HK1200439A1 - Derivatives of 1-(2-halo-biphenyl-4-yl)-alkanecarboxylic acids for the treatment of neurodegenerative diseases 1-(2---4-)- - Google Patents
Derivatives of 1-(2-halo-biphenyl-4-yl)-alkanecarboxylic acids for the treatment of neurodegenerative diseases 1-(2---4-)-Info
- Publication number
- HK1200439A1 HK1200439A1 HK15100809.4A HK15100809A HK1200439A1 HK 1200439 A1 HK1200439 A1 HK 1200439A1 HK 15100809 A HK15100809 A HK 15100809A HK 1200439 A1 HK1200439 A1 HK 1200439A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- biphenyl
- halo
- derivatives
- treatment
- neurodegenerative diseases
- Prior art date
Links
- 230000004770 neurodegeneration Effects 0.000 title 1
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/62—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/36—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/16—Unsaturated compounds
- C07C61/40—Unsaturated compounds containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C69/753—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of polycyclic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12163074 | 2012-04-04 | ||
PCT/EP2013/057025 WO2013150072A1 (en) | 2012-04-04 | 2013-04-03 | Derivatives of 1-(2-halo-biphenyl-4-yl)- alkanecarboxylic acids for the treatment of neurodegenerative diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1200439A1 true HK1200439A1 (en) | 2015-08-07 |
Family
ID=48227176
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15100809.4A HK1200439A1 (en) | 2012-04-04 | 2015-01-23 | Derivatives of 1-(2-halo-biphenyl-4-yl)-alkanecarboxylic acids for the treatment of neurodegenerative diseases 1-(2---4-)- |
Country Status (10)
Country | Link |
---|---|
US (1) | US8835494B2 (xx) |
EP (1) | EP2834214A1 (xx) |
KR (1) | KR20140144178A (xx) |
CN (1) | CN104169251A (xx) |
AR (1) | AR090581A1 (xx) |
BR (1) | BR112014023670A8 (xx) |
CA (1) | CA2869418A1 (xx) |
HK (1) | HK1200439A1 (xx) |
RU (1) | RU2014139971A (xx) |
WO (1) | WO2013150072A1 (xx) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015181094A1 (en) * | 2014-05-26 | 2015-12-03 | Chiesi Farmaceutici S.P.A. | 1-(2-fluorobiphenyl-4-yl)-cyclopropanecarboxylic acid derivatives for the treatment of down's syndrome |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE409176T1 (de) | 2003-02-21 | 2008-10-15 | Chiesi Farma Spa | 1-phenylalkancarbonsäurederivate zur behandlung neurodegenerativer erkrankungen |
US7135575B2 (en) * | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
PT1778623E (pt) | 2004-08-03 | 2008-09-29 | Chiesi Farma Spa | Derivados dos ácidos 1-fenilalcanocarboxílicos para o tratamento de doenças neurodegenerativas |
EP2133322A1 (en) | 2008-06-11 | 2009-12-16 | CHIESI FARMACEUTICI S.p.A. | Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid |
CN102596879B (zh) | 2009-08-04 | 2015-01-28 | 奇斯药制品公司 | 制备1-(2-卤代联苯-4-基)-环丙烷羧酸的衍生物的方法 |
-
2013
- 2013-04-03 US US13/855,915 patent/US8835494B2/en not_active Expired - Fee Related
- 2013-04-03 CA CA2869418A patent/CA2869418A1/en not_active Abandoned
- 2013-04-03 EP EP13719425.4A patent/EP2834214A1/en not_active Withdrawn
- 2013-04-03 WO PCT/EP2013/057025 patent/WO2013150072A1/en active Application Filing
- 2013-04-03 RU RU2014139971A patent/RU2014139971A/ru not_active Application Discontinuation
- 2013-04-03 CN CN201380014900.5A patent/CN104169251A/zh active Pending
- 2013-04-03 KR KR1020147023643A patent/KR20140144178A/ko not_active Application Discontinuation
- 2013-04-03 AR ARP130101076A patent/AR090581A1/es unknown
- 2013-04-03 BR BR112014023670A patent/BR112014023670A8/pt not_active IP Right Cessation
-
2015
- 2015-01-23 HK HK15100809.4A patent/HK1200439A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO2013150072A1 (en) | 2013-10-10 |
US8835494B2 (en) | 2014-09-16 |
RU2014139971A (ru) | 2016-04-20 |
CA2869418A1 (en) | 2013-10-10 |
AR090581A1 (es) | 2014-11-19 |
KR20140144178A (ko) | 2014-12-18 |
BR112014023670A2 (xx) | 2017-06-20 |
CN104169251A (zh) | 2014-11-26 |
US20130267592A1 (en) | 2013-10-10 |
BR112014023670A8 (pt) | 2017-07-25 |
EP2834214A1 (en) | 2015-02-11 |
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