HK1175993A1 - 在胰島移植中作為佐劑的 抑制劑 - Google Patents

在胰島移植中作為佐劑的 抑制劑

Info

Publication number
HK1175993A1
HK1175993A1 HK13103030.1A HK13103030A HK1175993A1 HK 1175993 A1 HK1175993 A1 HK 1175993A1 HK 13103030 A HK13103030 A HK 13103030A HK 1175993 A1 HK1175993 A1 HK 1175993A1
Authority
HK
Hong Kong
Prior art keywords
cxcr1
transplant
adjuvants
inhibitors
pancreatic islets
Prior art date
Application number
HK13103030.1A
Other languages
English (en)
Inventor
洛倫佐．皮耶蒙蒂
路易莎．達豐希奧
馬爾塞洛．阿萊格雷蒂
Original Assignee
多姆皮制藥公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 多姆皮制藥公司 filed Critical 多姆皮制藥公司
Publication of HK1175993A1 publication Critical patent/HK1175993A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51—Y being a hydrogen or a carbon atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK13103030.1A 2009-10-06 2013-03-12 在胰島移植中作為佐劑的 抑制劑 HK1175993A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09172364A EP2308484A1 (en) 2009-10-06 2009-10-06 Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets
PCT/EP2010/064921 WO2011042466A1 (en) 2009-10-06 2010-10-06 Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets

Publications (1)

Publication Number Publication Date
HK1175993A1 true HK1175993A1 (zh) 2013-07-19

Family

ID=41818891

Family Applications (2)

Application Number Title Priority Date Filing Date
HK13103030.1A HK1175993A1 (zh) 2009-10-06 2013-03-12 在胰島移植中作為佐劑的 抑制劑
HK16101720.7A HK1213777A1 (zh) 2009-10-06 2016-02-18 在胰島移植中作為佐劑的 抑制劑

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK16101720.7A HK1213777A1 (zh) 2009-10-06 2016-02-18 在胰島移植中作為佐劑的 抑制劑

Country Status (24)

Country Link
US (1) US20120202884A1 (zh)
EP (2) EP2308484A1 (zh)
JP (2) JP5834010B2 (zh)
KR (2) KR101759362B1 (zh)
CN (2) CN104906572A (zh)
AU (1) AU2010305385B2 (zh)
BR (1) BR112012007991B8 (zh)
CA (1) CA2775902C (zh)
CY (1) CY1115018T1 (zh)
DK (1) DK2485723T3 (zh)
EA (1) EA021298B1 (zh)
ES (1) ES2451349T3 (zh)
HK (2) HK1175993A1 (zh)
HR (1) HRP20140202T1 (zh)
IL (1) IL219037A (zh)
ME (1) ME01719B (zh)
MX (1) MX2012004082A (zh)
NZ (1) NZ599172A (zh)
PL (1) PL2485723T3 (zh)
PT (1) PT2485723E (zh)
RS (1) RS53249B (zh)
SI (1) SI2485723T1 (zh)
SM (1) SMT201400033B (zh)
WO (1) WO2011042466A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2308484A1 (en) * 2009-10-06 2011-04-13 Dompé S.p.a. Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets
EP2308485A1 (en) * 2009-10-06 2011-04-13 Dompé S.p.a. Sulfonamides for the prevention of diabetes
CN103159652B (zh) * 2011-12-19 2016-06-08 天津市国际生物医药联合研究院 亚磺酰胺类化合物的制备及其应用
EP3441474B1 (en) 2013-06-18 2020-07-22 New York University Pharmaceutical compositions containing a mutated leukocidin e
SG11201804625TA (en) 2015-12-29 2018-06-28 Uop Llc Binderless zeolitic adsorbents and methods for producing binderless zeolitic adsorbents
AU2017339942B2 (en) 2016-10-03 2023-06-29 Dompe Farmaceutici S.P.A. Prevention and treatment of diabetic nephropathy

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303249B1 (it) 1998-10-23 2000-11-06 Dompe Spa Alcune n-(2-aril-propionil)-solfonammidi e preparazionifarmaceutiche che le contengono.
US20020042370A1 (en) * 2000-04-14 2002-04-11 Millennium Pharmaceuticals, Inc. Method of treating graft rejection using inhibitors of CCR2 function
US20020018776A1 (en) * 2000-04-14 2002-02-14 Millennium Pharmaceuticals, Inc. Method of treating graft rejection using inhibitors of CXCR3 function
ITMI20010206A1 (it) * 2001-02-02 2002-08-02 Dompe Spa Uso della metansolfonammide di (r)-ibuprofene e dei suoi sali non tossici per la preparazione di medicamenti per il trattamento e la prevenz
ME01763B (me) * 2004-03-23 2010-10-31 Dompe Farm Spa Derivati 2-fenilpropionske kiseline i farmaceutske smeše koje ih sadrže
DE602004003673T2 (de) 2004-03-25 2007-10-04 Dompe' Pha.R.Ma S.P.A. Verwendung von N-(2-Aryl-propionyl)-sulfonamiden zur Behandlung von Rückenmarkverletzungen
US20050261762A1 (en) * 2004-05-21 2005-11-24 Medtronic Vascular, Inc. Medical devices to prevent or inhibit restenosis
TWI400232B (zh) * 2004-09-13 2013-07-01 Ono Pharmaceutical Co 含氮雜環衍生物及以該含氮雜環衍生物為有效成分之藥劑
JP5232144B2 (ja) * 2006-06-28 2013-07-10 サノフイ Ｃｘｃｒ２阻害剤
EP2066335A4 (en) * 2006-09-26 2010-01-20 Univ Case Western Reserve CYTOKINE SIGNALING
JP2011526244A (ja) 2008-03-20 2011-10-06 カロラス セラピューティクス， インク． 炎症の処置方法
EP2308484A1 (en) * 2009-10-06 2011-04-13 Dompé S.p.a. Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets

Also Published As

Publication number Publication date
ES2451349T3 (es) 2014-03-26
RS53249B (en) 2014-08-29
EP2485723B1 (en) 2013-12-11
PL2485723T3 (pl) 2014-07-31
EA201270513A1 (ru) 2012-11-30
CN102665703B (zh) 2016-04-20
CA2775902C (en) 2016-11-29
EP2485723A1 (en) 2012-08-15
HRP20140202T1 (en) 2014-05-23
WO2011042466A1 (en) 2011-04-14
SI2485723T1 (sl) 2014-06-30
JP2013506704A (ja) 2013-02-28
KR101759362B1 (ko) 2017-07-18
IL219037A (en) 2015-01-29
NZ599172A (en) 2014-03-28
DK2485723T3 (en) 2014-03-17
EP2308484A1 (en) 2011-04-13
BR112012007991B1 (pt) 2020-12-15
SMT201400033B (it) 2014-07-07
KR101817912B1 (ko) 2018-02-21
AU2010305385A1 (en) 2012-04-26
IL219037A0 (en) 2012-06-28
AU2010305385B2 (en) 2016-04-21
JP5834010B2 (ja) 2015-12-16
CA2775902A1 (en) 2011-04-14
PT2485723E (pt) 2014-03-13
JP6097328B2 (ja) 2017-03-15
CN102665703A (zh) 2012-09-12
CY1115018T1 (el) 2017-01-25
CN104906572A (zh) 2015-09-16
KR20170068625A (ko) 2017-06-19
KR20120083440A (ko) 2012-07-25
JP2015145404A (ja) 2015-08-13
EA021298B1 (ru) 2015-05-29
BR112012007991A2 (pt) 2017-07-25
HK1213777A1 (zh) 2016-07-15
ME01719B (me) 2014-09-20
US20120202884A1 (en) 2012-08-09
BR112012007991B8 (pt) 2021-05-25
MX2012004082A (es) 2012-07-25

Similar Documents

Publication Publication Date Title
IL263729A (en) Preparations and methods for removing biofilms
HK1213777A1 (zh) 在胰島移植中作為佐劑的 抑制劑
EP2486061A4 (en) COMPOSITIONS AND METHODS FOR THE TRANSPORT OF THERAPEUTICS
EP2456856A4 (en) METHOD AND COMPOSITIONS FOR IMPROVING THE VITABILITY OF CRYOCONESERVED CELLS
EP2485731A4 (en) Heterocyclic compounds as PDK1 inhibitors
DK2504353T4 (da) Lipopeptidsammensætninger og tilsvarende fremgangsmåder
HK1165425A1 (zh) 作為 抑制劑的 -環烷基氨基喹諾酮
HRP20141057T1 (en) Novel compound useful for the treatment of degenerative and inflammatory diseases
EP2482761A4 (en) TISSUE TRANSPLANT COMPOSITIONS AND METHOD FOR THEIR USE
IL218018A0 (en) Novel n-substituted-pyrrolidines as inhibitors of mdm2-p-53 interactions
SMT201400114B (it) Derivati di 2-arilimidazolo come inibitori dell'enzima pde10a
EP2575444A4 (en) DILUTABLE BIOZIDE COMPOSITIONS AND USE METHOD THEREFOR
HK1156306A1 (zh) 作為 -脯氨酰基- -羥化酶抑制劑的取代的二氫吡唑啉酮類化合物
IL215150A (en) An artificial stone panel or table created specifically for home use
EP2384120A4 (en) AUXILIARY COMPOSITIONS AND METHOD FOR THEIR USE
EP2539444A4 (en) COMPOSITIONS AND METHODS FOR THE PRODUCTION OF L-HOMOALANINE
GB0806281D0 (en) Markers of Oocyte viability
GB0700380D0 (en) Storage Of Ampoules
PL2700313T3 (pl) Kompozycje biobójcze zawierające glutaraldehyd i tris(hydroksymetylo)nitrometan i sposoby ich stosowania
EP2455089A4 (en) INHIBITOR OF RISE OF GIP IN BLOOD
EP2305025A4 (en) GEN-MANIPULATED PLANT FOR THE BIOSYNTHESIS OF CAPSINOID
EP2157848A4 (en) PLANT CRYOPROTECTIVE COMPOSITIONS AND METHODS OF USE
EP2310495A4 (en) COMPOSITIONS AND METHODS FOR GENERATING HERPES ALPHA VIRUSES
GB2499769A8 (en) Composition for inhibiting the growth of mammalianhair
GB201015883D0 (en) Replica westmoorland rockery stones

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20221006