HK1041823A1 - 含有乙酰水楊酸和氯吡格雷硫酸氫鹽的單位劑型形藥物組合物 - Google Patents

含有乙酰水楊酸和氯吡格雷硫酸氫鹽的單位劑型形藥物組合物

Info

Publication number
HK1041823A1
HK1041823A1 HK02103639.9A HK02103639A HK1041823A1 HK 1041823 A1 HK1041823 A1 HK 1041823A1 HK 02103639 A HK02103639 A HK 02103639A HK 1041823 A1 HK1041823 A1 HK 1041823A1
Authority
HK
Hong Kong
Prior art keywords
acetylsalcylic
acid
pharmaceutical composition
unit form
form containing
Prior art date
Application number
HK02103639.9A
Other languages
English (en)
Chinese (zh)
Inventor
Abramovici Bernard
Lheritier Jean
Original Assignee
聖諾菲-合成實驗室公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 聖諾菲-合成實驗室公司 filed Critical 聖諾菲-合成實驗室公司
Publication of HK1041823A1 publication Critical patent/HK1041823A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • A61K31/612Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Surgery (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HK02103639.9A 1999-04-30 2002-05-14 含有乙酰水楊酸和氯吡格雷硫酸氫鹽的單位劑型形藥物組合物 HK1041823A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9905497A FR2792836B3 (fr) 1999-04-30 1999-04-30 Composition pharmaceutique sous forme unitaire contenant de l'aspirine et de l'hydrogenosulfate de clopidogrel
PCT/FR2000/001086 WO2000066130A1 (fr) 1999-04-30 2000-04-25 Composition pharmaceutique sous forme unitaire contenant de l'acide acetylsalicylique et de l'hydrogenosulfate de clopidogrel

Publications (1)

Publication Number Publication Date
HK1041823A1 true HK1041823A1 (zh) 2002-07-26

Family

ID=9545071

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02103639.9A HK1041823A1 (zh) 1999-04-30 2002-05-14 含有乙酰水楊酸和氯吡格雷硫酸氫鹽的單位劑型形藥物組合物

Country Status (24)

Country Link
EP (1) EP1178809A1 (fr)
JP (1) JP2002543137A (fr)
KR (1) KR20020005735A (fr)
CN (1) CN1359294A (fr)
AR (1) AR023789A1 (fr)
AU (1) AU4303600A (fr)
BR (1) BR0010194A (fr)
CA (1) CA2371231A1 (fr)
CZ (1) CZ20013887A3 (fr)
EA (1) EA200100959A1 (fr)
EE (1) EE200100559A (fr)
FR (1) FR2792836B3 (fr)
HK (1) HK1041823A1 (fr)
HU (1) HUP0202329A2 (fr)
IL (1) IL145648A0 (fr)
IS (1) IS6084A (fr)
MX (1) MXPA01011071A (fr)
NO (1) NO20015295L (fr)
NZ (1) NZ514248A (fr)
PL (1) PL351923A1 (fr)
SK (1) SK15542001A3 (fr)
TR (1) TR200103039T2 (fr)
UY (1) UY26131A1 (fr)
WO (1) WO2000066130A1 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60135780D1 (de) 2000-12-25 2008-10-23 Daiichi Sankyo Co Ltd Aspirin enthaltende medizinische zusammensetzungen
US6767913B2 (en) 2001-12-18 2004-07-27 Teva Pharmaceutical Industries Ltd. Crystal forms iii, iv, v, and novel amorphous form of clopidogrel hydrogensulfate, processes for their preparation, processes for the preparation of form i, compositions containing the new forms and methods of administering the new forms
US7074928B2 (en) 2002-01-11 2006-07-11 Teva Pharmaceutical Industries, Ltd. Polymorphs of clopidogrel hydrogensulfate
US6800759B2 (en) 2002-08-02 2004-10-05 Teva Pharmaceutical Industries Ltd. Racemization and enantiomer separation of clopidogrel
IL166593A0 (en) 2002-08-02 2006-01-15 Racemization and enantiomer separation of clopidogrel
JP4917255B2 (ja) * 2003-10-16 2012-04-18 第一三共ヘルスケア株式会社 サリチル酸類含有経口組成物
WO2005070464A2 (fr) * 2004-01-21 2005-08-04 Biofarma Ilac Sanayi Ve Ticaret A.S. Formulation de comprimes de bisulfate de clopidogrel
JP2008543843A (ja) * 2005-06-13 2008-12-04 エラン ファーマ インターナショナル リミテッド ナノ粒子クロピドグレル及びアスピリンの配合製剤
KR20070009851A (ko) * 2005-07-14 2007-01-19 씨제이 주식회사 클로피도그렐 황산수소염 함유 약학 조성물
KR100736024B1 (ko) * 2005-09-21 2007-07-06 주식회사종근당 신규한 클로피도그렐 우선성 광학이성체의 이온교환수지착체와 그 제조방법
KR20070044323A (ko) * 2005-10-24 2007-04-27 에스케이케미칼주식회사 보관안정성이 개선된 클로피도그렐 황산수소염 함유 경구용제제
US20100145053A1 (en) * 2006-04-05 2010-06-10 Cadila Healthcare Limited Modified release clopidogrel formulation
EP1900358A1 (fr) * 2006-09-16 2008-03-19 Cimex Pharma AG Formulations pharmaceutiques contenant du clopidogrel
HUP0600839A3 (en) * 2006-11-14 2008-09-29 Egis Gyogyszergyar Nyrt Solid pharmaceutical composition containing polymorph i of clopidogrel hydrogensulfate and process for the preparation thereof
EP2255797A4 (fr) * 2008-02-22 2011-09-07 Hanall Biopharma Co Ltd Préparation composite
CN101695496A (zh) * 2009-10-15 2010-04-21 苏春华 一种含有三氟柳和氯吡格雷的药物组合物
JP2013032289A (ja) * 2009-10-28 2013-02-14 Daiichi Sankyo Co Ltd ワックス安定製剤
RU2484820C2 (ru) * 2011-02-24 2013-06-20 Общество с ограниченной ответственностью "Озон" Комбинированное лекарственное средство, являющееся ингибитором агрегации тромбоцитов
KR101675501B1 (ko) 2011-11-02 2016-11-14 한국유나이티드제약 주식회사 클로피도그렐 및 아스피린의 복합제제
CN102406938A (zh) * 2011-11-29 2012-04-11 北京阜康仁生物制药科技有限公司 一种抗血栓的药物组合物
JP6004524B2 (ja) * 2012-07-11 2016-10-12 大原薬品工業株式会社 クロピドグレル硫酸塩含有錠剤の製造方法
JP5905165B2 (ja) * 2013-08-02 2016-04-20 サノフイ アセチルサリチル酸およびクロピドグレルを含む医薬錠剤
CN104434932B (zh) * 2014-12-18 2017-05-24 成都苑东生物制药股份有限公司 一种硫酸氢氯吡格雷阿司匹林片药物组合物及其制备方法
WO2017037741A1 (fr) * 2015-09-02 2017-03-09 Sun Pharmaceutical Industries Ltd Forme posologique solide et compacte à base d'aspirine et de clopidogrel
CN115737578A (zh) * 2022-11-23 2023-03-07 石家庄四药有限公司 一种硫酸氢氯吡格雷阿司匹林复方片及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623810B2 (fr) 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
US5576328A (en) * 1994-01-31 1996-11-19 Elf Sanofi Method for the secondary prevention of ischemic events
FR2744918B1 (fr) 1996-02-19 1998-05-07 Sanofi Sa Nouvelles associations de principes actifs contenant un derive de thieno(3,2-c)pyridine et un antithrombotique
FR2779726B1 (fr) 1998-06-15 2001-05-18 Sanofi Sa Forme polymorphe de l'hydrogenosulfate de clopidogrel

Also Published As

Publication number Publication date
EP1178809A1 (fr) 2002-02-13
TR200103039T2 (tr) 2002-01-21
CA2371231A1 (fr) 2000-11-09
EA200100959A1 (ru) 2002-06-27
SK15542001A3 (sk) 2002-02-05
NO20015295L (no) 2001-12-21
MXPA01011071A (es) 2002-07-22
AR023789A1 (es) 2002-09-04
NZ514248A (en) 2003-06-30
UY26131A1 (es) 2000-12-29
EE200100559A (et) 2003-02-17
AU4303600A (en) 2000-11-17
IS6084A (is) 2001-09-25
FR2792836B3 (fr) 2001-07-27
BR0010194A (pt) 2002-02-13
NO20015295D0 (no) 2001-10-29
HUP0202329A2 (en) 2002-10-28
PL351923A1 (en) 2003-06-30
CN1359294A (zh) 2002-07-17
WO2000066130A1 (fr) 2000-11-09
CZ20013887A3 (cs) 2002-02-13
FR2792836A1 (fr) 2000-11-03
IL145648A0 (en) 2002-06-30
JP2002543137A (ja) 2002-12-17
KR20020005735A (ko) 2002-01-17

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