HK1042692A1 - Diaryl derivatives and their use as medicaments - Google Patents
Diaryl derivatives and their use as medicamentsInfo
- Publication number
- HK1042692A1 HK1042692A1 HK02104536.1A HK02104536A HK1042692A1 HK 1042692 A1 HK1042692 A1 HK 1042692A1 HK 02104536 A HK02104536 A HK 02104536A HK 1042692 A1 HK1042692 A1 HK 1042692A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- medicaments
- diaryl derivatives
- diaryl
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/22—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/67—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfonamide groups, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28010599A | 1999-03-29 | 1999-03-29 | |
PCT/EP2000/002683 WO2000058279A1 (en) | 1999-03-29 | 2000-03-27 | Diaryl derivatives and their use as medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1042692A1 true HK1042692A1 (en) | 2002-08-23 |
Family
ID=23071698
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02104536.1A HK1042692A1 (en) | 1999-03-29 | 2002-06-18 | Diaryl derivatives and their use as medicaments |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1165502A1 (en) |
JP (1) | JP2002540189A (en) |
KR (1) | KR20010105394A (en) |
CN (1) | CN1345309A (en) |
AU (1) | AU4290800A (en) |
BR (1) | BR0009431A (en) |
CA (1) | CA2361016A1 (en) |
CO (1) | CO5160290A1 (en) |
CZ (1) | CZ20013449A3 (en) |
HK (1) | HK1042692A1 (en) |
HU (1) | HUP0200588A2 (en) |
IL (1) | IL144637A0 (en) |
MX (1) | MXPA01009843A (en) |
NO (1) | NO20014702D0 (en) |
NZ (1) | NZ514062A (en) |
PE (1) | PE20001587A1 (en) |
PL (1) | PL349355A1 (en) |
RU (1) | RU2001126579A (en) |
SK (1) | SK13812001A3 (en) |
TR (1) | TR200102225T2 (en) |
WO (1) | WO2000058279A1 (en) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1515548A (en) | 1999-03-01 | 2004-07-28 | �Ʒ� | Oxaminic acid used as thyroid gland receptor ligand and its derivative |
US6790978B2 (en) | 1999-03-29 | 2004-09-14 | Novartis Ag | Thyromimetic organic compounds |
CA2400486C (en) | 2000-02-17 | 2011-01-11 | Bristol-Myers Squibb Company | Aniline-derived ligands for the thyroid receptor |
US6664291B2 (en) | 2000-03-31 | 2003-12-16 | Pfizer, Inc. | Malonamic acids and derivatives thereof as thyroid receptor ligands |
EP1268404B1 (en) * | 2000-03-31 | 2008-01-02 | Pfizer Products Inc. | Malonamic acids and derivatives thereof as thyroid receptor ligands |
AU4884701A (en) * | 2000-05-12 | 2001-11-20 | Kissei Pharmaceutical Co. Ltd. | Malonanilic acid derivatives, medicinal compositions containing the same and usethereof |
US6395784B1 (en) | 2000-06-07 | 2002-05-28 | Bristol-Myers Squibb Company | Benzamide ligands for the thyroid receptor |
DE10038007A1 (en) * | 2000-08-04 | 2002-02-14 | Bayer Ag | New amino and amido diphenyl ethers for drugs |
DE10046029A1 (en) | 2000-09-18 | 2002-03-28 | Bayer Ag | indazoles |
WO2002032408A2 (en) * | 2000-10-20 | 2002-04-25 | Novartis Ag | Combinations of a thyromimetic compound and a statin |
WO2002051805A1 (en) * | 2000-12-27 | 2002-07-04 | Bayer Aktiengesellschaft | Indole derivatives as ligands of thyroid receptors |
US6777442B2 (en) | 2001-03-12 | 2004-08-17 | Bayer Aktiengesellschaft | Diphenyl derivatives |
DE10122443A1 (en) * | 2001-05-09 | 2002-11-14 | Bayer Ag | Amido-diphenyl derivatives |
US6777443B2 (en) | 2001-05-15 | 2004-08-17 | Novartis Ag | Dipeptide derivatives |
DK1262177T3 (en) * | 2001-05-31 | 2006-11-20 | Pfizer Prod Inc | Medical use of thyromimetic compounds for the treatment of hair loss and compositions |
DE10131462A1 (en) * | 2001-06-29 | 2003-01-09 | Bayer Ag | Phenol derivatives |
ES2253495T3 (en) | 2001-09-26 | 2006-06-01 | Pfizer Products Inc. | INDO CARBOXILIC ACIDS AS LIGHTING OF THYROID RECEPTORS. |
US6818766B2 (en) | 2002-10-02 | 2004-11-16 | Synthon Bv | Process for making bicalutamide and intermediates thereof |
CA2546601A1 (en) | 2003-11-19 | 2005-06-09 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing thyromimetics |
US20080255240A1 (en) * | 2004-05-05 | 2008-10-16 | Novo Nordisk A/S | Sulfonamide Derivatives |
MX2007001215A (en) | 2004-08-06 | 2007-04-17 | Otsuka Pharma Co Ltd | Aromatic compounds. |
EP1898926A2 (en) | 2005-05-26 | 2008-03-19 | Metabasis Therapeutics, Inc. | Thyromimetics for the treatment of fatty liver diseases |
US8236826B2 (en) | 2005-12-05 | 2012-08-07 | Otsuka Pharmaceutical Co., Ltd. | Diarylether derivatives as antitumor agents |
UA95978C2 (en) | 2006-10-02 | 2011-09-26 | Оцука Фармас'Ютікел Ко., Лтд. | Stat3/5 activation inhibitor |
WO2009133834A1 (en) * | 2008-04-28 | 2009-11-05 | 塩野義製薬株式会社 | Keto-amide derivative having inhibitory activity on endothelial lipase |
TW201512171A (en) | 2013-04-19 | 2015-04-01 | Pfizer Ltd | Chemical compounds |
CN104193699B (en) * | 2014-08-14 | 2016-05-25 | 嘉兴特科罗生物科技有限公司 | A kind of micromolecular compound and synthetic method and application |
CA3044059A1 (en) | 2016-11-21 | 2018-05-24 | Viking Therapeutics, Inc. | Method of treating glycogen storage disease |
EA201992703A1 (en) | 2017-06-05 | 2020-04-15 | Вайкинг Терапьютикс, Инк. | COMPOSITIONS FOR TREATING FIBROSIS |
CA3094167A1 (en) | 2018-03-22 | 2019-09-26 | Viking Therapeutics, Inc. | Crystalline forms and methods of producing crystalline forms of a compound |
CN112300133A (en) * | 2019-07-31 | 2021-02-02 | 深圳微芯生物科技股份有限公司 | Heterocyclic compound and application thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69314718T2 (en) * | 1992-07-21 | 1998-02-26 | Ciba Geigy Ag | Oxamic acid derivatives as hypocholesteremic agents |
-
2000
- 2000-03-22 CO CO00020338A patent/CO5160290A1/en unknown
- 2000-03-27 CA CA002361016A patent/CA2361016A1/en not_active Abandoned
- 2000-03-27 SK SK1381-2001A patent/SK13812001A3/en unknown
- 2000-03-27 CZ CZ20013449A patent/CZ20013449A3/en unknown
- 2000-03-27 JP JP2000607982A patent/JP2002540189A/en active Pending
- 2000-03-27 PE PE2000000260A patent/PE20001587A1/en not_active Application Discontinuation
- 2000-03-27 TR TR2001/02225T patent/TR200102225T2/en unknown
- 2000-03-27 RU RU2001126579/04A patent/RU2001126579A/en unknown
- 2000-03-27 CN CN00805693A patent/CN1345309A/en active Pending
- 2000-03-27 NZ NZ514062A patent/NZ514062A/en not_active Application Discontinuation
- 2000-03-27 IL IL14463700A patent/IL144637A0/en unknown
- 2000-03-27 BR BR0009431-5A patent/BR0009431A/en not_active Application Discontinuation
- 2000-03-27 HU HU0200588A patent/HUP0200588A2/en unknown
- 2000-03-27 PL PL00349355A patent/PL349355A1/en not_active Application Discontinuation
- 2000-03-27 KR KR1020017012250A patent/KR20010105394A/en not_active Application Discontinuation
- 2000-03-27 EP EP00922557A patent/EP1165502A1/en not_active Withdrawn
- 2000-03-27 MX MXPA01009843A patent/MXPA01009843A/en unknown
- 2000-03-27 AU AU42908/00A patent/AU4290800A/en not_active Abandoned
- 2000-03-27 WO PCT/EP2000/002683 patent/WO2000058279A1/en not_active Application Discontinuation
-
2001
- 2001-09-27 NO NO20014702A patent/NO20014702D0/en unknown
-
2002
- 2002-06-18 HK HK02104536.1A patent/HK1042692A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO20014702L (en) | 2001-09-27 |
IL144637A0 (en) | 2002-05-23 |
KR20010105394A (en) | 2001-11-28 |
PE20001587A1 (en) | 2001-01-31 |
CZ20013449A3 (en) | 2001-12-12 |
SK13812001A3 (en) | 2002-04-04 |
HUP0200588A2 (en) | 2002-07-29 |
NO20014702D0 (en) | 2001-09-27 |
AU4290800A (en) | 2000-10-16 |
CO5160290A1 (en) | 2002-05-30 |
CN1345309A (en) | 2002-04-17 |
EP1165502A1 (en) | 2002-01-02 |
WO2000058279A1 (en) | 2000-10-05 |
TR200102225T2 (en) | 2002-01-21 |
CA2361016A1 (en) | 2000-10-05 |
MXPA01009843A (en) | 2002-05-06 |
PL349355A1 (en) | 2002-07-15 |
JP2002540189A (en) | 2002-11-26 |
RU2001126579A (en) | 2004-02-27 |
NZ514062A (en) | 2001-09-28 |
BR0009431A (en) | 2002-01-08 |
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