HK1043319A1 - 17-酮甾類化合物及其衍生物、代謝產物和前體在虐疾的治療以及非洲和美洲錐蟲病的治療中的應用 - Google Patents

17-酮甾類化合物及其衍生物、代謝產物和前體在虐疾的治療以及非洲和美洲錐蟲病的治療中的應用

Info

Publication number
HK1043319A1
HK1043319A1 HK02105184.3A HK02105184A HK1043319A1 HK 1043319 A1 HK1043319 A1 HK 1043319A1 HK 02105184 A HK02105184 A HK 02105184A HK 1043319 A1 HK1043319 A1 HK 1043319A1
Authority
HK
Hong Kong
Prior art keywords
treatment
malaria
african
metabolites
precursors
Prior art date
Application number
HK02105184.3A
Other languages
English (en)
Inventor
克拉倫斯‧納撒尼爾‧阿勒姆
詹姆斯‧馬丁‧弗林克
帕特里克‧T‧普倫德加斯特
Original Assignee
霍利斯--伊登醫葯公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 霍利斯--伊登醫葯公司 filed Critical 霍利斯--伊登醫葯公司
Publication of HK1043319A1 publication Critical patent/HK1043319A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
HK02105184.3A 1998-11-24 2002-07-12 17-酮甾類化合物及其衍生物、代謝產物和前體在虐疾的治療以及非洲和美洲錐蟲病的治療中的應用 HK1043319A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10992398P 1998-11-24 1998-11-24
US12408799P 1999-03-11 1999-03-11
US12605699P 1999-03-23 1999-03-23
PCT/US1999/028079 WO2000032201A2 (en) 1998-11-24 1999-11-24 Use of 17-ketosteroids for the treatment of malaria and trypanosomiasis

Publications (1)

Publication Number Publication Date
HK1043319A1 true HK1043319A1 (zh) 2002-09-13

Family

ID=27380739

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02105184.3A HK1043319A1 (zh) 1998-11-24 2002-07-12 17-酮甾類化合物及其衍生物、代謝產物和前體在虐疾的治療以及非洲和美洲錐蟲病的治療中的應用

Country Status (13)

Country Link
EP (1) EP1135138A2 (zh)
JP (1) JP2002531407A (zh)
KR (2) KR20070004149A (zh)
CN (1) CN1348373A (zh)
AP (1) AP1584A (zh)
AU (2) AU776853B2 (zh)
BR (1) BR9915623A (zh)
CA (1) CA2356539A1 (zh)
HK (1) HK1043319A1 (zh)
IL (1) IL142941A0 (zh)
NZ (1) NZ511720A (zh)
OA (1) OA11715A (zh)
WO (1) WO2000032201A2 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070129282A1 (en) 1998-11-24 2007-06-07 Ahlem Clarence N Pharmaceutical treatments and compositions
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
WO2001003681A2 (en) * 1999-07-08 2001-01-18 Prendergast Patrick T Use of flavones, coumarins and related compounds to treat infections
EP2322182A1 (en) 1999-09-30 2011-05-18 Harbor BioSciences, Inc. Androstenol derivatives as androgen receptor modulator
US20050101581A1 (en) 2002-08-28 2005-05-12 Reading Christopher L. Therapeutic treatment methods 2
US7910755B2 (en) 2004-09-29 2011-03-22 Harbor Biosciences, Inc. Stem cell expansion and uses
US8217025B2 (en) 2006-11-17 2012-07-10 Harbor Therapeutics, Inc. Drug screening and treatment methods
KR100786126B1 (ko) * 2007-08-14 2007-12-18 주식회사 아바코 비접촉 방식에 의한 피절단물의 평탄도를 유지하는스크라이브 헤드 장치 및 그 스크라이브 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL194728C (nl) * 1987-04-16 2003-01-07 Hollis Eden Pharmaceuticals Farmaceutisch preparaat geschikt voor de profylaxe of therapie van een retrovirale infectie of een complicatie of gevolg daarvan.
AU734807B2 (en) * 1996-04-17 2001-06-21 Patrick T. Prendergast Dhea combination therapy
AU5221998A (en) * 1997-04-17 1998-11-13 Patrick T. Prendergast Combination therapy utilising 17-ketosteroids and interleukin inhibitors, or interleukin-10 potionally with interleukin inhibitors

Also Published As

Publication number Publication date
AP2001002182A0 (en) 2001-06-30
JP2002531407A (ja) 2002-09-24
BR9915623A (pt) 2001-08-14
CN1348373A (zh) 2002-05-08
WO2000032201A2 (en) 2000-06-08
EP1135138A2 (en) 2001-09-26
AU776853B2 (en) 2004-09-23
AU2004237812A1 (en) 2005-01-13
CA2356539A1 (en) 2000-06-08
OA11715A (en) 2005-03-14
KR20070004149A (ko) 2007-01-05
WO2000032201A3 (en) 2000-12-21
AU1745300A (en) 2000-06-19
NZ511720A (en) 2002-12-20
AP1584A (en) 2006-03-01
AU2004237812B2 (en) 2007-11-29
IL142941A0 (en) 2002-04-21
KR20010101073A (ko) 2001-11-14

Similar Documents

Publication Publication Date Title
SG85628A1 (en) Compound and its use
HUP0104497A3 (en) Benzamide derivatives, their preparation, medicaments containing them and their use
PL351250A1 (en) Antipicornaviral compounds, their preparation and use
IL137411A0 (en) Novel local anesthetic compounds and uses
HK1043791A1 (en) Imidazole compounds and medicinal use thereof.
GB9817235D0 (en) Compound,composition and use
IL139899A (en) Uracil compounds and use thereof
IL142941A0 (en) Use of 17-ketosteroid compounds and derivatives, metabolites and precursors thereof in the treatment of malaria and the treatment of african and american trypanosomiasis
HK1042426A1 (zh) 17-酮甾類化合物及其衍生物、代謝產物和前體在治療丙型肝炎病毒和其他披膜病毒中的應用
GB9807858D0 (en) Splint
GB9817238D0 (en) Compound,composition and use
HK1044947A1 (en) Benzamide derivatives and drugs containing the same
PL345068A1 (en) Novel compounds derived from α-d-xylose, preparation method and therapeutic use
GB9723859D0 (en) Compound,composition and use
HUP0103569A3 (en) New medicament and process for its preparation
ZA200104825B (en) CVD Titanium-Boron and Chromium-Boron Coating of Diamond.
AU1923500A (en) Use of 17-ketosteroid compounds and derivatives, metabolites and precursors thereof in treatment of toxoplasmosis and in the treatment of cryptosporidiosis
HU9900123D0 (en) 1-isothiazolidinone derivatives of azetidine-2-one, processes for the preparation thereof and use thereof
GB9723858D0 (en) Compound,composition and use
GB9723856D0 (en) Compound,composition and use
GB9723853D0 (en) Compound, composition and use
FI973631A (fi) 1,3-diolipohjaiset eetterit, menetelmä 1,3-diolipohjaisten eetterien valmistamiseksi sekä eetterien käyttö
GB9404200D0 (en) Compound, preparation and use
GB9510167D0 (en) Compound, preparation and use
HUP9901837A3 (en) Frictional and interocking connfection between two elements, especially between two elements of different materials