HK1122988A1 - Proteasome inhibitors and uses thereof - Google Patents

Proteasome inhibitors and uses thereof

Info

Publication number
HK1122988A1
HK1122988A1 HK09100183.8A HK09100183A HK1122988A1 HK 1122988 A1 HK1122988 A1 HK 1122988A1 HK 09100183 A HK09100183 A HK 09100183A HK 1122988 A1 HK1122988 A1 HK 1122988A1
Authority
HK
Hong Kong
Prior art keywords
proteasome inhibitors
proteasome
inhibitors
Prior art date
Application number
HK09100183.8A
Other languages
English (en)
Inventor
Jack Arbiser
Original Assignee
Jack Arbiser
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jack Arbiser filed Critical Jack Arbiser
Publication of HK1122988A1 publication Critical patent/HK1122988A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Hydrogenated Pyridines (AREA)
HK09100183.8A 2005-05-20 2009-01-08 Proteasome inhibitors and uses thereof HK1122988A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68338505P 2005-05-20 2005-05-20
PCT/US2006/019591 WO2006127525A2 (en) 2005-05-20 2006-05-19 Proteasome inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
HK1122988A1 true HK1122988A1 (en) 2009-06-05

Family

ID=37452658

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09100183.8A HK1122988A1 (en) 2005-05-20 2009-01-08 Proteasome inhibitors and uses thereof

Country Status (10)

Country Link
US (1) US8809283B2 (xx)
EP (2) EP1895971A4 (xx)
JP (2) JP5745743B2 (xx)
CN (1) CN101222900B (xx)
AU (1) AU2006251655B2 (xx)
CA (1) CA2609213C (xx)
ES (1) ES2891179T3 (xx)
HK (1) HK1122988A1 (xx)
IL (1) IL187463A (xx)
WO (1) WO2006127525A2 (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009026579A1 (en) * 2007-08-23 2009-02-26 Cornell Research Foundation, Inc. Proteasome inhibitors and their use in treating pathogen infection and cancer
FR2926955B1 (fr) 2008-02-01 2012-07-20 Agronomique Inst Nat Rech Procede de preparation d'acides dicafeoylquiniques et leur utilisation dans la lutte contre les pucerons
WO2013025986A2 (en) 2011-08-17 2013-02-21 Basf Corporation Marine based cosmetic active ingredients and use thereof
PT2841075T (pt) 2012-04-26 2020-06-25 Massachusetts Gen Hospital Agentes e métodos para tratamento e prevenção de queratose seborreica
CN103570806B (zh) * 2012-07-26 2020-04-07 圣特莱国际公司 多肽环氧酮化合物
WO2014175518A1 (ko) * 2013-04-23 2014-10-30 한국식품연구원 마테 추출물을 유효성분으로 포함하는 통증의 완화, 예방 또는 치료용 조성물 및 시료의 통증 완화, 예방 또는 치료 효능에 대한 평가방법
KR101483990B1 (ko) 2013-04-23 2015-01-20 한국식품연구원 시료의 통증 완화, 예방 또는 치료 효능에 대한 평가방법
US10508309B2 (en) 2013-05-17 2019-12-17 The General Hospital Corporation Methods for detecting and treating variants of seborrheic keratoses
GB201317286D0 (en) * 2013-09-30 2013-11-13 Calscience Internat Ltd Composition and Use
CN104546819A (zh) * 2013-10-09 2015-04-29 中国医学科学院药物研究所 二咖啡酰奎宁酸在治疗系统性自身免疫性疾病中的用途
WO2015103012A1 (en) * 2013-12-31 2015-07-09 Applied Biology, Inc. Methods and compositions for administering a specific wavelength phototherapy
GB201502268D0 (en) 2015-02-11 2015-04-01 Calscience Internat Ltd Dental composition and use
CN108883081A (zh) * 2015-11-06 2018-11-23 阿克西制药有限公司 蛋白酶体抑制剂治疗眼部疾病的用途
EP3585809A4 (en) 2017-01-30 2021-02-24 Western New England University THIOLISOMERASE INHIBITORS AND USES THEREOF
WO2019089942A1 (en) * 2017-11-02 2019-05-09 Rick Coulon Formulations for use in the transdermal delivery of proteasome inhibitors
FR3080030B1 (fr) * 2018-04-13 2020-04-24 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Utilisation d’une nouvelle composition pour empecher ou ralentir l’apparition des signes inesthetiques lies a la presence de sebum en exces
FR3080032B1 (fr) * 2018-04-13 2020-04-17 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Utilisation d'une nouvelle composition pour empecher ou ralentir l'apparition de signes d'inflammation

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034412A (en) * 1987-03-17 1991-07-23 Merrell Dow Pharmacueticals Inc. Method of inhibiting interleukin-1 release
DE69031913T2 (de) 1989-07-14 1998-07-09 Biodor Us Holding Corp Antivirale mittel
US6355684B1 (en) * 1990-10-11 2002-03-12 Meryl J. Squires Antimicrobial treatment for herpes simplex virus and other infectious diseases
EP0582147A3 (en) 1992-08-03 1994-08-24 Nestle Sa Anti-urease cosmetic or dermatologic composition
AU7018794A (en) 1993-05-17 1994-12-12 Omega Pharmaceuticals, Inc. Methods for treating pathologies
US5811101A (en) * 1997-04-29 1998-09-22 Waltman Pharmaceuticals Incorporated Composition for treating acne
ES2172297T3 (es) * 1998-01-26 2002-09-16 Ciba Sc Holding Ag Aumento de peso molecular y estabilizacion de policondensados con diepoxidos de aminas impedidas estericamente.
US5972993A (en) * 1998-03-20 1999-10-26 Avon Products, Inc. Composition and method for treating rosacea and sensitive skin with free radical scavengers
US6632459B2 (en) * 2000-12-11 2003-10-14 Nutricia N.V. Chlorogenic acid and an analog thereof for immune system stimulation
US7381427B2 (en) * 2001-02-09 2008-06-03 Mickey Miller Seborrheic keratosis treatment
DE10121252A1 (de) 2001-04-30 2002-11-07 Christos C Zouboulis Behandlung der Akne
US8728445B2 (en) * 2001-05-01 2014-05-20 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Sciences Hydrogel Compositions
US6464025B1 (en) * 2001-05-15 2002-10-15 Crown Equipment Corporation Coast control for walkie/rider pallet truck
EP1260212A1 (de) * 2001-05-21 2002-11-27 Cognis France S.A. Kosmetische Mittel
WO2003000634A1 (en) 2001-06-20 2003-01-03 The Government Of The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services Vitamin d receptor antagonists and related compositions and methods of use
US20030105031A1 (en) * 2001-11-06 2003-06-05 Rosenbloom Richard A. Methods for the treatment of skin disorders
US7217853B2 (en) * 2002-05-24 2007-05-15 Corium International, Inc. Composition for cushions, wound dressings and other skin-contacting products
US20040156873A1 (en) * 2003-02-10 2004-08-12 Gupta Shyam K. Topically Bioavailable Acne and Rosacea Treatment Compositions
US20040243042A1 (en) 2003-05-20 2004-12-02 Lipman Roger D. A. Facial masks for managing skin wounds
US20050014637A1 (en) * 2003-06-04 2005-01-20 Duijghuisen Henricus Petrus Bernardus Polyether polyol composition
DE10336883A1 (de) * 2003-08-08 2005-03-10 Basf Ag Kunststoff, insbesondere Polyurethan enthaltend ein sterisch gehindertes, verestertes Amin
CN1863830B (zh) * 2003-10-07 2011-04-20 陶氏环球技术公司 用于空气骤冷吹塑薄膜的聚丙烯组合物
NZ544247A (en) 2004-12-22 2007-06-29 Omj Ireland Ltd Phototherapy using psoralen derivatives and a UVB absorber
DE602005022616D1 (de) * 2004-12-22 2010-09-09 Basf Se Mittel gegen radikale

Also Published As

Publication number Publication date
ES2891179T3 (es) 2022-01-26
IL187463A0 (en) 2008-03-20
US8809283B2 (en) 2014-08-19
AU2006251655A1 (en) 2006-11-30
CA2609213C (en) 2016-08-23
JP5745743B2 (ja) 2015-07-08
JP2013177463A (ja) 2013-09-09
US20070004647A1 (en) 2007-01-04
CN101222900B (zh) 2013-02-13
EP3087969A1 (en) 2016-11-02
IL187463A (en) 2015-08-31
EP1895971A2 (en) 2008-03-12
CN101222900A (zh) 2008-07-16
WO2006127525A3 (en) 2007-03-15
EP3087969B1 (en) 2021-06-30
JP2008540682A (ja) 2008-11-20
EP1895971A4 (en) 2012-08-08
AU2006251655B2 (en) 2012-10-11
CA2609213A1 (en) 2006-11-30
WO2006127525A2 (en) 2006-11-30

Similar Documents

Publication Publication Date Title
HK1122988A1 (en) Proteasome inhibitors and uses thereof
IL228770A0 (en) processes and intermediates
EP1742627A4 (en) PDE4B HEMMER AND ITS USE
EP1812049A4 (en) KALLIKREIN INHIBITORS AND USES THEREOF
EP1920216A4 (en) SIGNALING AND LOCATION ORIENTATION
IL179398A0 (en) Dpp-ib inhibitors
ZA200810323B (en) Fkbp-l and uses thereof
IL192134A0 (en) Soft protease inhibitors and pro-soft forms thereof
SI2064327T1 (sl) DBAIT in njegova uporaba
IL179497A0 (en) Carboranylporphyrins and uses thereof
ZA200804299B (en) 3-amino-2-arylpropyl azaindoles and uses thereof
HK1133552A1 (en) Carboranylporphyrins and uses thereof
IL189252A0 (en) Dihydroxyanthraquinones and their use
EP1921066A4 (en) PYRIDYLPHENOL COMPOUND AND USE THEREOF
IL181819A0 (en) Enzyme inhibitors and uses thereof
IL180365A0 (en) Carboranylporphyrins and uses thereof
IL185223A0 (en) Compounds and uses thereof
GB0421355D0 (en) Inhibitors
GB0520935D0 (en) Integrated processor-template-system and project
GB0421356D0 (en) Inhibitors
GB0516967D0 (en) Inhibitors
GB0505620D0 (en) Methods and materials therefor
GB0517239D0 (en) Geogrotren-mk1-system and project
GB0517240D0 (en) Chronorotron mk1-system and project
GB0522259D0 (en) e-s-spi-l-d-film-cinema-back-engineering armageddon-system and project