HK1169336A1 - Materials and methods relating to glycosylation of a therapeutic polypeptide - Google Patents

Materials and methods relating to glycosylation of a therapeutic polypeptide

Info

Publication number
HK1169336A1
HK1169336A1 HK12110238.7A HK12110238A HK1169336A1 HK 1169336 A1 HK1169336 A1 HK 1169336A1 HK 12110238 A HK12110238 A HK 12110238A HK 1169336 A1 HK1169336 A1 HK 1169336A1
Authority
HK
Hong Kong
Prior art keywords
glycosylation
materials
therapeutic polypeptide
methods relating
relating
Prior art date
Application number
HK12110238.7A
Other languages
English (en)
Chinese (zh)
Inventor
Andrew Graham Watts
Amanda Barbara Mackenzie
Terrence Kantner
Original Assignee
Glythera Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glythera Ltd filed Critical Glythera Ltd
Publication of HK1169336A1 publication Critical patent/HK1169336A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
HK12110238.7A 2009-06-16 2012-10-17 Materials and methods relating to glycosylation of a therapeutic polypeptide HK1169336A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18743409P 2009-06-16 2009-06-16
PCT/GB2010/001188 WO2010146362A2 (fr) 2009-06-16 2010-06-16 Matières et procédés liés à la glycosylation

Publications (1)

Publication Number Publication Date
HK1169336A1 true HK1169336A1 (en) 2013-02-22

Family

ID=43086298

Family Applications (1)

Application Number Title Priority Date Filing Date
HK12110238.7A HK1169336A1 (en) 2009-06-16 2012-10-17 Materials and methods relating to glycosylation of a therapeutic polypeptide

Country Status (9)

Country Link
US (1) US9452223B2 (fr)
EP (1) EP2442831B9 (fr)
JP (2) JP6091892B2 (fr)
CN (1) CN102481377B (fr)
CA (1) CA2768155C (fr)
ES (1) ES2560557T3 (fr)
HK (1) HK1169336A1 (fr)
PL (1) PL2442831T3 (fr)
WO (1) WO2010146362A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2768155C (fr) * 2009-06-16 2016-08-23 The University Of Bath Matieres et procedes lies a la glycosylation
TW201442721A (zh) * 2013-01-23 2014-11-16 Daiichi Sankyo Co Ltd 糖鏈修飾心房利尿鈉肽
CN106415244B (zh) * 2014-03-27 2020-04-24 中央研究院 反应性标记化合物及其用途
RU2656140C2 (ru) * 2016-11-14 2018-05-31 Федеральное государственное бюджетное учреждение "Государственный научный центр Институт иммунологии" Федерального медико-биологического агентства России Способ получения гибридного белка, состоящего из рекомбинантного белка аналога интерферона гамма, конъюгированного с олигосахаридом

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE193551T1 (de) 1991-03-18 2000-06-15 Scripps Research Inst Oligosaccharide als enzymsubstrate und - inhibitoren: verfahren und zusammensetzungen
US5770407A (en) * 1996-12-10 1998-06-23 The Scripps Research Institute Process for preparing nucleotide inhibitors of glycosyltransferases
CN101724075B (zh) 2001-10-10 2014-04-30 诺和诺德公司 肽的重构和糖缀合
US7226903B2 (en) * 2001-10-10 2007-06-05 Neose Technologies, Inc. Interferon beta: remodeling and glycoconjugation of interferon beta
WO2004035605A2 (fr) * 2002-10-16 2004-04-29 The Scripps Research Institute Synthese de glycoproteines
DK2144923T3 (da) 2007-04-03 2013-05-13 Biogenerix Ag Behandlingsfremgangsmåder under anvendelse af glycopegyleret g-csf
US8173597B2 (en) * 2007-11-09 2012-05-08 Baxter International Inc. Modified recombinant factor VIII and von Willebrand factor and methods of use
CA2768155C (fr) * 2009-06-16 2016-08-23 The University Of Bath Matieres et procedes lies a la glycosylation

Also Published As

Publication number Publication date
US9452223B2 (en) 2016-09-27
PL2442831T3 (pl) 2016-06-30
WO2010146362A3 (fr) 2011-06-30
JP2015187153A (ja) 2015-10-29
EP2442831B9 (fr) 2016-05-11
CA2768155A1 (fr) 2010-12-23
CN102481377A (zh) 2012-05-30
EP2442831A2 (fr) 2012-04-25
JP6091892B2 (ja) 2017-03-08
EP2442831B1 (fr) 2015-11-04
CN102481377B (zh) 2014-10-29
CA2768155C (fr) 2016-08-23
JP2012530119A (ja) 2012-11-29
WO2010146362A2 (fr) 2010-12-23
ES2560557T3 (es) 2016-02-19
US20120190631A1 (en) 2012-07-26

Similar Documents

Publication Publication Date Title
ZA201107702B (en) Composition and methods related to protein a(spa)variants
ZA201209561B (en) Compositions and methods related to protein a (spa) variants
IL252490A0 (en) Ceramic-ceramic bonding and related methods
ZA201200122B (en) Glucose-regulating polypeptides and methods of making and using same
IL215480A0 (en) Control of protein glycosylation and compositions and methods relating thereto
EP2547771A4 (fr) Production de protéines et de polypeptides
HK1173654A1 (zh) 治療化合物及相關的使用方法
EP2440241A4 (fr) Polypeptides d'hormone de croissance et leurs procédés de production et d'utilisation
IL216619A0 (en) Recombinant production of peptides
EP2495255A4 (fr) Forme glycosylée d'analogue du glp-1 antigénique
EP2655651A4 (fr) Procédé peu coûteux d'expression et purification de protéines recombinantes dans des plantes
IL215537A (en) Human recombinant alpha1-antitrapazine and a method for its production
IL216543A (en) Methods for enhancing production of human recombinant wild strain of beta-glucosidase
HK1169336A1 (en) Materials and methods relating to glycosylation of a therapeutic polypeptide
IL222714A0 (en) Preparation of polypeptides and salts thereof
ZA201209021B (en) Therapeutic peptide composition and method
HU0900706D0 (en) Preparation and application of hobby- creative auxiliary material
PL2411890T3 (pl) Interfejs dla systemu czujników planarnych i sposób sterowania nim
TWM365750U (en) Adhesive structure of breathable plaster
GB0906676D0 (en) Improvements in and relating to the consideration of evidence
GB0906275D0 (en) Improvements in and relating to the consideration of evidence