ZA982808B - Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of dementia - Google Patents

Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of dementia

Info

Publication number
ZA982808B
ZA982808B ZA982808A ZA982808A ZA982808B ZA 982808 B ZA982808 B ZA 982808B ZA 982808 A ZA982808 A ZA 982808A ZA 982808 A ZA982808 A ZA 982808A ZA 982808 B ZA982808 B ZA 982808B
Authority
ZA
South Africa
Prior art keywords
cyclooxygenase
inhibitors
dementia
prevention
treatment
Prior art date
Application number
ZA982808A
Other languages
English (en)
Inventor
Phillip Needleman
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of ZA982808B publication Critical patent/ZA982808B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA982808A 1997-04-03 1998-04-02 Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of dementia ZA982808B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4391697P 1997-04-03 1997-04-03

Publications (1)

Publication Number Publication Date
ZA982808B true ZA982808B (en) 1999-04-06

Family

ID=21929578

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA982808A ZA982808B (en) 1997-04-03 1998-04-02 Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of dementia

Country Status (13)

Country Link
EP (1) EP0971714B1 (xx)
JP (1) JP2002514208A (xx)
AT (1) ATE225660T1 (xx)
AU (1) AU725697B2 (xx)
BR (1) BR9807920A (xx)
CA (1) CA2285434A1 (xx)
DE (1) DE69808607T2 (xx)
DK (1) DK0971714T3 (xx)
ES (1) ES2185154T3 (xx)
HK (1) HK1024872A1 (xx)
PT (1) PT971714E (xx)
WO (1) WO1998043648A1 (xx)
ZA (1) ZA982808B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6727238B2 (en) 1998-06-11 2004-04-27 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
US6294558B1 (en) 1999-05-31 2001-09-25 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9420616D0 (en) * 1994-10-12 1994-11-30 Merck Sharp & Dohme Method, compositions and use
NZ336428A (en) * 1993-11-30 2005-02-25 G use of substituted pyrazolyl benzosulphonamides to treat inflammation
US5486534A (en) * 1994-07-21 1996-01-23 G. D. Searle & Co. 3,4-substituted pyrazoles for the treatment of inflammation
US5696143A (en) * 1994-09-20 1997-12-09 Talley; John J. Benz G! indazolyl derivatives for the treatment of inflammation
US5547975A (en) * 1994-09-20 1996-08-20 Talley; John J. Benzopyranopyrazolyl derivatives for the treatment of inflammation
US5643933A (en) * 1995-06-02 1997-07-01 G. D. Searle & Co. Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
WO1996038418A1 (en) * 1995-06-02 1996-12-05 G.D. Searle & Co. Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
EP0833622B8 (en) * 1995-06-12 2005-10-12 G.D. Searle & Co. Compositions comprising a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor
US5700816A (en) * 1995-06-12 1997-12-23 Isakson; Peter C. Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitor and a leukotriene A4 hydrolase inhibitor
CA2224563A1 (en) * 1995-06-12 1996-12-27 G.D. Searle & Co. Combination of a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist for the treatment of inflammations
RO121338B1 (ro) * 1996-04-12 2007-03-30 G.D. Searle & Co. Derivaţi de benzensulfonamidă, procedeu de preparare a acestora, compoziţie farmaceutică şi utilizarea ca inhibitori de cox-2

Also Published As

Publication number Publication date
DE69808607T2 (de) 2003-06-26
DK0971714T3 (da) 2002-11-04
DE69808607D1 (de) 2002-11-14
WO1998043648A1 (en) 1998-10-08
AU6590498A (en) 1998-10-22
EP0971714A1 (en) 2000-01-19
HK1024872A1 (en) 2000-10-27
JP2002514208A (ja) 2002-05-14
BR9807920A (pt) 2000-02-22
PT971714E (pt) 2002-12-31
EP0971714B1 (en) 2002-10-09
ES2185154T3 (es) 2003-04-16
ATE225660T1 (de) 2002-10-15
AU725697B2 (en) 2000-10-19
CA2285434A1 (en) 1998-10-08

Similar Documents

Publication Publication Date Title
CA2267186A1 (en) Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia
WO2001066564A3 (en) Gamma-secretase inhibitors
WO1999005096A3 (en) Urokinase inhibitors
UA35589C2 (uk) ІНГІБІТОРИ ТЕСТОСТЕРОН 5-<font face="Symbol">a</font>-РЕДУКТАЗИ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ТА СПОСІБ ІНГІБУВАННЯ АКТИВНОСТІ ТЕСТОСТЕРОН 5-<font face="Symbol">a</font>-РЕДУКТАЗИ
AP9901478A0 (en) Compounds for the treatment of ischemia.
MX9804623A (es) Precursores inactivos de farmacos inhibidores de trombina.
AU5242000A (en) Nematicidal trifluorobutenes
WO2001005392A3 (en) Method for treating chronic pain using mek inhibitors
CA2257010A1 (en) Methods and compositions for the treatment and prevention of tumors, tumor-related disorders and cachexia
EP0528858A4 (en) Inhibitors of dipeptidyl-aminopeptidase type iv
CA2282654A1 (en) Use of cholinesterase inhibitors to treat attention deficit hyperactivity disorder
ATE225351T1 (de) Thienopyridin und thienopyrimidinderivate und ihre verwendung als entzündungshemmende mittel
MX9606744A (es) Acidos hidroxamicos sustituidos por sulfonamido arilico como inhibidores de metaloproteinasa de matriz.
MX9700557A (es) Dihidrobenzofuranos.
WO1994004541A3 (en) Protein kinase inhibitors and related compounds combined with taxol
BG101110A (en) Substituted pyrimidine compounds and their application
CA2210258A1 (en) Substituted oxazolidine calpain and/or cathepsin b inhibitors
WO1998036730A3 (de) Zubereitungen für die behandlung von rosacea
NZ332096A (en) Alpha-hydroxylic acid derivatives their production and use in treating conditions requiring endothelin inhibition
CA2270469A1 (en) Method of using cyclooxygenase-2 inhibitors as anti-angiogenic agents
WO2002005642A3 (en) Synergistic biocidal compositions
CA2200126A1 (en) Treatment and prophylaxis of pancreatitis
AU9066498A (en) Substituted 6-alkylphenanthridines
MX9700624A (es) Azolidinonas de imidazopiridina.
HK1024872A1 (en) Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of dementia