HK1052872A1 - 微团 - Google Patents

微团 Download PDF

Info

Publication number
HK1052872A1
HK1052872A1 HK03105085.2A HK03105085A HK1052872A1 HK 1052872 A1 HK1052872 A1 HK 1052872A1 HK 03105085 A HK03105085 A HK 03105085A HK 1052872 A1 HK1052872 A1 HK 1052872A1
Authority
HK
Hong Kong
Prior art keywords
micelles
pharmaceutical compositions
stereoisomers
compound
methods
Prior art date
Application number
HK03105085.2A
Other languages
English (en)
Chinese (zh)
Inventor
Mcshane James
Arens Tori
Kaneko Kazuhiro
Watanabe Tomohiro
Ashizawa Kazuhide
Original Assignee
Eisai R&D Management Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Management Co., Ltd. filed Critical Eisai R&D Management Co., Ltd.
Publication of HK1052872A1 publication Critical patent/HK1052872A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK03105085.2A 2000-02-18 2001-02-20 微团 HK1052872A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18376800P 2000-02-18 2000-02-18
US60/183,768 2000-02-18
PCT/US2001/005297 WO2001060382A1 (en) 2000-02-18 2001-02-20 Micelles

Publications (1)

Publication Number Publication Date
HK1052872A1 true HK1052872A1 (zh) 2003-10-03

Family

ID=22674206

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03105085.2A HK1052872A1 (zh) 2000-02-18 2001-02-20 微团

Country Status (10)

Country Link
US (3) US6906042B2 (https=)
EP (2) EP2452684B1 (https=)
JP (2) JP4959085B2 (https=)
KR (1) KR100841813B1 (https=)
AU (2) AU2001238507C9 (https=)
CA (1) CA2400371C (https=)
ES (1) ES2664818T3 (https=)
HK (1) HK1052872A1 (https=)
IL (2) IL151314A0 (https=)
WO (1) WO2001060382A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030130212A1 (en) * 1999-01-14 2003-07-10 Rossignol Daniel P. Administration of an anti-endotoxin drug by intravenous infusion
AU2001238507C9 (en) * 2000-02-18 2005-07-07 Eisai R&D Management Co., Ltd. Micelles
US7759323B2 (en) * 2001-05-22 2010-07-20 Eisai R & D Management Co., Ltd. Highly purified antiendotoxin compound
US7727974B2 (en) 2001-08-10 2010-06-01 Eisai R & D Management Co., Ltd. Methods of reducing the severity of mucositis
EP1420798A4 (en) * 2001-08-10 2007-07-25 Eisai Co Ltd TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS RELATED TO HEAT SHOCK PROTEIN
US20040005351A1 (en) * 2002-03-29 2004-01-08 Kwon Glen S. Polymeric micelle formulations of hydrophobic compounds and methods
US20040116360A1 (en) * 2002-10-15 2004-06-17 Kwon Glen S. Encapsulation and deaggregation of polyene antibiotics using poly(ethylene glycol)-phospholipid micelles
EP1661556A4 (en) * 2003-08-20 2010-05-19 Ajinomoto Kk MEDICAL PREPARATION WITH IMPROVED RESOLUTION CHARACTERISTICS
ATE446581T1 (de) * 2004-03-12 2009-11-15 Trinity College Dublin Magnetoresistives medium
CA2620027A1 (en) * 2005-08-31 2007-03-08 Eisai R & D Management Co., Ltd. Process for production of lipid a analogue
US20070197486A1 (en) * 2005-12-20 2007-08-23 Verus Pharmaceuticals, Inc. Methods and systems for the delivery of corticosteroids
US20070160542A1 (en) * 2005-12-20 2007-07-12 Verus Pharmaceuticals, Inc. Methods and systems for the delivery of corticosteroids having an enhanced pharmacokinetic profile
US20070249572A1 (en) * 2005-12-20 2007-10-25 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids
US20070178049A1 (en) * 2005-12-20 2007-08-02 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids having an enhanced pharmacokinetic profile
US20070185066A1 (en) * 2005-12-20 2007-08-09 Verus Pharmaceuticals, Inc. Systems and methods for the delivery of corticosteroids
JP2009526858A (ja) * 2006-02-15 2009-07-23 ティカ レーケメデル アーベー コルチコステロイド溶液を製造する方法
BR112014024139A8 (pt) 2012-03-28 2018-01-16 Univ Maryland administração de eritoran ou sais farmaceuticamente aceitáveis do mesmo para tratar infecções de ortomixovírus
JP7069120B2 (ja) 2016-09-16 2022-05-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 エボラ（ｅｂｏｌａ）及びマールブルク（ｍａｒｂｕｒｇ）病を治療するためのｔｌｒ４拮抗薬としてのエリトランの使用方法
US10765633B2 (en) 2018-12-17 2020-09-08 Eisai R&D Management Co., Ltd Formulation comprising liposomes
US11198831B2 (en) 2019-01-31 2021-12-14 Kvi Llc Lubricant for a device
WO2021207218A1 (en) 2020-04-06 2021-10-14 Eisai R&D Management Co., Ltd. Treatment of nidovirales infection with eritoran

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530113A (en) 1991-10-11 1996-06-25 Eisai Co., Ltd. Anti-endotoxin compounds
US6417172B1 (en) 1995-06-05 2002-07-09 Eisai Co., Ltd. Prevention and treatment of pulmonary bacterial infection or symptomatic pulmonary exposure to endotoxin by inhalation of antiendotoxin drugs
US5681824A (en) 1995-06-05 1997-10-28 Eisai Co., Ltd. Substituted liposaccharides useful in the treatment and prevention of endotoxemia
US5952309A (en) * 1995-09-29 1999-09-14 Eisai Company, Ltd. Method for treating alcoholic liver disease
DK0909562T3 (da) * 1996-07-03 2005-08-22 Eisai Co Ltd Injektionspræparat indeholdende en lipid A analog og fremgangsmåde til fremstilling deraf
JP4326030B2 (ja) * 1996-07-03 2009-09-02 エーザイ・アール・アンド・ディー・マネジメント株式会社 リピッドａ類縁体含有注射用製剤及びその製造方法
US6495532B1 (en) 1997-03-19 2002-12-17 Sky High, Llc Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof
AU7799198A (en) 1997-05-23 1998-12-21 Eisai Co. Ltd. Method for preparing pharmaceutical formulation
US6437006B1 (en) 1999-09-27 2002-08-20 American Cyanamid Company Pharmaceutical carrier formulation
AU2001229479A1 (en) 2000-01-14 2001-07-24 Eisai Co. Ltd. Prevention and treatment of endotoxemia and related complications associated with surgery
AU2001238507C9 (en) * 2000-02-18 2005-07-07 Eisai R&D Management Co., Ltd. Micelles
US6861512B2 (en) 2000-03-01 2005-03-01 Eisai Co., Ltd. Separation of olefinic isomers
US20030105033A1 (en) 2000-06-09 2003-06-05 Rossignol Daniel P. Administration of an anti-endotoxin drug by bolus or intermittent intravenous infusion
JP4179881B2 (ja) 2000-12-06 2008-11-12 エーザイ株式会社 凍結乾燥ケークの抵抗を測定するためのシステム及び方法
CA2446356C (en) 2001-05-09 2012-07-10 The Regents Of The University Of Michigan Use of compositions for treating rosacea
US7727974B2 (en) 2001-08-10 2010-06-01 Eisai R & D Management Co., Ltd. Methods of reducing the severity of mucositis
BRPI0408077A (pt) 2003-03-05 2006-02-14 Eisai Co Ltd composições e métodos para prevenção e tratamento de doenças relacionadas com endotoxina e condições

Also Published As

Publication number Publication date
AU3850701A (en) 2001-08-27
AU2001238507C9 (en) 2005-07-07
EP2452684A2 (en) 2012-05-16
IL151314A (en) 2007-06-03
US7989432B2 (en) 2011-08-02
EP2452684B1 (en) 2018-01-24
US20090136564A1 (en) 2009-05-28
AU2001238507C1 (en) 2005-02-24
IL151314A0 (en) 2003-04-10
EP2452684A3 (en) 2012-10-03
CA2400371A1 (en) 2001-08-23
KR20030011774A (ko) 2003-02-11
ES2664818T3 (es) 2018-04-23
JP2012116860A (ja) 2012-06-21
WO2001060382A1 (en) 2001-08-23
US20050181039A1 (en) 2005-08-18
KR100841813B1 (ko) 2008-06-26
US7390793B2 (en) 2008-06-24
EP1274443A4 (en) 2008-12-31
CA2400371C (en) 2009-12-08
JP4959085B2 (ja) 2012-06-20
JP2003522797A (ja) 2003-07-29
US20030216331A1 (en) 2003-11-20
US6906042B2 (en) 2005-06-14
AU2001238507B2 (en) 2004-04-22
EP1274443A1 (en) 2003-01-15
EP1274443B1 (en) 2017-05-10

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