HK1136816A - 氟苯尼考及其类似物的水溶性前药 - Google Patents

氟苯尼考及其类似物的水溶性前药 Download PDF

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Publication number
HK1136816A
HK1136816A HK10100550.0A HK10100550A HK1136816A HK 1136816 A HK1136816 A HK 1136816A HK 10100550 A HK10100550 A HK 10100550A HK 1136816 A HK1136816 A HK 1136816A
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HK
Hong Kong
Prior art keywords
florfenicol
analogs
water
prodrug
prodrugs
Prior art date
Application number
HK10100550.0A
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English (en)
Inventor
Tomasz W. Glinka
Jason Zhang
Original Assignee
Schering-Plough Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering-Plough Ltd. filed Critical Schering-Plough Ltd.
Publication of HK1136816A publication Critical patent/HK1136816A/zh

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Abstract

本发明公开了氟苯尼考和/或氟苯尼考类似物的某些新型前药，包括氟苯尼考及其类似物的药学上可接受的盐的盐类前药，包括含氮酯仲醇一组氟苯尼考及其类似物，和其药学上可接受的盐、包含它们的组合物的方法，及将它们施用于对象。在特定实施例中，该前药具有充分的水溶性，以服务的水溶性前药所需的功能氟苯尼考的水溶性前药或氟苯尼考类似物。某个子类化合物还具有水解稳定性，需要在患者的系统中将前药维持在溶液中，直到适当的条件存在，当前药可水解，释放氟苯尼考或氟苯尼考类似物中。
HK10100550.0A 2006-12-13 2007-12-11 氟苯尼考及其类似物的水溶性前药 HK1136816A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US874864P 2006-12-13

Publications (1)

Publication Number Publication Date
HK1136816A true HK1136816A (zh) 2010-07-09

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