HK1176646A1 - Methods for the detection of biologically relevant molecules and their interaction characteristics - Google Patents

Methods for the detection of biologically relevant molecules and their interaction characteristics

Info

Publication number
HK1176646A1
HK1176646A1 HK13104223.6A HK13104223A HK1176646A1 HK 1176646 A1 HK1176646 A1 HK 1176646A1 HK 13104223 A HK13104223 A HK 13104223A HK 1176646 A1 HK1176646 A1 HK 1176646A1
Authority
HK
Hong Kong
Prior art keywords
detection
methods
biologically relevant
interaction characteristics
relevant molecules
Prior art date
Application number
HK13104223.6A
Other languages
English (en)
Chinese (zh)
Inventor
克里斯托弗.戈登.阿特伍德
Original Assignee
克里斯托弗.戈登.阿特伍德
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 克里斯托弗.戈登.阿特伍德 filed Critical 克里斯托弗.戈登.阿特伍德
Publication of HK1176646A1 publication Critical patent/HK1176646A1/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/521Single-layer analytical elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/5436Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
HK13104223.6A 2010-02-23 2013-04-08 Methods for the detection of biologically relevant molecules and their interaction characteristics HK1176646A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33867610P 2010-02-23 2010-02-23

Publications (1)

Publication Number Publication Date
HK1176646A1 true HK1176646A1 (en) 2013-08-02

Family

ID=44507153

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13104223.6A HK1176646A1 (en) 2010-02-23 2013-04-08 Methods for the detection of biologically relevant molecules and their interaction characteristics

Country Status (9)

Country Link
US (2) US8709224B2 (xx)
EP (1) EP2539462B1 (xx)
JP (1) JP5729651B2 (xx)
KR (1) KR101802541B1 (xx)
CN (1) CN102762746B (xx)
AU (1) AU2011218847B2 (xx)
CA (1) CA2788813C (xx)
HK (1) HK1176646A1 (xx)
WO (1) WO2011106198A1 (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8399006B2 (en) 2009-01-29 2013-03-19 Forsight Vision4, Inc. Posterior segment drug delivery
CA2788813C (en) 2010-02-23 2021-02-23 Christopher Gordon Atwood Methods for the detection of biologically relevant molecules and their interaction characteristics
EP2816348A1 (en) * 2013-06-20 2014-12-24 Universität Wien Electrochemical measurement device
CN103323374B (zh) * 2013-06-25 2015-10-28 中国科学院微生物研究所 一种高通量筛选生物表面活性剂的方法
JP6153856B2 (ja) * 2013-12-05 2017-06-28 株式会社日立ハイテクノロジーズ 生体分子特性解析チップ及びその製造方法
EP3377009B1 (en) 2015-11-20 2020-10-28 ForSight Vision4, Inc. Porous structures for extended release drug delivery devices
CN107024622A (zh) * 2017-05-02 2017-08-08 江苏大学 一种单雾滴荷质比测量装置及方法
WO2019106961A1 (ja) * 2017-11-28 2019-06-06 浜松ホトニクス株式会社 レーザ脱離イオン化法、質量分析方法、試料支持体、及び試料支持体の製造方法
CN111406211A (zh) * 2017-11-28 2020-07-10 浜松光子学株式会社 激光解吸电离法和质谱法
WO2019155741A1 (ja) 2018-02-09 2019-08-15 浜松ホトニクス株式会社 試料支持体
CN108469399A (zh) * 2018-05-09 2018-08-31 南京煦源生物科技有限公司 固相表面与溶液的运动方式及运动装置
CN109239406B (zh) * 2018-10-08 2020-03-31 西安交通大学 一种用于细胞器药物定位投递检测装置及投药检测方法
US11474109B2 (en) 2018-11-16 2022-10-18 Scintimetrics, Inc. Compositions and methods for controllably merging emulsion droplets and sample analysis
CN110702563B (zh) * 2019-09-18 2020-08-18 西北工业大学 一种无标记化学生物反应检测方法
WO2021097301A1 (en) * 2019-11-15 2021-05-20 Christopher Gordon Atwood Compositions and methods based on diffusion of fluorophores
CN114002296B (zh) * 2022-01-04 2022-03-29 苏州大学 生物活性物质瞬态光电压测量组件、装置及方法
CN115060772A (zh) * 2022-08-16 2022-09-16 天津市协和医药科技集团有限公司 一种基于功能化核孔膜的ca50抗原电化学检测方法

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5212065A (en) 1990-10-25 1993-05-18 International Diagnostic Systems, Corp. Rapid assay device
IL108497A0 (en) * 1993-02-01 1994-05-30 Seq Ltd Methods and apparatus for dna sequencing
US6541213B1 (en) 1996-03-29 2003-04-01 University Of Washington Microscale diffusion immunoassay
US20030211507A1 (en) 1996-03-29 2003-11-13 Anson Hatch Microscale diffusion immunoassay in hydrogels
DE19822123C2 (de) 1997-11-21 2003-02-06 Meinhard Knoll Verfahren und Vorrichtung zum Nachweis von Analyten
US7297312B2 (en) 1998-03-16 2007-11-20 University Of Cincinnati Simultaneous multianalyte electrochemical assay based on spatial resolution
ATE444481T1 (de) 1998-11-16 2009-10-15 California Inst Of Techn Gleichzeitige bestimmung von gleichgewichts- und kinetischen eigenschaften
US7306672B2 (en) 2001-04-06 2007-12-11 California Institute Of Technology Microfluidic free interface diffusion techniques
CN1238721C (zh) * 1999-12-20 2006-01-25 宾夕法尼亚州研究基金会 一种样品分析方法
DE10006309A1 (de) 2000-02-12 2001-08-23 Aventis Pharma Gmbh Verfahren zur Identifizierung von Substanzen, die die Aktivität von hyperpolarisationsaktivierten Kationen-kanälen modulieren
JP2003528309A (ja) * 2000-03-20 2003-09-24 アナリティカル バイオロジカル サービシーズ インク 蛍光を用いた検体の検出方法
WO2001070851A1 (en) 2000-03-24 2001-09-27 Pohang University Of Science And Technology A method for forming molecular layers having high density of primary amine group on solid supports
AU2001288270A1 (en) * 2000-08-16 2002-02-25 Vanderbilt University System and method of infrared matrix-assisted laser desorption/ionization mass spectrometry in polyacrylamide gels
US7069445B2 (en) 2001-11-30 2006-06-27 Lenovo (Singapore) Pte. Ltd System and method for migration of a version of a bootable program
US7081213B2 (en) 2002-05-14 2006-07-25 Clariant Finance (Bvi) Limited Stabilizer mixtures for the protection of polymer substrates
US20050019784A1 (en) * 2002-05-20 2005-01-27 Xing Su Method and apparatus for nucleic acid sequencing and identification
CA2387316A1 (en) 2002-05-31 2003-11-30 The University Of Western Ontario Method and apparatus for the detection of noncovalent interactions by mass spectrometry - based diffusion measurements
US7732127B2 (en) 2002-12-20 2010-06-08 Acea Biosciences, Inc. Dynamic monitoring of cell adhesion and spreading using the RT-CES system
WO2005047482A2 (en) 2003-11-12 2005-05-26 Xiao Xu Real time electronic cell sensing systems and applications for cell-based assays
US20050136419A1 (en) 2003-03-28 2005-06-23 The Regents Of The University Of California Method and apparatus for nanogap device and array
US20050095599A1 (en) * 2003-10-30 2005-05-05 Pittaro Richard J. Detection and identification of biopolymers using fluorescence quenching
US20050109621A1 (en) 2003-11-26 2005-05-26 Peter C. Hauser Method and apparatus for performing high-voltage contactless conductivity (HV-CCD) electrophoresis
EP1548444A1 (en) * 2003-12-23 2005-06-29 Paul Scherrer Institut An assay chip, and uses of said assay chip to determine molecular structures and functions
US8673621B2 (en) 2005-08-12 2014-03-18 Postech Foundation Biomolecule interaction using atomic force microscope
WO2006036592A1 (en) 2004-09-23 2006-04-06 University Of Washington Microscale diffusion immunoassay utilizing multivalent reactants
US20060073489A1 (en) * 2004-10-05 2006-04-06 Gangqiang Li Nanopore separation devices and methods of using same
WO2007084103A2 (en) * 2004-12-21 2007-07-26 The Texas A & M University System High temperature ion channels and pores
CA2596121A1 (en) * 2005-01-31 2006-08-10 The Board Of Trustees Of The University Of Illinois Methods and devices for characterizing particles in clear and turbid media
US20100261615A9 (en) 2005-08-12 2010-10-14 Joon Won Park Atomic force microscope as an analyzing tool for biochip
WO2007067759A2 (en) * 2005-12-08 2007-06-14 Protein Discovery, Inc. Methods and devices for concentration and fractionation of analytes for chemical analysis
EP1963819A2 (en) * 2005-12-22 2008-09-03 Honeywell International, Inc. Portable sample analyzer system
CA2635670C (en) 2005-12-27 2011-07-12 Bayer Healthcare Llc Electrochemical sensor system using a substrate with at least one aperture and method of making the same
US20070298511A1 (en) * 2006-04-27 2007-12-27 The Texas A&M University System Nanopore sensor system
US20100025263A1 (en) * 2006-05-05 2010-02-04 University Of Utah Research Foundation Nanopore particle analyzer, method of preparation and use thereof
EP1930716A1 (de) 2006-12-08 2008-06-11 Micronas GmbH Verfahren und Vorrichtung zur Detektion eines Liganden in einem Fluid
JP5030166B2 (ja) * 2007-05-01 2012-09-19 独立行政法人産業技術総合研究所 レーザー脱離イオン化質量分析に使用される試料支持用基板の試験方法
US9121843B2 (en) * 2007-05-08 2015-09-01 Trustees Of Boston University Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
WO2009012340A2 (en) 2007-07-16 2009-01-22 California Institute Of Technology Microfluidic devices, methods and systems for detecting target molecules
GB0717150D0 (en) * 2007-09-04 2007-10-17 Univ Warwick Apparatus and method
CA2788813C (en) 2010-02-23 2021-02-23 Christopher Gordon Atwood Methods for the detection of biologically relevant molecules and their interaction characteristics

Also Published As

Publication number Publication date
EP2539462B1 (en) 2017-10-18
EP2539462A4 (en) 2013-07-10
JP2013520655A (ja) 2013-06-06
US8709224B2 (en) 2014-04-29
CA2788813C (en) 2021-02-23
AU2011218847B2 (en) 2015-03-12
CN102762746B (zh) 2015-04-29
AU2011218847A1 (en) 2012-08-23
EP2539462A1 (en) 2013-01-02
US20120181176A1 (en) 2012-07-19
CN102762746A (zh) 2012-10-31
CA2788813A1 (en) 2011-09-01
JP5729651B2 (ja) 2015-06-03
US20140186822A1 (en) 2014-07-03
KR101802541B1 (ko) 2017-11-30
KR20130045232A (ko) 2013-05-03
US9423378B2 (en) 2016-08-23
WO2011106198A1 (en) 2011-09-01

Similar Documents

Publication Publication Date Title
HK1176646A1 (en) Methods for the detection of biologically relevant molecules and their interaction characteristics
IL252398A0 (en) cd37-binding molecules and their immunoconjugates
GB201013989D0 (en) Biological materials and methods of using the same
EP2632490A4 (en) NOVEL MOLECULES BINDING TO THE EGF RECEPTOR AND IMMUNOCONJUGATES THEREOF
GB201010557D0 (en) RNA molecules and uses thereof
ZA201302022B (en) Nmr systems and methods for the detection of analytes
EP2613138A4 (en) PROCESS FOR DETECTION OF BIOLOGICAL SUBSTANCES
EP2611832A4 (en) ANTI-CXCL13 ANTIBODIES AND METHOD FOR THEIR USE
ZA201300612B (en) Novel bacteria and methods of use thereof
HK1182117A1 (zh) 抗生腱蛋白- 抗體及使用方法
LT2946791T (lt) Anti-cd277 antikūnai ir jų panaudojimas
EP2596343A4 (en) BIOSENSOR DEVICES AND METHOD THEREFOR
IL259481A (en) System and methods for automated synthesis of small molecules
PL3650125T3 (pl) Rozpylacz cieczy i sposoby
EP2558496A4 (en) ANTIBODIES TO POLYUBIQUITINE AND METHOD FOR THEIR USE
EP2632952A4 (en) ANTI-SOD1 ANTIBODIES AND USES THEREOF
ZA201300174B (en) Anti-neuropilin antibodies and methods of use
GB201110550D0 (en) Matric potential sensor and related methods
EP2753359A4 (en) SERPINF2 BINDEMOLEKÜLE AND METHOD FOR THEIR USE
GB201020357D0 (en) Compounds and methods of making the same
EP2545378A4 (en) ANTI-LG3 ANTIBODIES AND USES THEREOF
GB201015790D0 (en) Thrombin-binding antibody molecules and uses thereof
GB201003886D0 (en) Biosensor apparatus and use thereof
GB201022111D0 (en) Method of determining number or concentration of molecules
GB201019361D0 (en) Biosensor and uses thereof