HK1048828A1 - 可令生產優化的核酸構造 - Google Patents

可令生產優化的核酸構造

Info

Publication number
HK1048828A1
HK1048828A1 HK03100852.4A HK03100852A HK1048828A1 HK 1048828 A1 HK1048828 A1 HK 1048828A1 HK 03100852 A HK03100852 A HK 03100852A HK 1048828 A1 HK1048828 A1 HK 1048828A1
Authority
HK
Hong Kong
Prior art keywords
products
nucleic acid
acid construct
optimized production
optimized
Prior art date
Application number
HK03100852.4A
Other languages
English (en)
Inventor
A Treco Douglas
F Concino Michael
J Duguay Stephen
Original Assignee
Transkaryotic Therapies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transkaryotic Therapies Inc filed Critical Transkaryotic Therapies Inc
Publication of HK1048828A1 publication Critical patent/HK1048828A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK03100852.4A 1999-11-19 2003-02-06 可令生產優化的核酸構造 HK1048828A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16650899P 1999-11-19 1999-11-19
PCT/US2000/031634 WO2001036643A1 (en) 1999-11-19 2000-11-17 Nucleic acid construct for optimized production of products

Publications (1)

Publication Number Publication Date
HK1048828A1 true HK1048828A1 (zh) 2003-04-17

Family

ID=22603611

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03100852.4A HK1048828A1 (zh) 1999-11-19 2003-02-06 可令生產優化的核酸構造

Country Status (10)

Country Link
US (1) US7229793B1 (zh)
EP (1) EP1234038A1 (zh)
JP (1) JP2003514532A (zh)
AU (1) AU784477B2 (zh)
CA (1) CA2391906A1 (zh)
HK (1) HK1048828A1 (zh)
IL (1) IL149679A0 (zh)
MX (1) MXPA02005014A (zh)
TW (2) TWI284132B (zh)
WO (1) WO2001036643A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
US8129504B2 (en) 2001-08-30 2012-03-06 Biorexis Technology, Inc. Oral delivery of modified transferrin fusion proteins
WO2004078777A2 (en) * 2003-03-04 2004-09-16 Biorexis Pharmaceutical Corporation Dipeptidyl-peptidase protected proteins
PT2038423E (pt) * 2006-06-21 2013-03-27 Biocon Ltd Método de produção de um polipéptido biologicamente activo possuindo actividade insulinotrópica
JP5102833B2 (ja) 2006-07-24 2012-12-19 バイオレクシス ファーマシューティカル コーポレーション エキセンディン融合タンパク質
WO2008082821A1 (en) * 2006-11-28 2008-07-10 University Of Southern California Method for promoting wound healing
US7829664B2 (en) 2007-06-01 2010-11-09 Boehringer Ingelheim International Gmbh Modified nucleotide sequence encoding glucagon-like peptide-1 (GLP-1), nucleic acid construct comprising same for production of glucagon-like peptide-1 (GLP-1), human cells comprising said construct and insulin-producing constructs, and methods of use thereof
CA2981517A1 (en) * 2015-04-01 2016-10-06 The Scripps Research Institute Methods and compositions related to gpcr agonist polypeptides

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU85269A1 (fr) 1984-03-26 1985-10-14 Techland S A Composes nouveaux de somatostatine,procede pour leur synthese,preparation a usage veterinaire contenant lesdits composes et procede pour le traitement d'animaux
GB8412517D0 (en) * 1984-05-16 1984-06-20 Nagai K Recombinant fusion proteins
US5118666A (en) * 1986-05-05 1992-06-02 The General Hospital Corporation Insulinotropic hormone
ATE164852T1 (de) * 1990-01-24 1998-04-15 Douglas I Buckley Glp-1-analoga verwendbar in der diabetesbehandlung
SK60893A3 (en) 1990-12-13 1993-10-06 Upjohn Co Fusion polypeptides
US5641670A (en) * 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
PT101031B (pt) * 1991-11-05 2002-07-31 Transkaryotic Therapies Inc Processo para o fornecimento de proteinas por terapia genetica
DK36392D0 (da) * 1992-03-19 1992-03-19 Novo Nordisk As Anvendelse af kemisk forbindelse
US6531124B1 (en) * 1992-07-10 2003-03-11 Transkaryotic Therapies, Inc. In vivo production and delivery of insulinotropin for gene therapy
JP3578787B2 (ja) * 1993-05-14 2004-10-20 ラホヤ インスティチュート フォア アレルギー アンド イムノロジー 生物学的に活性なポリペプチドの組換え製造方法
AU691189B2 (en) * 1993-06-21 1998-05-14 Genentech Inc. Process for producing relaxin
JPH0750969A (ja) * 1993-08-12 1995-02-28 Koji Higashiyama 針外し具
US6037145A (en) 1994-09-07 2000-03-14 Suntory Limited Process for production of protein
AT404838B (de) * 1995-11-24 1999-03-25 Immuno Ag Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen
WO1997029180A1 (en) 1996-02-06 1997-08-14 Eli Lilly And Company Diabetes therapy
CA2198966C (en) * 1996-03-04 2011-06-21 Yuji Suzuki Method for cleaving chimeric protein using processing enzyme
WO1998037910A1 (en) * 1997-03-02 1998-09-03 Emory University Peptide inhbitors of propeptide/prohormone convertases
JP2001525371A (ja) 1997-12-05 2001-12-11 イーライ・リリー・アンド・カンパニー Ｇｌｐ−１製剤

Also Published As

Publication number Publication date
MXPA02005014A (es) 2003-02-27
TW200538547A (en) 2005-12-01
JP2003514532A (ja) 2003-04-22
US7229793B1 (en) 2007-06-12
TWI284132B (en) 2007-07-21
AU784477B2 (en) 2006-04-13
AU1619801A (en) 2001-05-30
EP1234038A1 (en) 2002-08-28
CA2391906A1 (en) 2001-05-25
WO2001036643A1 (en) 2001-05-25
IL149679A0 (en) 2002-11-10

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