HK1045323A1 - Bioreactor design and process for engineering tissue from cells. - Google Patents

Bioreactor design and process for engineering tissue from cells.

Info

Publication number
HK1045323A1
HK1045323A1 HK02106718A HK02106718A HK1045323A1 HK 1045323 A1 HK1045323 A1 HK 1045323A1 HK 02106718 A HK02106718 A HK 02106718A HK 02106718 A HK02106718 A HK 02106718A HK 1045323 A1 HK1045323 A1 HK 1045323A1
Authority
HK
Hong Kong
Prior art keywords
inlet
hollow
fibers
compartment
bioreactor
Prior art date
Application number
HK02106718A
Other languages
English (en)
Inventor
Jeffrey M Macdonald
Stephen P Wolfe
Original Assignee
Univ Or North Carolina At Chap
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Or North Carolina At Chap filed Critical Univ Or North Carolina At Chap
Publication of HK1045323A1 publication Critical patent/HK1045323A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/40—Manifolds; Distribution pieces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HK02106718A 1999-06-03 2002-09-13 Bioreactor design and process for engineering tissue from cells. HK1045323A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13759499P 1999-06-03 1999-06-03
PCT/US2000/015524 WO2000075275A2 (en) 1999-06-03 2000-06-05 Bioreactor design and process for engineering tissue from cells

Publications (1)

Publication Number Publication Date
HK1045323A1 true HK1045323A1 (en) 2002-11-22

Family

ID=22478171

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02106718A HK1045323A1 (en) 1999-06-03 2002-09-13 Bioreactor design and process for engineering tissue from cells.

Country Status (10)

Country Link
EP (1) EP1185612B1 (xx)
JP (1) JP4656789B2 (xx)
AT (1) ATE274571T1 (xx)
AU (1) AU780160B2 (xx)
CA (1) CA2376039A1 (xx)
DE (1) DE60013277T2 (xx)
ES (1) ES2226850T3 (xx)
HK (1) HK1045323A1 (xx)
WO (1) WO2000075275A2 (xx)
ZA (1) ZA200109939B (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040152149A1 (en) * 2002-10-31 2004-08-05 Reid Lola M. Textiles for use in bioreactors for expansion and maintenance of cells
US8143337B1 (en) 2005-10-18 2012-03-27 The Ohio State University Method of preparing a composite with disperse long fibers and nanoparticles
EP1941537A4 (en) * 2005-10-20 2010-03-31 Univ Ohio State CONTRIBUTION OF MEDICAMENT AND GENES BY CELLULAR PATCH TO NANOBUSES AND POLYMER NANOPOINTES
JP2010519936A (ja) * 2007-03-05 2010-06-10 カリディアンビーシーティー、インコーポレーテッド 中空繊維バイオリアクター内における細胞の動きを制御する方法
CA2680130C (en) 2007-03-05 2016-01-12 Caridianbct, Inc. Cell expansion system and methods of use
WO2008128165A2 (en) * 2007-04-13 2008-10-23 Caridianbct, Inc. Cell expansion system and methods of use
US8691565B2 (en) 2008-03-05 2014-04-08 Terumo Bct, Inc. Method of reseeding adherent cells grown in a hollow fiber bioreactor system
US8507568B2 (en) 2008-05-28 2013-08-13 The Ohio State University Suspension polymerization and foaming of water containing activated carbon-nano/microparticulate polymer composites
AU2010256745A1 (en) * 2009-06-02 2012-01-19 Coastal Waters Biotechnology Group, Llc Systems and methods for cultivating, harvesting and processing biomass
DE102009039554A1 (de) * 2009-09-07 2011-03-10 Phytolutions Gmbh Verfahren zum Ernten von Algen aus einer Algensuspension, erstes, zweites und drittes Algensuspensionskonzentrat sowie erstes, zweites und drittes Nährflüssigkeitsfiltrat
US9057045B2 (en) 2009-12-29 2015-06-16 Terumo Bct, Inc. Method of loading and distributing cells in a bioreactor of a cell expansion system
EP2625263B1 (en) 2010-10-08 2020-03-11 Terumo BCT, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
EP2885393A1 (en) 2012-08-20 2015-06-24 Terumo BCT, Inc. Method of loading and distributing cells in a bioreactor of a cell expansion system
JP6633522B2 (ja) 2013-11-16 2020-01-22 テルモ ビーシーティー、インコーポレーテッド バイオリアクターにおける細胞増殖
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
US10077421B2 (en) 2014-04-24 2018-09-18 Terumo Bct, Inc. Measuring flow rate
JP6830059B2 (ja) 2014-09-26 2021-02-17 テルモ ビーシーティー、インコーポレーテッド スケジュール化された細胞フィーディング
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
EP3464565A4 (en) 2016-05-25 2020-01-01 Terumo BCT, Inc. CELL EXPANSION
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
JP7118059B2 (ja) * 2016-11-02 2022-08-15 イー・エム・デイー・ミリポア・コーポレイシヨン 細胞培養液からマイクロキャリアを分離するための容器
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537860A (en) * 1982-12-08 1985-08-27 Monsanto Company Static cell culture maintenance system
US4833083A (en) * 1987-05-26 1989-05-23 Sepragen Corporation Packed bed bioreactor
US5015585A (en) * 1988-02-23 1991-05-14 Robinson James R Method and apparatus for culturing and diffusively oxygenating cells on isotropic membranes
FR2660323B1 (fr) * 1990-03-30 1992-07-24 Bertin & Cie Dispositif de culture cellulaire.
IT1295621B1 (it) * 1997-10-16 1999-05-14 Braun Carex Spa Bioreattore destinato ad ospitare cellule animali (da utilizzarsi come organo bioartificiale).

Also Published As

Publication number Publication date
EP1185612B1 (en) 2004-08-25
ES2226850T3 (es) 2005-04-01
AU780160B2 (en) 2005-03-03
JP2003501078A (ja) 2003-01-14
DE60013277D1 (de) 2004-09-30
CA2376039A1 (en) 2000-12-14
WO2000075275A3 (en) 2001-07-19
WO2000075275A2 (en) 2000-12-14
JP4656789B2 (ja) 2011-03-23
AU5180100A (en) 2000-12-28
ATE274571T1 (de) 2004-09-15
ZA200109939B (en) 2003-02-13
DE60013277T2 (de) 2005-08-11
EP1185612A2 (en) 2002-03-13

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130605