HK1154910A1 - Tests to predict responsiveness of cancer patients to chemotherapy treatment options - Google Patents

Tests to predict responsiveness of cancer patients to chemotherapy treatment options

Info

Publication number
HK1154910A1
HK1154910A1 HK11109113.0A HK11109113A HK1154910A1 HK 1154910 A1 HK1154910 A1 HK 1154910A1 HK 11109113 A HK11109113 A HK 11109113A HK 1154910 A1 HK1154910 A1 HK 1154910A1
Authority
HK
Hong Kong
Prior art keywords
tests
cancer patients
treatment options
chemotherapy treatment
predict responsiveness
Prior art date
Application number
HK11109113.0A
Other languages
English (en)
Inventor
Steve Shak
Joffre B Baker
Carl Yoshizawa
Joseph Sparano
Robert Gary
Original Assignee
Genomic Health Inc
Aventis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomic Health Inc, Aventis Inc filed Critical Genomic Health Inc
Publication of HK1154910A1 publication Critical patent/HK1154910A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57415—Specifically defined cancers of breast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
HK11109113.0A 2008-05-12 2011-08-29 Tests to predict responsiveness of cancer patients to chemotherapy treatment options HK1154910A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5257308P 2008-05-12 2008-05-12
US5718208P 2008-05-29 2008-05-29
PCT/US2009/043667 WO2009140304A1 (fr) 2008-05-12 2009-05-12 Tests pour prédire une sensibilité de patients atteints de cancer à des options de traitement de chimiothérapie

Publications (1)

Publication Number Publication Date
HK1154910A1 true HK1154910A1 (en) 2012-05-04

Family

ID=41319028

Family Applications (2)

Application Number Title Priority Date Filing Date
HK11109113.0A HK1154910A1 (en) 2008-05-12 2011-08-29 Tests to predict responsiveness of cancer patients to chemotherapy treatment options
HK13107812.6A HK1180727A1 (en) 2008-05-12 2011-08-29 Tests to predict responsiveness of cancer patients to chemotherapy treatment options

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK13107812.6A HK1180727A1 (en) 2008-05-12 2011-08-29 Tests to predict responsiveness of cancer patients to chemotherapy treatment options

Country Status (7)

Country Link
US (1) US20090311702A1 (fr)
EP (5) EP2641977B1 (fr)
CA (1) CA2723972A1 (fr)
DK (2) DK2294215T3 (fr)
ES (2) ES2403220T3 (fr)
HK (2) HK1154910A1 (fr)
WO (1) WO2009140304A1 (fr)

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WO2006052862A1 (fr) * 2004-11-05 2006-05-18 Genomic Health, Inc. Prediction de reaction a la chimiotherapie au moyen de marqueurs d'expression genique
IL282783B2 (en) 2006-05-18 2023-09-01 Caris Mpi Inc A system and method for determining a personalized medical intervention for a disease stage
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
EP3075864A1 (fr) * 2008-10-14 2016-10-05 Caris MPI, Inc. Gène et protéine exprimées par des gènes cibles représentant des profils de biomarqueurs et ensembles de signature par type de tumeurs
GB2463401B (en) 2008-11-12 2014-01-29 Caris Life Sciences Luxembourg Holdings S A R L Characterizing prostate disorders by analysis of microvesicles
US20120041274A1 (en) 2010-01-07 2012-02-16 Myriad Genetics, Incorporated Cancer biomarkers
US8980564B2 (en) 2009-11-20 2015-03-17 The Governors Of The University Of Alberta Predictive markers for taxane responsiveness and methods of use thereof
US20130005597A1 (en) * 2009-12-18 2013-01-03 Rathmell W Kimryn Methods and compositions for analysis of clear cell renal cell carcinoma (ccrcc)
US20130011393A1 (en) * 2010-01-12 2013-01-10 Johnathan Mark Lancaster Bad pathway gene signature
KR20130056855A (ko) 2010-03-01 2013-05-30 카리스 라이프 사이언스 룩셈부르크 홀딩스 치료진단용 생물학적 지표들
AU2011237669B2 (en) 2010-04-06 2016-09-08 Caris Life Sciences Switzerland Holdings Gmbh Circulating biomarkers for disease
US20120053253A1 (en) 2010-07-07 2012-03-01 Myriad Genetics, Incorporated Gene signatures for cancer prognosis
WO2012030840A2 (fr) 2010-08-30 2012-03-08 Myriad Genetics, Inc. Signatures génétiques pour le diagnostic et le pronostic du cancer
WO2012097276A2 (fr) * 2011-01-13 2012-07-19 Expression Pathology, Inc. Dosage par srm/mrm de la protéine 11 de type bcl-2
WO2012145575A2 (fr) 2011-04-21 2012-10-26 Children's Hospital Medical Center Thérapie pour la leucémie
US10342767B2 (en) 2011-04-21 2019-07-09 Children's Hospital Medical Center Therapy for kinase-dependent malignancies
CN102312002A (zh) * 2011-09-20 2012-01-11 李艳 一种快速检测BRCA1基因mRNA表达量的试剂盒
WO2013130465A2 (fr) * 2012-02-27 2013-09-06 Genomic Health, Inc. Marqueurs d'expression génétique utilisés pour prédire l'efficacité d'un médicament antinéoplasique à base de platine
WO2013170174A1 (fr) * 2012-05-10 2013-11-14 H. Lee Moffitt Cancer Center And Research Institute, Inc. Méthode de diagnostic, de traitement et de détermination de la progression et de la survie de cellules cancéreuses à l'aide de la signature génique de l'antagoniste bcl-2 de la voie de la mort cellulaire (bad)
CN102965433A (zh) * 2012-09-29 2013-03-13 李艳 一种检测M BCR融合基因mRNA表达量的试剂盒
EP2920322B1 (fr) 2012-11-16 2023-01-11 Myriad Genetics, Inc. Signatures génétiques utilisées en vue du pronostic d'un cancer
WO2014092572A1 (fr) * 2012-12-12 2014-06-19 Universiteit Leiden Méthodes améliorées de traitement du cancer à l'aide d'un agent génotoxique
CA2912547A1 (fr) * 2013-07-03 2015-01-08 F. Hoffmann-La Roche Ag Expression genique a base d'arnm pour la personnalisation de la therapie anticancereuse d'un patient par un antagoniste de mdm2
US9657351B2 (en) 2013-12-06 2017-05-23 Hoffman-La Roche Inc. MRNA-based gene expression for personalizing patient cancer therapy with an MDM2 antagonist
CA2944401A1 (fr) * 2014-04-03 2015-10-08 Invictus Oncology Pvt. Ltd. Agents therapeutiques combinatoires supramoleculaires
CA2947624A1 (fr) 2014-05-13 2015-11-19 Myriad Genetics, Inc. Signatures genetiques utilisees en vue du pronostic d'un cancer
US20170079979A1 (en) * 2014-06-02 2017-03-23 Children's Hospital Medical Center Therapy for solid tumors
GB201501930D0 (en) * 2015-02-05 2015-03-25 Univ London Queen Mary Biomarkers for pancreatic cancer
US11136583B2 (en) 2017-01-10 2021-10-05 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
WO2019217581A2 (fr) * 2018-05-11 2019-11-14 Baylor College Of Medicine Perte de mutl prédisant la sensibilité à des inhibiteurs de cdk4/6 dans le cancer
US20210317535A1 (en) * 2018-08-29 2021-10-14 The Regents Of The University Of Michigan Methods of determining treatment consisting of radiation therapy and/or alkylating chemotherapy in patients suffering from cancer
CN109439755A (zh) * 2018-11-30 2019-03-08 广东腾飞基因科技股份有限公司 一种用于检测乳腺癌相关基因表达水平的试剂盒

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Also Published As

Publication number Publication date
EP2641978A1 (fr) 2013-09-25
HK1180727A1 (en) 2013-10-25
CA2723972A1 (fr) 2009-11-19
ES2482692T3 (es) 2014-08-04
EP2641977B1 (fr) 2014-09-03
EP2294215A4 (fr) 2011-06-29
EP2641977A1 (fr) 2013-09-25
DK2294215T3 (da) 2013-04-22
EP2568053A1 (fr) 2013-03-13
EP2294215B1 (fr) 2013-01-16
EP2294215A1 (fr) 2011-03-16
DK2568053T3 (da) 2014-07-21
WO2009140304A1 (fr) 2009-11-19
ES2403220T3 (es) 2013-05-16
US20090311702A1 (en) 2009-12-17
EP2607497A1 (fr) 2013-06-26
EP2568053B1 (fr) 2014-04-16
EP2607497B1 (fr) 2014-10-01

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