HK1136848B - 增强對哺乳動物細胞基因表達的調節用雙鏈rna輸送的組合物 - Google Patents

增强對哺乳動物細胞基因表達的調節用雙鏈rna輸送的組合物 Download PDF

Info

Publication number
HK1136848B
HK1136848B HK10104471.8A HK10104471A HK1136848B HK 1136848 B HK1136848 B HK 1136848B HK 10104471 A HK10104471 A HK 10104471A HK 1136848 B HK1136848 B HK 1136848B
Authority
HK
Hong Kong
Prior art keywords
cholesteryl
sirna
spermidine
cholesterol
linked
Prior art date
Application number
HK10104471.8A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1136848A1 (zh
Inventor
Ahmadian Mohammad
Cui Kunyuan
Chen Lishan
Chen Quay Shu-Chih
E. Jr. Houston Michael
Original Assignee
Mdrna, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mdrna, Inc. filed Critical Mdrna, Inc.
Publication of HK1136848A1 publication Critical patent/HK1136848A1/zh
Publication of HK1136848B publication Critical patent/HK1136848B/zh

Links

HK10104471.8A 2004-04-20 2010-05-07 增强對哺乳動物細胞基因表達的調節用雙鏈rna輸送的組合物 HK1136848B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56454304P 2004-04-20 2004-04-20
US564543P 2004-04-20

Publications (2)

Publication Number Publication Date
HK1136848A1 HK1136848A1 (zh) 2010-07-09
HK1136848B true HK1136848B (zh) 2014-08-01

Family

ID=

Similar Documents

Publication Publication Date Title
EP2145957B1 (en) Compositions for enhancing delivery of double-stranded RNA to regulate gene expression in mammalian cells
CN104673798B (zh) UsiRNA复合物
US12091661B2 (en) Organic compositions to treat HSF1-related diseases
JP6060178B2 (ja) 高効率のナノ粒子型二本鎖オリゴｒｎａ構造体およびその製造方法
AU2014282666A1 (en) Double-stranded antisense nucleic acid with exon-skipping effect
IL194419A (en) Dsrna to inhibit the expression of a 5eg gene in a human cell, a pharmaceutical compound containing it, a vector method
KR20220008383A (ko) 베타-ＥＮａＣ-관련 질환을 치료하기 위한 유기 조성물
JP2022517742A (ja) Ｈｍｇｂ１発現を阻害するための組成物及び方法
KR20200014320A (ko) Apcs의 발현을 억제하는 핵산