HK1173457A1 - 蛋白晶體和交聯晶體及其使用方法 - Google Patents

蛋白晶體和交聯晶體及其使用方法

Info

Publication number
HK1173457A1
HK1173457A1 HK13100618.7A HK13100618A HK1173457A1 HK 1173457 A1 HK1173457 A1 HK 1173457A1 HK 13100618 A HK13100618 A HK 13100618A HK 1173457 A1 HK1173457 A1 HK 1173457A1
Authority
HK
Hong Kong
Prior art keywords
crystals
methods
cross
linked
protein
Prior art date
Application number
HK13100618.7A
Other languages
English (en)
Inventor
Bhami Shenoy
Reena Patel
Sibyl Baladi
Margaret Mcgrath
Nazer Khalaf
Chanchal Randhawa
Original Assignee
Ajinomoto Althea Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Althea Inc filed Critical Ajinomoto Althea Inc
Publication of HK1173457A1 publication Critical patent/HK1173457A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
HK13100618.7A 2009-09-15 2013-01-15 蛋白晶體和交聯晶體及其使用方法 HK1173457A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24253709P 2009-09-15 2009-09-15
PCT/US2010/048664 WO2011034822A1 (en) 2009-09-15 2010-09-13 Protein a crystals and cross-linked crystals and methods of use thereof

Publications (1)

Publication Number Publication Date
HK1173457A1 true HK1173457A1 (zh) 2013-05-16

Family

ID=43758972

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13100618.7A HK1173457A1 (zh) 2009-09-15 2013-01-15 蛋白晶體和交聯晶體及其使用方法

Country Status (12)

Country Link
US (2) US8921531B2 (zh)
EP (1) EP2478005B1 (zh)
JP (1) JP5700581B2 (zh)
KR (1) KR101530417B1 (zh)
CN (1) CN102753570B (zh)
BR (1) BR112012005869A2 (zh)
CA (1) CA2774212C (zh)
DK (1) DK2478005T3 (zh)
EA (1) EA033141B1 (zh)
ES (1) ES2530578T3 (zh)
HK (1) HK1173457A1 (zh)
WO (1) WO2011034822A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2478005T3 (en) 2009-09-15 2015-02-16 Ajinomoto Althea Inc Protein a crystals and cross bound crystals and methods of use thereof
JP5963538B2 (ja) * 2012-02-24 2016-08-03 三井造船株式会社 モーレラ属細菌の遺伝子組換え法
JP6147340B2 (ja) * 2013-05-29 2017-06-14 Jsr株式会社 洗浄用組成物、タンパク質精製方法、及びタンパク質
WO2015103545A1 (en) * 2014-01-03 2015-07-09 Bio-Rad Laboratories, Inc. Removal of impurities from protein a eluates
WO2016031932A1 (ja) * 2014-08-27 2016-03-03 田辺三菱製薬株式会社 アルカリ洗浄によるＦｃ領域を有するタンパク質の製造方法
AR103726A1 (es) * 2015-02-27 2017-05-31 Merck Sharp & Dohme Cristales de anticuerpos monoclonales anti-pd-1 humanos
BR112019011921A2 (pt) * 2016-12-12 2019-11-05 Hurrah S A R L polipeptídeo engenheirado que liga imunoglobulinas ou compostos contendo imunoglobulina, matriz de separação, composição, proteína, meio cromatográfico e método de purificação de uma imunoglobulina
US11845798B2 (en) 2017-05-02 2023-12-19 Merck Sharp & Dohme Llc Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies
JOP20190260A1 (ar) 2017-05-02 2019-10-31 Merck Sharp & Dohme صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
CN112816700A (zh) * 2020-12-28 2021-05-18 杭州新脉生物科技有限公司 一种检测尿液中hiv抗体的胶体金试纸条

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS508549A (zh) 1973-05-21 1975-01-29
SG70966A1 (en) * 1990-08-03 2000-03-21 Vertex Pharma Use of crosslinked crystals as a novel form of enzyme immobilization
US5618710A (en) 1990-08-03 1997-04-08 Vertex Pharmaceuticals, Inc. Crosslinked enzyme crystals
AU628264B2 (en) 1990-08-14 1992-09-10 Oracle International Corporation Methods and apparatus for providing a client interface to an object-oriented invocation of an application
US6447777B1 (en) 1996-03-29 2002-09-10 David S. Terman Polymerized staphylococcal protein a for treatment of diseases
US6140475A (en) 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
US6541606B2 (en) * 1997-12-31 2003-04-01 Altus Biologics Inc. Stabilized protein crystals formulations containing them and methods of making them
GB0304576D0 (en) 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
CN101120017A (zh) * 2004-08-30 2008-02-06 英国龙沙生物医药股份有限公司 用于纯化抗体的亲和力加离子交换层析
DK2478005T3 (en) 2009-09-15 2015-02-16 Ajinomoto Althea Inc Protein a crystals and cross bound crystals and methods of use thereof

Also Published As

Publication number Publication date
ES2530578T3 (es) 2015-03-03
EP2478005B1 (en) 2014-11-12
CA2774212C (en) 2018-01-30
KR101530417B1 (ko) 2015-06-19
BR112012005869A2 (pt) 2017-01-31
EP2478005A1 (en) 2012-07-25
US20150239962A1 (en) 2015-08-27
US9273123B2 (en) 2016-03-01
JP2013504621A (ja) 2013-02-07
CN102753570A (zh) 2012-10-24
EP2478005A4 (en) 2013-07-24
CN102753570B (zh) 2016-01-20
US20130053548A1 (en) 2013-02-28
EA033141B1 (ru) 2019-09-30
WO2011034822A1 (en) 2011-03-24
US8921531B2 (en) 2014-12-30
EA201270425A1 (ru) 2013-02-28
CA2774212A1 (en) 2011-03-24
JP5700581B2 (ja) 2015-04-15
KR20140002459A (ko) 2014-01-08
DK2478005T3 (en) 2015-02-16

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20200917