HK1044339A1 - 4，5，6和7-吲及二氫吲衍生物，它們的製備和應用 - Google Patents

4，5，6和7-吲及二氫吲衍生物，它們的製備和應用

Info

Publication number
HK1044339A1
HK1044339A1 HK02105927.5A HK02105927A HK1044339A1 HK 1044339 A1 HK1044339 A1 HK 1044339A1 HK 02105927 A HK02105927 A HK 02105927A HK 1044339 A1 HK1044339 A1 HK 1044339A1
Authority
HK
Hong Kong
Prior art keywords
indole
preparation
indoline derivatives
indoline
derivatives
Prior art date
Application number
HK02105927.5A
Other languages
English (en)
Inventor
Knud Moltzen Ejner
Mikkelsen Ivan
Krog-Jensen Christian
Original Assignee
H‧隆德貝克有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/DK1999/000326 external-priority patent/WO1999067237A1/en
Application filed by H‧隆德貝克有限公司 filed Critical H‧隆德貝克有限公司
Publication of HK1044339A1 publication Critical patent/HK1044339A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
HK02105927.5A 1998-06-19 2002-08-13 4，5，6和7-吲及二氫吲衍生物，它們的製備和應用 HK1044339A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK82098 1998-06-19
PCT/DK1999/000326 WO1999067237A1 (en) 1998-06-19 1999-06-14 4,5,6 and 7-indole and indoline derivatives, their preparation and use

Publications (1)

Publication Number Publication Date
HK1044339A1 true HK1044339A1 (zh) 2002-10-18

Family

ID=8097932

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02105927.5A HK1044339A1 (zh) 1998-06-19 2002-08-13 4，5，6和7-吲及二氫吲衍生物，它們的製備和應用

Country Status (16)

Country Link
US (2) US6391882B1 (zh)
KR (1) KR20010071513A (zh)
CN (1) CN1336925A (zh)
AR (1) AR018899A1 (zh)
BR (1) BR9911843A (zh)
CZ (1) CZ20004780A3 (zh)
EA (1) EA004248B1 (zh)
HK (1) HK1044339A1 (zh)
ID (1) ID27976A (zh)
IL (1) IL139962A0 (zh)
IS (1) IS5731A (zh)
PL (1) PL344978A1 (zh)
SK (1) SK19412000A3 (zh)
TR (1) TR200003858T2 (zh)
YU (1) YU78100A (zh)
ZA (1) ZA200007157B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4919565B2 (ja) * 1999-08-23 2012-04-18 アボツト・ヘルスケア・プロダクツ・ベー・ブイ 新規なフェニルピペラジン
DE10219035A1 (de) * 2002-04-29 2003-11-13 Bayer Cropscience Ag Biphenylcarboxamide
US7153858B2 (en) * 2003-01-31 2006-12-26 Epix Delaware, Inc. Arylpiperazinyl compounds
MX2009004898A (es) 2006-11-09 2009-05-19 Hoffmann La Roche Derivados de indol y de benzofurano-2-carboxamida.
WO2010051561A1 (en) * 2008-11-03 2010-05-06 Chemocentryx, Inc. Compounds for the treatment of osteoporosis and cancers
CA2794153C (en) 2010-03-25 2018-01-02 Glaxosmithkline Llc Substituted indoline derivatives as perk inhibitors
CN106243088B (zh) 2015-06-03 2019-01-04 广东东阳光药业有限公司 取代的哌嗪化合物及其使用方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9305641D0 (en) 1993-03-18 1993-05-05 Merck Sharp & Dohme Therapeutic agents
DE4414113A1 (de) 1994-04-22 1995-10-26 Merck Patent Gmbh 3-Indolylpiperidine
IL114026A (en) * 1994-06-08 1999-06-20 Lundbeck & Co As H 4-aryl-1-(indanmethyl dihydrobenzofuranmethyl or dihydrobenzo thiophenemethyl) piperidines tetrahydropyridines or piperazines and pharmaceutical compositions containing them
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives

Also Published As

Publication number Publication date
AR018899A1 (es) 2001-12-12
IL139962A0 (en) 2002-02-10
ZA200007157B (en) 2001-11-22
EA200100056A1 (ru) 2001-06-25
EA004248B1 (ru) 2004-02-26
YU78100A (sh) 2003-04-30
SK19412000A3 (sk) 2001-07-10
TR200003858T2 (tr) 2001-06-21
ID27976A (id) 2001-05-03
US6391882B1 (en) 2002-05-21
CZ20004780A3 (cs) 2001-08-15
BR9911843A (pt) 2001-03-20
US20020128272A1 (en) 2002-09-12
KR20010071513A (ko) 2001-07-28
PL344978A1 (en) 2001-11-19
CN1336925A (zh) 2002-02-20
IS5731A (is) 2000-11-24

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