HK1043309A1 - 影響高密度脂蛋白(hdl)胆固醇和載脂蛋白ai、極低密度脂蛋白(vldl)胆固醇和低密度脂蛋白(ldl)胆固醇的水平的組合物和方法 - Google Patents

影響高密度脂蛋白(hdl)胆固醇和載脂蛋白ai、極低密度脂蛋白(vldl)胆固醇和低密度脂蛋白(ldl)胆固醇的水平的組合物和方法

Info

Publication number
HK1043309A1
HK1043309A1 HK02104818.0A HK02104818A HK1043309A1 HK 1043309 A1 HK1043309 A1 HK 1043309A1 HK 02104818 A HK02104818 A HK 02104818A HK 1043309 A1 HK1043309 A1 HK 1043309A1
Authority
HK
Hong Kong
Prior art keywords
cholesterol
density lipoprotein
low density
vldl
apolipoprotein
Prior art date
Application number
HK02104818.0A
Other languages
English (en)
Inventor
Jaye Michael
j lynch Kevin
V Amin Dilip
Thi Doan Kim-Anh
Marchadier Dawn
Maugeais Cyrille
J Rader Daniel
A Krawiec John
J South Victoria
Original Assignee
Aventis Pharma Inc
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/277,401 external-priority patent/US7008776B1/en
Application filed by Aventis Pharma Inc, Univ Pennsylvania filed Critical Aventis Pharma Inc
Publication of HK1043309A1 publication Critical patent/HK1043309A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK02104818.0A 1999-03-26 2002-06-28 影響高密度脂蛋白(hdl)胆固醇和載脂蛋白ai、極低密度脂蛋白(vldl)胆固醇和低密度脂蛋白(ldl)胆固醇的水平的組合物和方法 HK1043309A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/277,401 US7008776B1 (en) 1996-12-06 1999-03-26 Compositions and methods for effecting the levels of high density lipoprotein (HDL) cholesterol and apolipoprotein AI very low density lipoprotein (VLDL) cholesterol and low density lipoprotein (LDL) cholesterol
PCT/US2000/007870 WO2000057837A2 (en) 1999-03-26 2000-03-24 Compositions and methods for effecting the levels of cholesterol

Publications (1)

Publication Number Publication Date
HK1043309A1 true HK1043309A1 (zh) 2002-09-13

Family

ID=23060703

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02104818.0A HK1043309A1 (zh) 1999-03-26 2002-06-28 影響高密度脂蛋白(hdl)胆固醇和載脂蛋白ai、極低密度脂蛋白(vldl)胆固醇和低密度脂蛋白(ldl)胆固醇的水平的組合物和方法

Country Status (13)

Country Link
EP (1) EP1171078A4 (zh)
JP (1) JP2002540127A (zh)
KR (2) KR20050044812A (zh)
AU (1) AU776684B2 (zh)
BR (1) BR0009333A (zh)
CA (1) CA2363486C (zh)
HK (1) HK1043309A1 (zh)
IL (2) IL145526A0 (zh)
MX (1) MXPA01009727A (zh)
NO (2) NO331779B1 (zh)
NZ (2) NZ514350A (zh)
WO (1) WO2000057837A2 (zh)
ZA (1) ZA200107598B (zh)

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RU2620970C2 (ru) 2008-12-04 2017-05-30 КьюРНА,Инк., Лечение связанных с эритропоэтином (еро) заболеваний путем ингибирования природного антисмыслового транскрипта к еро
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WO2010138806A2 (en) 2009-05-28 2010-12-02 Curna, Inc. Treatment of antiviral gene related diseases by inhibition of natural antisense transcript to an antiviral gene
EP2443238B1 (en) 2009-06-16 2017-03-22 CuRNA, Inc. Treatment of paraoxonase 1 (pon1) related diseases by inhibition of natural antisense transcript to pon1
CA2765700C (en) 2009-06-16 2021-01-05 Opko Curna, Llc Treatment of collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene
JP6073133B2 (ja) 2009-06-24 2017-02-01 クルナ・インコーポレーテッド 腫瘍壊死因子受容体２（ｔｎｆｒ２）に対する天然アンチセンス転写物の抑制によるｔｎｆｒ２関連疾患の治療
KR101807324B1 (ko) 2009-06-26 2017-12-08 큐알엔에이, 인크. 다운 증후군 유전자에 대한 천연 안티센스 전사체의 억제에 의한 다운 증후군 유전자 관련된 질환의 치료
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JP6128848B2 (ja) 2009-08-05 2017-05-17 クルナ・インコーポレーテッド インスリン遺伝子（ｉｎｓ）に対する天然アンチセンス転写物の抑制によるインスリン遺伝子（ｉｎｓ）関連疾患の治療
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EP2467482A4 (en) 2009-08-21 2013-12-11 Curna Inc TREATMENT OF DISEASES RELATED TO "CIP PROTEIN CHIP EXTREME (PROTEIN INTERACTING WITH HSP70)" BY INHIBITION OF CHIP NATURAL ANTISENSE TRANSCRIPT
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WO2011079261A2 (en) 2009-12-23 2011-06-30 Curna, Inc. Treatment of hepatocyte growth factor (hgf) related diseases by inhibition of natural antisense transcript to hgf
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RU2616283C2 (ru) 2009-12-31 2017-04-13 Курна, Инк. Лечение заболеваний, связанных с субстратом рецептора инсулина 2 (irs2), путем ингибирования природного антисмыслового транскрипта к irs2
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RU2611191C2 (ru) 2010-01-11 2017-02-21 Курна, Инк. Лечение заболеваний, связанных со связывающим половые гормоны глобулином (гспг), путем ингибирования природного антисмыслового транскрипта к гспг
JP5981850B2 (ja) 2010-01-25 2016-08-31 カッパーアールエヌエー，インコーポレイテッド ＲＮａｓｅＨ１に対する天然アンチセンス転写物の阻害によるＲＮａｓｅＨ１関連疾患の治療
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TWI644675B (zh) 2010-04-09 2018-12-21 可娜公司 藉由抑制纖維母細胞生長因子２１（ｆｇｆ２１）之天然反義轉錄物以治療ｆｇｆ２１相關疾病
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Also Published As

Publication number Publication date
NO20014657D0 (no) 2001-09-25
CA2363486C (en) 2012-12-18
NO20100214L (no) 2001-11-21
AU3918700A (en) 2000-10-16
WO2000057837A2 (en) 2000-10-05
KR20020029651A (ko) 2002-04-19
ZA200107598B (en) 2003-05-28
BR0009333A (pt) 2002-01-08
NZ531180A (en) 2005-06-24
EP1171078A2 (en) 2002-01-16
NO20014657L (no) 2001-11-21
AU776684B2 (en) 2004-09-16
CA2363486A1 (en) 2000-10-05
NZ514350A (en) 2004-12-24
JP2002540127A (ja) 2002-11-26
NO331779B1 (no) 2012-03-26
MXPA01009727A (es) 2002-07-22
KR100887164B1 (ko) 2009-03-10
KR20050044812A (ko) 2005-05-12
WO2000057837A3 (en) 2001-01-25
IL145526A (en) 2010-11-30
IL145526A0 (en) 2002-06-30
WO2000057837A8 (en) 2001-09-27
EP1171078A4 (en) 2002-11-06
WO2000057837A9 (en) 2001-10-18
NO331784B1 (no) 2012-03-26

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