HK1189487A1 - 大黃酸在製備治療胰腺纖維化藥物中的應用 - Google Patents

大黃酸在製備治療胰腺纖維化藥物中的應用

Info

Publication number
HK1189487A1
HK1189487A1 HK14102293.4A HK14102293A HK1189487A1 HK 1189487 A1 HK1189487 A1 HK 1189487A1 HK 14102293 A HK14102293 A HK 14102293A HK 1189487 A1 HK1189487 A1 HK 1189487A1
Authority
HK
Hong Kong
Prior art keywords
rhein
medicament
manufacturing
treating pancreatic
pancreatic fibrosis
Prior art date
Application number
HK14102293.4A
Other languages
English (en)
Inventor
卞兆祥
曾少慧
吕愛平
肖海濤
秦紅岩
陳新滋
徐宏喜
陳士林
楊大堅
Original Assignee
香港浸會大學
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 香港浸會大學 filed Critical 香港浸會大學
Publication of HK1189487A1 publication Critical patent/HK1189487A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK14102293.4A 2012-06-04 2014-03-06 大黃酸在製備治療胰腺纖維化藥物中的應用 HK1189487A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261655472P 2012-06-04 2012-06-04
US13/831,990 US8652540B2 (en) 2012-06-04 2013-03-15 Method of using rhein for treating fibrotic conditions and tumors

Publications (1)

Publication Number Publication Date
HK1189487A1 true HK1189487A1 (zh) 2014-06-13

Family

ID=49670551

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14102293.4A HK1189487A1 (zh) 2012-06-04 2014-03-06 大黃酸在製備治療胰腺纖維化藥物中的應用

Country Status (3)

Country Link
US (1) US8652540B2 (zh)
CN (1) CN103505448B (zh)
HK (1) HK1189487A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104257768A (zh) * 2014-09-28 2015-01-07 江西百神药业股份有限公司 各种成分比例稳定均一的大黄总蒽醌及其组合物用于治疗胰腺炎
CN104825812A (zh) * 2015-05-02 2015-08-12 淄博齐鼎立专利信息咨询有限公司 中药组合物在制备预防或治疗胰腺纤维化药物中的应用
CN107693529B (zh) * 2015-06-23 2020-04-24 香港浸会大学 抑制在有需要的主体内食道肿瘤生长的方法及黄酮醇化合物作为制备治疗食道肿瘤药物应用
MX2018002049A (es) * 2015-08-17 2018-06-15 Twi Biotechnology Inc Diacereina o sus analogos para inhibir la expresion de proteina como mota relacionada a la apoptosis que contiene un dominio de reclutamiento de caspasa (asc), expresion de dominios de pirina y familia nlr que contienen 3 (nlrp3) y/o formacion de complejo de inflamasoma de nlrp3.
CN107243079B (zh) * 2017-04-19 2020-08-25 温州医科大学 一种含大黄酸的药物组合物及其在制备抗肿瘤药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2842738B1 (fr) 2002-07-23 2006-02-10 Negma Lerads Utilisation d'une rheine pour la preparation d'un medicament pour le traitement de l'inflammation chronique, la prevention et le traitement du rejet des transplantations d'organes et de tissus
CN1306932C (zh) * 2005-06-02 2007-03-28 韩德五 一种降低人体血液中内毒素水平的药物
KR101068266B1 (ko) * 2008-10-13 2011-09-28 한국원자력연구원 방사선을 이용한 센노사이드 ａ로부터 항암효과 증진된 레인 유도체의 제조방법

Also Published As

Publication number Publication date
US8652540B2 (en) 2014-02-18
CN103505448B (zh) 2016-03-02
CN103505448A (zh) 2014-01-15
US20130323329A1 (en) 2013-12-05

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