HK1197552A1 - 阿爾法-及伽瑪- 類似物 - Google Patents
阿爾法-及伽瑪- 類似物Info
- Publication number
- HK1197552A1 HK1197552A1 HK14110565.8A HK14110565A HK1197552A1 HK 1197552 A1 HK1197552 A1 HK 1197552A1 HK 14110565 A HK14110565 A HK 14110565A HK 1197552 A1 HK1197552 A1 HK 1197552A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- msh
- gamma
- alpha
- analogues
- msh analogues
- Prior art date
Links
- GZWUQPQBOGLSIM-VOOUCTBASA-N γ msh Chemical class C([C@H](N)C(=O)N[C@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)NCC(O)=O)C(C)C)C1=CC=C(O)C=C1 GZWUQPQBOGLSIM-VOOUCTBASA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
- C07K14/685—Alpha-melanotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261716032P | 2012-10-19 | 2012-10-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1197552A1 true HK1197552A1 (zh) | 2015-01-23 |
Family
ID=49448156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK14110565.8A HK1197552A1 (zh) | 2012-10-19 | 2014-10-22 | 阿爾法-及伽瑪- 類似物 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US9217023B2 (zh) |
| EP (2) | EP2944650A1 (zh) |
| JP (1) | JP6429782B2 (zh) |
| CN (1) | CN104822702B (zh) |
| AU (1) | AU2013333765B2 (zh) |
| CA (1) | CA2888277C (zh) |
| DK (1) | DK2722340T3 (zh) |
| ES (1) | ES2538702T3 (zh) |
| HK (1) | HK1197552A1 (zh) |
| HU (1) | HUE025870T2 (zh) |
| PL (1) | PL2722340T3 (zh) |
| RU (1) | RU2668791C2 (zh) |
| WO (1) | WO2014060606A1 (zh) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2668791C2 (ru) | 2012-10-19 | 2018-10-02 | ТиЭксПи ФАРМА ГМБХ | АНАЛОГИ АЛЬФА- и ГАММА-MSH |
| WO2015162483A1 (en) * | 2014-04-22 | 2015-10-29 | Txp Pharma Gmbh | Alpha- and gamma-msh analogues |
| AU2015249540B2 (en) * | 2014-04-22 | 2019-08-22 | Txp Pharma Gmbh | Peptide analogues with branched amino acid probe(s) |
| WO2016066700A1 (en) * | 2014-10-28 | 2016-05-06 | Clinuvel Ag | New indication for alpha-msh analogues |
| WO2016066702A1 (en) * | 2014-10-28 | 2016-05-06 | Clinuvel Ag | Inflammatory disease |
| WO2017068020A1 (en) | 2015-10-20 | 2017-04-27 | Txp Pharma Gmbh | W-peptide analog |
| BR112023002608A2 (pt) | 2020-08-12 | 2023-05-09 | Txp Pharma Ag | Análogo de peptídeo de exendina-4, e, método para tratamento de diabetes mellitus tipo 2, obesidade e/ou intensificação da saciedade |
| WO2022251650A1 (en) * | 2021-05-27 | 2022-12-01 | The Regents Of The University Of Michigan | Mc3r agonist peptides |
| WO2024030977A2 (en) * | 2022-08-03 | 2024-02-08 | Sightstream Biotherapeutics, Inc. | Novel melanocortin analogs |
| CN117106057A (zh) * | 2022-08-19 | 2023-11-24 | 南京汉欣医药科技有限公司 | 一种高纯的人促肾上腺皮质激素或其类似物及其规模化制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4356108A (en) | 1979-12-20 | 1982-10-26 | The Mead Corporation | Encapsulation process |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US5597894A (en) | 1995-06-05 | 1997-01-28 | The Louisiana State University Medical Center Foundation | Multi-tyrosinated somatostatin analogs |
| AU5348098A (en) | 1996-12-17 | 1998-07-15 | Quadrant Holdings Cambridge Limited | Melanocortins |
| CA2321026A1 (en) | 1998-03-09 | 1999-09-16 | Zealand Pharmaceuticals A/S | Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis |
| SE9801571D0 (sv) | 1998-05-05 | 1998-05-05 | Wapharm Ab | Melanokortin-1-receptorselektiva föreningar |
| AU7593001A (en) | 2000-07-14 | 2002-01-30 | Zycos Inc | Alpha-msh related compounds and methods of use |
| US8912144B2 (en) | 2003-12-16 | 2014-12-16 | Children's Medical Center Corporation | Method for treating stroke via administration of NEP1-40 and inosine |
| ES2877349T3 (es) * | 2005-07-08 | 2021-11-16 | Ipsen Pharma | Ligandos de los receptores de la melanocortina |
| NZ566489A (en) * | 2005-08-26 | 2008-10-31 | Action Pharma As | Therapeutically active alpha-MSH analogues |
| RU2668791C2 (ru) | 2012-10-19 | 2018-10-02 | ТиЭксПи ФАРМА ГМБХ | АНАЛОГИ АЛЬФА- и ГАММА-MSH |
| AU2015249540B2 (en) | 2014-04-22 | 2019-08-22 | Txp Pharma Gmbh | Peptide analogues with branched amino acid probe(s) |
| WO2015162483A1 (en) | 2014-04-22 | 2015-10-29 | Txp Pharma Gmbh | Alpha- and gamma-msh analogues |
| WO2015162486A1 (en) | 2014-04-22 | 2015-10-29 | Txp Pharma Gmbh | Linear gamma msh with c- and / or n-terminal extensions of lysine and / or glutamic acid residues |
-
2013
- 2013-10-21 RU RU2015118576A patent/RU2668791C2/ru active
- 2013-10-21 HU HUE13189492A patent/HUE025870T2/en unknown
- 2013-10-21 EP EP15157262.5A patent/EP2944650A1/en not_active Withdrawn
- 2013-10-21 US US14/058,790 patent/US9217023B2/en active Active
- 2013-10-21 JP JP2015537289A patent/JP6429782B2/ja active Active
- 2013-10-21 ES ES13189492.5T patent/ES2538702T3/es active Active
- 2013-10-21 DK DK13189492.5T patent/DK2722340T3/en active
- 2013-10-21 AU AU2013333765A patent/AU2013333765B2/en active Active
- 2013-10-21 EP EP13189492.5A patent/EP2722340B1/en active Active
- 2013-10-21 PL PL13189492T patent/PL2722340T3/pl unknown
- 2013-10-21 WO PCT/EP2013/071935 patent/WO2014060606A1/en active Application Filing
- 2013-10-21 CN CN201380062117.6A patent/CN104822702B/zh active Active
- 2013-10-21 CA CA2888277A patent/CA2888277C/en active Active
-
2014
- 2014-10-22 HK HK14110565.8A patent/HK1197552A1/zh unknown
-
2015
- 2015-11-24 US US14/951,305 patent/US9486495B2/en active Active
-
2016
- 2016-10-10 US US15/289,562 patent/US9951116B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2888277A1 (en) | 2014-04-24 |
| DK2722340T3 (en) | 2015-06-08 |
| US9486495B2 (en) | 2016-11-08 |
| WO2014060606A1 (en) | 2014-04-24 |
| CN104822702B (zh) | 2019-07-30 |
| US9217023B2 (en) | 2015-12-22 |
| US20170174738A1 (en) | 2017-06-22 |
| JP6429782B2 (ja) | 2018-11-28 |
| EP2722340B1 (en) | 2015-03-04 |
| AU2013333765B2 (en) | 2017-12-07 |
| CA2888277C (en) | 2023-09-05 |
| BR112015008767A2 (pt) | 2017-07-04 |
| JP2015534972A (ja) | 2015-12-07 |
| EP2944650A1 (en) | 2015-11-18 |
| PL2722340T3 (pl) | 2015-08-31 |
| ES2538702T3 (es) | 2015-06-23 |
| CN104822702A (zh) | 2015-08-05 |
| US20140155328A1 (en) | 2014-06-05 |
| HUE025870T2 (en) | 2016-05-30 |
| RU2015118576A (ru) | 2016-12-10 |
| AU2013333765A1 (en) | 2015-05-28 |
| RU2668791C2 (ru) | 2018-10-02 |
| US9951116B2 (en) | 2018-04-24 |
| EP2722340A1 (en) | 2014-04-23 |
| US20160074469A1 (en) | 2016-03-17 |
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