HK1038913A1 - Arylsulfonanilide ureas - Google Patents

Arylsulfonanilide ureas

Info

Publication number
HK1038913A1
HK1038913A1 HK02100388A HK02100388A HK1038913A1 HK 1038913 A1 HK1038913 A1 HK 1038913A1 HK 02100388 A HK02100388 A HK 02100388A HK 02100388 A HK02100388 A HK 02100388A HK 1038913 A1 HK1038913 A1 HK 1038913A1
Authority
HK
Hong Kong
Prior art keywords
agents
compositions
arylsulfonanilide
ureas
hypercholesterolemia
Prior art date
Application number
HK02100388A
Other languages
English (en)
Inventor
Jonathan B Houze
Original Assignee
Tularik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tularik Inc filed Critical Tularik Inc
Publication of HK1038913A1 publication Critical patent/HK1038913A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
HK02100388A 1998-09-23 2002-01-17 Arylsulfonanilide ureas HK1038913A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10088898P 1998-09-23 1998-09-23
PCT/US1999/022013 WO2000017159A1 (en) 1998-09-23 1999-09-21 Arylsulfonanilide ureas

Publications (1)

Publication Number Publication Date
HK1038913A1 true HK1038913A1 (en) 2002-04-04

Family

ID=22282047

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02100388A HK1038913A1 (en) 1998-09-23 2002-01-17 Arylsulfonanilide ureas

Country Status (24)

Country Link
US (3) US6214880B1 (xx)
EP (1) EP1115701B1 (xx)
JP (1) JP3926983B2 (xx)
KR (1) KR100642184B1 (xx)
CN (1) CN100335461C (xx)
AT (1) ATE240940T1 (xx)
AU (1) AU747663B2 (xx)
BR (1) BR9913903A (xx)
CA (1) CA2343204C (xx)
CZ (1) CZ2001934A3 (xx)
DE (1) DE69908156T2 (xx)
DK (1) DK1115701T3 (xx)
EA (1) EA003924B1 (xx)
ES (1) ES2194547T3 (xx)
HK (1) HK1038913A1 (xx)
HU (1) HUP0103884A3 (xx)
IL (2) IL142066A0 (xx)
NO (1) NO20011453L (xx)
NZ (1) NZ510435A (xx)
PL (1) PL198394B1 (xx)
PT (1) PT1115701E (xx)
SK (1) SK284757B6 (xx)
WO (1) WO2000017159A1 (xx)
ZA (1) ZA200102033B (xx)

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PL198394B1 (pl) * 1998-09-23 2008-06-30 Amgen Inc Związki pochodne arylosulfonoanilidomocznika, ich zastosowanie oraz zawierające je kompozycje farmaceutyczne
US6316503B1 (en) * 1999-03-15 2001-11-13 Tularik Inc. LXR modulators
US6355628B1 (en) * 1999-07-29 2002-03-12 Tularik Inc. Combination therapy using pentafluorobenzenesulfonamides
US6664259B2 (en) 2000-03-16 2003-12-16 Smithkline Beecham Corporation Il-8 receptor antagonists
CO5280089A1 (es) * 2000-03-16 2003-05-30 Smithkline Beecham Corp Antagonistas del receptor il-8
UY26627A1 (es) * 2000-03-24 2001-09-28 Smithkline Beecham Corp Antagonistas de receptores de il-8
WO2002020463A2 (en) * 2000-09-05 2002-03-14 Tularik Inc. Fxr modulators
US20050250854A1 (en) * 2000-11-03 2005-11-10 Amgen Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
AU2002234165A1 (en) 2000-11-03 2002-05-27 Tularik, Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
IL157540A0 (en) 2001-02-28 2004-03-28 Univ Temple N-(aryl)-2-arylethenesulphonamides and therapeutic uses thereof
AUPR738301A0 (en) * 2001-08-30 2001-09-20 Starpharma Limited Chemotherapeutic agents
WO2003063796A2 (en) * 2002-01-30 2003-08-07 Tularik Inc. Heterocyclic arylsulfonamidobenzylic compounds
ATE411279T1 (de) * 2002-01-30 2008-10-15 Amgen Inc Arylsulfonamidobenzylverbindungen
IL163608A0 (en) 2002-02-28 2005-12-18 Univ Temple Amino-substituted sulfonanilides and derivatives thereof for treating proliferative disorders
AR041834A1 (es) * 2002-10-29 2005-06-01 Smithkline Beecham Corp Compuesto de difenilurea sustituido con sulfonamida, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion
WO2005016277A2 (en) * 2003-08-12 2005-02-24 Amgen Inc. Arylsulfonamidobenzylic compounds
US20050124664A1 (en) * 2003-10-30 2005-06-09 Eric Sartori Urea thiadiazole inhibitors of plasminogen activator inhibior-1
US20050154455A1 (en) * 2003-12-18 2005-07-14 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20050261762A1 (en) * 2004-05-21 2005-11-24 Medtronic Vascular, Inc. Medical devices to prevent or inhibit restenosis
US20060062822A1 (en) * 2004-09-21 2006-03-23 Medtronic Vascular, Inc. Medical devices to treat or inhibit restenosis
US20070027530A1 (en) * 2005-07-26 2007-02-01 Medtronic Vascular, Inc. Intraluminal device, catheter assembly, and method of use thereof
FI20055498A0 (fi) * 2005-09-16 2005-09-16 Biotie Therapies Corp Sulfonamidijohdannaisia
US20070067020A1 (en) * 2005-09-22 2007-03-22 Medtronic Vasular, Inc. Intraluminal stent, delivery system, and a method of treating a vascular condition
CN101495113A (zh) * 2006-04-21 2009-07-29 史密丝克莱恩比彻姆公司 Il-8受体拮抗剂
BRPI0710232B8 (pt) * 2006-04-21 2021-05-25 Glaxosmithkline Llc composto antagonista do receptor de il-8, composição farmacêutica que compreende o dito composto e uso do mesmo para o tratamento de uma doença mediada por quimiocina
MX2008014953A (es) * 2006-05-26 2009-03-05 Bayer Healthcare Llc Combinaciones de medicamentos con diarilureas sustituidas para el tratamiento de cancer.
CL2007001829A1 (es) * 2006-06-23 2008-01-25 Smithkline Beecham Corp P-toluensulfonato de n-[4-cloro-2-hidroxi-3-(piperazina-1-sulfonil)fenil]-n-(2-cloro-3-fluorofenil)urea;procedimiento de preparacion;composicion farmaceutica;combinacion farmaceutica;y uso en el tratamiento de una enfermedad mediada por la quiimioquina il-8, tales como asma y epoc.
US8252841B2 (en) * 2007-10-19 2012-08-28 The Board Of Regents Of The University Of Texas System Methods of inhibiting bacterial virulence and compounds relating thereto
WO2010123591A2 (en) * 2009-01-09 2010-10-28 The Uab Research Foundation Small molecule inhibitors of nads, namnat, and nmnat
US9444712B2 (en) 2012-11-21 2016-09-13 Cisco Technology, Inc. Bandwidth on-demand services in multiple layer networks
WO2014080615A1 (ja) * 2012-11-21 2014-05-30 日本曹達株式会社 非フェノール系化合物を用いた記録材料
EP3438091A4 (en) * 2016-03-30 2019-11-27 Ajinomoto Co., Inc. CONNECTION WITH INCREASING ACTIVITY FOR ACTION OF GLUCAGON LIKE PEPTIDE-1 RECEPTOR

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PT939627E (pt) * 1996-07-19 2004-02-27 Tularik Inc Pentafluorobenzenossulfonamidas e analogos
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PL198394B1 (pl) * 1998-09-23 2008-06-30 Amgen Inc Związki pochodne arylosulfonoanilidomocznika, ich zastosowanie oraz zawierające je kompozycje farmaceutyczne
US6355628B1 (en) * 1999-07-29 2002-03-12 Tularik Inc. Combination therapy using pentafluorobenzenesulfonamides

Also Published As

Publication number Publication date
EA200100376A1 (ru) 2001-08-27
WO2000017159A1 (en) 2000-03-30
CZ2001934A3 (cs) 2001-08-15
SK4002001A3 (en) 2001-09-11
CN1319088A (zh) 2001-10-24
US6214880B1 (en) 2001-04-10
EA003924B1 (ru) 2003-10-30
DE69908156D1 (de) 2003-06-26
HUP0103884A2 (hu) 2002-05-29
SK284757B6 (sk) 2005-11-03
KR100642184B1 (ko) 2006-11-10
AU6058099A (en) 2000-04-10
EP1115701A1 (en) 2001-07-18
KR20010079892A (ko) 2001-08-22
US20010027211A1 (en) 2001-10-04
DK1115701T3 (da) 2003-06-23
JP3926983B2 (ja) 2007-06-06
NO20011453L (no) 2001-05-23
US20030207864A1 (en) 2003-11-06
ZA200102033B (en) 2001-09-12
IL142066A (en) 2006-07-05
CA2343204A1 (en) 2000-03-30
AU747663B2 (en) 2002-05-16
DE69908156T2 (de) 2003-12-24
ATE240940T1 (de) 2003-06-15
PT1115701E (pt) 2003-09-30
PL346797A1 (en) 2002-02-25
JP2002526472A (ja) 2002-08-20
US7060718B2 (en) 2006-06-13
NZ510435A (en) 2003-04-29
BR9913903A (pt) 2001-07-03
PL198394B1 (pl) 2008-06-30
EP1115701B1 (en) 2003-05-21
NO20011453D0 (no) 2001-03-22
ES2194547T3 (es) 2003-11-16
IL142066A0 (en) 2002-03-10
CA2343204C (en) 2008-04-29
CN100335461C (zh) 2007-09-05
US6583165B2 (en) 2003-06-24
HUP0103884A3 (en) 2002-11-28

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090921