh)
TW (1) TW201331202A (zh)
UA (1) UA111520C2 (zh)
WO (1) WO2013092739A1 (zh)
ZA (1) ZA201403649B (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8980905B2 (en) * 2010-06-24 2015-03-17 Leo Pharma A/S Benzodioxole or benzodioxepine heterocyclic compounds as phosphodiesterase inhibitors
WO2014206903A1 (en) * 2013-06-25 2014-12-31 Leo Pharma A/S METHODS FOR THE PREPARATION OF SUBSTITUTED [1,2,4]TRIAZOLO[1,5-a]PYRIDINES
US11292799B2 (en) * 2017-12-15 2022-04-05 UNION therapeutics A/S Substituted azetidine dihydrothienopyrimidines and their use as phosphodiesterase inhibitors
EP3724196B9 (en) 2017-12-15 2023-03-22 UNION therapeutics A/S Substituted azetidine dihydrothienopyridines and their use as phosphodiesterase inhibitors
JP7068219B2 (ja) 2019-03-18 2022-05-16 トヨタ自動車株式会社 排気再循環バルブ暖機装置

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1163493C (zh) 1995-05-19 2004-08-25 协和发酵工业株式会社 含氧杂环化合物
EP0943613A4 (en) 1996-11-19 2002-07-10 Kyowa Hakko Kogyo Kk HETEROCYCLIC COMPOUNDS CONTAINING OXYGEN
US6514989B1 (en) * 2001-07-20 2003-02-04 Hoffmann-La Roche Inc. Aromatic and heteroaromatic substituted 1,2,4-triazolo pyridine derivatives
US20080248958A1 (en) * 2007-04-05 2008-10-09 Hollenbach Andrew D System for pulling out regulatory elements in vitro
WO2008125111A1 (en) 2007-04-16 2008-10-23 Leo Pharma A/S Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases
MX2011006428A (es) * 2008-12-19 2011-07-28 Leo Pharma As Triazolopiridinas como inhibidores de fosfodiesterasa para tratamiento de enfermedades dermicas.
EP2200394B1 (en) * 2008-12-19 2012-08-15 Rtx A/S Cell for self-configuring wireless communication network
WO2011134468A1 (en) * 2010-04-28 2011-11-03 Leo Pharma A/S Biaryl phosphodiesterase inhibitors

Also Published As

Publication number Publication date
JP2015502381A (ja) 2015-01-22
WO2013092739A1 (en) 2013-06-27
US20140329853A1 (en) 2014-11-06
CA2858123A1 (en) 2013-06-27
ES2583478T3 (es) 2016-09-21
EP2794603B1 (en) 2016-06-15
US8940761B2 (en) 2015-01-27
IL232712A (en) 2016-06-30
RU2630699C2 (ru) 2017-09-12
US9181248B2 (en) 2015-11-10
UA111520C2 (uk) 2016-05-10
NZ625849A (en) 2016-06-24
RU2014129514A (ru) 2016-02-10
IL232712A0 (en) 2014-08-03
US20150105420A1 (en) 2015-04-16
TW201331202A (zh) 2013-08-01
PT2794603T (pt) 2016-07-26
KR20140105598A (ko) 2014-09-01
SG11201402424PA (en) 2014-09-26
JP6138150B2 (ja) 2017-05-31
CN104011048A (zh) 2014-08-27
MX2014006812A (es) 2014-10-13
BR112014014802A2 (pt) 2017-06-13
EP2794603A1 (en) 2014-10-29
ZA201403649B (en) 2016-05-25
CN104011048B (zh) 2017-03-15
PL2794603T3 (pl) 2017-08-31
AU2012357106A1 (en) 2014-06-05

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