HK1166795A1 - 用於胸腺瘤治療的激酶抑制劑的用途 - Google Patents

用於胸腺瘤治療的激酶抑制劑的用途

Info

Publication number
HK1166795A1
HK1166795A1 HK12107532.6A HK12107532A HK1166795A1 HK 1166795 A1 HK1166795 A1 HK 1166795A1 HK 12107532 A HK12107532 A HK 12107532A HK 1166795 A1 HK1166795 A1 HK 1166795A1
Authority
HK
Hong Kong
Prior art keywords
thymoma
treatment
kinase inhibitor
kinase
inhibitor
Prior art date
Application number
HK12107532.6A
Other languages
English (en)
Inventor
．斯卡布裡
．帕恰裡尼
．喬梅伊
．拉弗蘭基
．科米斯
Original Assignee
內爾維阿諾醫學科學有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 內爾維阿諾醫學科學有限公司 filed Critical 內爾維阿諾醫學科學有限公司
Publication of HK1166795A1 publication Critical patent/HK1166795A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK12107532.6A 2009-03-20 2012-08-01 用於胸腺瘤治療的激酶抑制劑的用途 HK1166795A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09155745 2009-03-20
PCT/EP2010/053311 WO2010106028A1 (en) 2009-03-20 2010-03-15 Use of a kinase inhibitor for the treatment of thymoma

Publications (1)

Publication Number Publication Date
HK1166795A1 true HK1166795A1 (zh) 2012-11-09

Family

ID=42106701

Family Applications (1)

Application Number Title Priority Date Filing Date
HK12107532.6A HK1166795A1 (zh) 2009-03-20 2012-08-01 用於胸腺瘤治療的激酶抑制劑的用途

Country Status (7)

Country Link
US (1) US8580793B2 (zh)
EP (1) EP2408776B1 (zh)
JP (1) JP5650193B2 (zh)
CN (1) CN102356083B (zh)
ES (1) ES2445896T3 (zh)
HK (1) HK1166795A1 (zh)
WO (1) WO2010106028A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2660146T3 (es) * 2009-04-29 2018-03-21 Nerviano Medical Sciences S.R.L. Sales del inhibidor de cdk
WO2012101029A1 (en) * 2011-01-26 2012-08-02 Nerviano Medical Sciences S.R.L. Tricyclic derivatives, process for their preparation and their use as kinase inhibitors
ES2602791T3 (es) * 2011-01-26 2017-02-22 Nerviano Medical Sciences S.R.L. Derivados de pirrolo tricíclicos, proceso para su preparación y su uso como inhibidores de cinasa
CN107383019B (zh) * 2017-07-28 2019-10-15 江苏艾凡生物医药有限公司 吡唑并[4,3-h]喹唑啉类化合物及其用途
CN113811302B (zh) * 2019-05-08 2023-12-29 山东轩竹医药科技有限公司 激酶抑制剂的用途
KR20220164125A (ko) 2021-06-03 2022-12-13 한국과학기술원 흉선종의 진단, 예방, 또는 치료용 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1636236T3 (pl) * 2003-05-22 2014-02-28 Nerviano Medical Sciences Srl Pochodne pirazolochinazoliny, sposób ich wytwarzania oraz ich zastosowanie jako inhibitory kinaz
JP2005006532A (ja) * 2003-06-18 2005-01-13 Pharma Design Inc ヒトオーロラａ蛋白質に対する抗体及びその応用
FR2857363B1 (fr) * 2003-07-10 2007-09-07 Aventis Pharma Sa 4,5,6,7-tetrahydro-1h-pyrazolo[3,4-c] pyridines substituees compositions les contenant et utilisation
JP2007137856A (ja) * 2005-11-22 2007-06-07 Univ Nagoya オーロラａタンパク質の活性調節剤及びその利用
ES2390237T3 (es) 2006-02-10 2012-11-07 Nerviano Medical Sciences S.R.L. Combinaciones que comprenden un inhibidor de cdk y un anticuerpo anti-factor de crecimiento o un agente antimitótico
PE20080668A1 (es) * 2006-08-30 2008-07-17 Novartis Ag Compuestos heterociclicos como inhibidores de la cinasa-2 de proteina activada por cinasa de proteina activada por mitogeno
AU2008211172A1 (en) * 2007-01-30 2008-08-07 Biogen Idec Ma Inc. 1-H-pyrazolo(3,4B)pyrimidine derivatives and their use as modulators of mitotic kinases

Also Published As

Publication number Publication date
US8580793B2 (en) 2013-11-12
WO2010106028A1 (en) 2010-09-23
ES2445896T3 (es) 2014-03-05
EP2408776A1 (en) 2012-01-25
EP2408776B1 (en) 2014-01-08
CN102356083A (zh) 2012-02-15
JP5650193B2 (ja) 2015-01-07
JP2012520846A (ja) 2012-09-10
CN102356083B (zh) 2014-10-15
US20120077819A1 (en) 2012-03-29

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