HK1024872A1 - Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of dementia - Google Patents

Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of dementia

Info

Publication number
HK1024872A1
HK1024872A1 HK00104146A HK00104146A HK1024872A1 HK 1024872 A1 HK1024872 A1 HK 1024872A1 HK 00104146 A HK00104146 A HK 00104146A HK 00104146 A HK00104146 A HK 00104146A HK 1024872 A1 HK1024872 A1 HK 1024872A1
Authority
HK
Hong Kong
Prior art keywords
cyclooxygenase
inhibitors
dementia
prevention
treatment
Prior art date
Application number
HK00104146A
Other languages
English (en)
Inventor
Philip Needleman
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of HK1024872A1 publication Critical patent/HK1024872A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK00104146A 1997-04-03 2000-07-06 Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of dementia HK1024872A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4391697P 1997-04-03 1997-04-03
PCT/US1998/006143 WO1998043648A1 (fr) 1997-04-03 1998-03-30 Procede se rapportant a l'utilisation d'inhibiteurs de la cyclo-oxygenase-2 pour le traitement et la prevention de la demence

Publications (1)

Publication Number Publication Date
HK1024872A1 true HK1024872A1 (en) 2000-10-27

Family

ID=21929578

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00104146A HK1024872A1 (en) 1997-04-03 2000-07-06 Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of dementia

Country Status (13)

Country Link
EP (1) EP0971714B1 (fr)
JP (1) JP2002514208A (fr)
AT (1) ATE225660T1 (fr)
AU (1) AU725697B2 (fr)
BR (1) BR9807920A (fr)
CA (1) CA2285434A1 (fr)
DE (1) DE69808607T2 (fr)
DK (1) DK0971714T3 (fr)
ES (1) ES2185154T3 (fr)
HK (1) HK1024872A1 (fr)
PT (1) PT971714E (fr)
WO (1) WO1998043648A1 (fr)
ZA (1) ZA982808B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6727238B2 (en) 1998-06-11 2004-04-27 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
US6294558B1 (en) 1999-05-31 2001-09-25 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9420616D0 (en) * 1994-10-12 1994-11-30 Merck Sharp & Dohme Method, compositions and use
NZ336428A (en) * 1993-11-30 2005-02-25 G use of substituted pyrazolyl benzosulphonamides to treat inflammation
US5486534A (en) * 1994-07-21 1996-01-23 G. D. Searle & Co. 3,4-substituted pyrazoles for the treatment of inflammation
US5696143A (en) * 1994-09-20 1997-12-09 Talley; John J. Benz G! indazolyl derivatives for the treatment of inflammation
US5547975A (en) * 1994-09-20 1996-08-20 Talley; John J. Benzopyranopyrazolyl derivatives for the treatment of inflammation
US5643933A (en) * 1995-06-02 1997-07-01 G. D. Searle & Co. Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
WO1996038418A1 (fr) * 1995-06-02 1996-12-05 G.D. Searle & Co. Derives heterocyclo-substitues d'acide hydroxamique utilises comme inhibiteurs de la cyclo-oxygenase-2 et de la 5-lipoxygenase
EP0833622B8 (fr) * 1995-06-12 2005-10-12 G.D. Searle & Co. Compositions comprenant un inhibiteur de cyclooxygenase-2 et un inhibiteur de 5-lipoxygenase
US5700816A (en) * 1995-06-12 1997-12-23 Isakson; Peter C. Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitor and a leukotriene A4 hydrolase inhibitor
CA2224563A1 (fr) * 1995-06-12 1996-12-27 G.D. Searle & Co. Traitement d'inflammations par une combinaison d'un inhibiteur de la cyclooxygenase-2 et d'un antagoniste du recepteur de leukotriene b4
RO121338B1 (ro) * 1996-04-12 2007-03-30 G.D. Searle & Co. Derivaţi de benzensulfonamidă, procedeu de preparare a acestora, compoziţie farmaceutică şi utilizarea ca inhibitori de cox-2

Also Published As

Publication number Publication date
DE69808607T2 (de) 2003-06-26
DK0971714T3 (da) 2002-11-04
DE69808607D1 (de) 2002-11-14
WO1998043648A1 (fr) 1998-10-08
AU6590498A (en) 1998-10-22
EP0971714A1 (fr) 2000-01-19
JP2002514208A (ja) 2002-05-14
BR9807920A (pt) 2000-02-22
ZA982808B (en) 1999-04-06
PT971714E (pt) 2002-12-31
EP0971714B1 (fr) 2002-10-09
ES2185154T3 (es) 2003-04-16
ATE225660T1 (de) 2002-10-15
AU725697B2 (en) 2000-10-19
CA2285434A1 (fr) 1998-10-08

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20070330