HK1020042A1 - New vitamin derivatives with carbo- or heterocyclic substituents at c-25, a process for their production, intermediate products and their use for producing medicaments. - Google Patents
New vitamin derivatives with carbo- or heterocyclic substituents at c-25, a process for their production, intermediate products and their use for producing medicaments.Info
- Publication number
- HK1020042A1 HK1020042A1 HK99105222A HK99105222A HK1020042A1 HK 1020042 A1 HK1020042 A1 HK 1020042A1 HK 99105222 A HK99105222 A HK 99105222A HK 99105222 A HK99105222 A HK 99105222A HK 1020042 A1 HK1020042 A1 HK 1020042A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- sub
- diseases
- hypercalcemias
- carbo
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
- C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
- C07C35/32—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system being a (4.3.0) system, e.g. indenols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Electroluminescent Light Sources (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19619036A DE19619036A1 (de) | 1996-04-30 | 1996-04-30 | Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
PCT/EP1997/002013 WO1997041096A1 (fr) | 1996-04-30 | 1997-04-21 | Nouveaux derives de vitamine d avec des substituants carbocycliques ou heterocycliques en c-25, procede de production desdits derives, produits intermediaires et leur utilisation pour la production de medicaments |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1020042A1 true HK1020042A1 (en) | 2000-03-10 |
Family
ID=7794043
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK99105222A HK1020042A1 (en) | 1996-04-30 | 1999-11-12 | New vitamin derivatives with carbo- or heterocyclic substituents at c-25, a process for their production, intermediate products and their use for producing medicaments. |
Country Status (24)
Country | Link |
---|---|
US (4) | US6642218B2 (fr) |
EP (1) | EP0900198B1 (fr) |
JP (1) | JP2000510826A (fr) |
KR (1) | KR100501589B1 (fr) |
CN (1) | CN1173944C (fr) |
AT (1) | ATE234280T1 (fr) |
AU (1) | AU730394B2 (fr) |
CA (1) | CA2253288A1 (fr) |
CZ (1) | CZ346598A3 (fr) |
DE (2) | DE19619036A1 (fr) |
DK (1) | DK0900198T3 (fr) |
ES (1) | ES2192680T3 (fr) |
HK (1) | HK1020042A1 (fr) |
HU (1) | HUP9901534A3 (fr) |
IL (1) | IL126643A0 (fr) |
NO (1) | NO317752B1 (fr) |
NZ (1) | NZ332488A (fr) |
PL (1) | PL187766B1 (fr) |
PT (1) | PT900198E (fr) |
RU (1) | RU2223954C2 (fr) |
SK (1) | SK283041B6 (fr) |
TW (1) | TW568902B (fr) |
WO (1) | WO1997041096A1 (fr) |
ZA (1) | ZA973757B (fr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5763429A (en) * | 1993-09-10 | 1998-06-09 | Bone Care International, Inc. | Method of treating prostatic diseases using active vitamin D analogues |
US6242434B1 (en) * | 1997-08-08 | 2001-06-05 | Bone Care International, Inc. | 24-hydroxyvitamin D, analogs and uses thereof |
US20020128240A1 (en) * | 1996-12-30 | 2002-09-12 | Bone Care International, Inc. | Treatment of hyperproliferative diseases using active vitamin D analogues |
US6566353B2 (en) * | 1996-12-30 | 2003-05-20 | Bone Care International, Inc. | Method of treating malignancy associated hypercalcemia using active vitamin D analogues |
US20030129194A1 (en) * | 1997-02-13 | 2003-07-10 | Bone Care International, Inc. | Targeted therapeutic delivery of vitamin D compounds |
US6087350A (en) * | 1997-08-29 | 2000-07-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of pretreatment chemicals to enhance efficacy of cytotoxic agents |
DE19744127B4 (de) * | 1997-10-01 | 2006-10-05 | Schering Ag | Neue Vitamin D-Derivate mit Cyclopropylringen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung sowie ihre Verwendung zur Herstellung von Arzneimitteln |
ES2368824T3 (es) | 1998-03-27 | 2011-11-22 | Oregon Health & Science University | Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos. |
DE19935771A1 (de) * | 1999-07-23 | 2001-02-01 | Schering Ag | Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
JP2004504295A (ja) * | 2000-07-18 | 2004-02-12 | ボーン ケア インターナショナル インコーポレイテッド | 安定化1α−ヒドロキシビタミンD |
DE10156596A1 (de) * | 2001-11-13 | 2003-05-28 | Schering Ag | Vitamin D-Derivate mit Acyloxygruppen in der Seitenkette, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
WO2003082800A1 (fr) * | 2002-04-01 | 2003-10-09 | The University Of Alberta | Composes stimulant l'utilisation du glucose et procedes d'utilisation |
US20050074443A1 (en) * | 2003-10-03 | 2005-04-07 | Treadwell Benjamin V. | Methods of attenuating autoimmune disease and compositions useful therefor |
US7094775B2 (en) * | 2004-06-30 | 2006-08-22 | Bone Care International, Llc | Method of treating breast cancer using a combination of vitamin D analogues and other agents |
US20060003950A1 (en) * | 2004-06-30 | 2006-01-05 | Bone Care International, Inc. | Method of treating prostatic diseases using a combination of vitamin D analogues and other agents |
WO2010053165A1 (fr) | 2008-11-04 | 2010-05-14 | 帝人ファーマ株式会社 | Dérivé lactame de vitamine d3 |
US9290447B2 (en) | 2011-05-03 | 2016-03-22 | Wisconsin Alumni Research Foundation | (20R) and (20S)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin D3 analogs and their uses |
WO2012158794A1 (fr) | 2011-05-17 | 2012-11-22 | Wisconsin Alumni Research Foundation | Analogues de n-cyclopropyl-(20r)-2-méthylène-19,26,27-trinor-25-aza-vitamine d et leurs utilisations |
NZ618936A (en) | 2011-07-22 | 2015-07-31 | Venantius Ltd | Indene derivatives for use in the treatment of inflammatory bowel disease |
WO2013174917A1 (fr) * | 2012-05-24 | 2013-11-28 | Venantius Limited | Composés destinés à être utilisés dans le traitement d'une maladie auto-immune inflammatoire |
US10548908B2 (en) | 2016-09-15 | 2020-02-04 | Nostopharma, LLC | Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4851401A (en) * | 1988-07-14 | 1989-07-25 | Wisconsin Alumni Research Foundation | Novel cyclopentano-vitamin D analogs |
DE3933034A1 (de) | 1989-10-02 | 1991-04-11 | Schering Ag | 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung |
DE4003854A1 (de) * | 1990-02-06 | 1991-08-08 | Schering Ag | Seitenketten-homologe vitamin d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel |
US5532228A (en) | 1990-02-06 | 1996-07-02 | Schering Aktiengesellschaft | Side-chain homologous vitamin D derivatives, process for their production, pharmaceutical preparations containing these derivatives and their use as pharmaceutical agents |
NZ245041A (en) * | 1991-11-07 | 1995-03-28 | Res Inst Medicine Chem | Vitamin d analogues and pharmaceutical compositions |
DE4141746A1 (de) | 1991-12-13 | 1993-06-17 | Schering Ag | 20-methyl-substituierte vitamin d-derivate |
DE69214617T2 (de) * | 1991-12-26 | 1997-05-28 | Wisconsin Alumni Res Found | 26,27-Dimethylen-1-Alpha, 25-Dihydroxyvitamin-D2 und 26,27-Dihydroxyvitamin-D2 und Verfahren zu ihrer Herstellung |
DE4200783C2 (de) * | 1992-01-10 | 1997-02-06 | Schering Ag | (5Z,7E,22E)-(1S,3R,24S)-24-Benzyl-9,10-secochola-5,7,10(19),22-tetraen-1,3,24-triol, Verfahren zur Herstellung und Pharmazeutische Präparate |
GB9203535D0 (en) * | 1992-02-19 | 1992-04-08 | Leo Pharm Prod Ltd | Novel treatment iii |
DE4220757A1 (de) | 1992-06-24 | 1994-01-05 | Schering Ag | Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln |
CA2114830C (fr) * | 1993-02-05 | 2000-06-06 | Masayasu Tabe | Compose lactone et procede de production |
GB9309422D0 (en) | 1993-05-07 | 1993-06-23 | Res Inst Medicine Chem | Chemical compounds |
FI96297C (fi) * | 1993-06-24 | 1996-06-10 | Raute Precision Oy | Laitteisto jauhemaisen aineen annostukseen säiliöstä |
NZ271332A (en) * | 1993-07-09 | 2001-03-30 | Theramex | Vitamin D analogues and pharmaceutical use |
GB9314400D0 (en) * | 1993-07-12 | 1993-08-25 | Leo Pharm Prod Ltd | Produktionsaktieselskab) chemical compounds |
GB9315253D0 (en) * | 1993-07-23 | 1993-09-08 | Res Inst Medicine Chem | Chemical compounds |
GB9325415D0 (en) * | 1993-12-13 | 1994-02-16 | Res Inst Medicine Chem | Chemical compounds |
GB9405715D0 (en) * | 1994-03-23 | 1994-05-11 | Res Inst Medicine Chem | Chemical compounds |
DE4411557A1 (de) * | 1994-04-02 | 1995-10-05 | Henkel Kgaa | Verfahren zur Herstellung von Mikroemulsionen |
ATE205190T1 (de) | 1994-06-07 | 2001-09-15 | Teijin Ltd | Vitamin d3-derivate und ein verfahren zu ihrer herstellung |
US5877168A (en) * | 1995-02-10 | 1999-03-02 | Chugai Seiyaku Kabushiki Kaisha | Vitamin D derivative with substituent at the 2β-position |
HUP9801059A3 (en) | 1995-06-14 | 1999-05-28 | Schering Ag | Vitamin d derivatives with c-25 substituents, process for their preparation, intermediate products and their use in preparing medicaments |
US5945410A (en) * | 1997-03-17 | 1999-08-31 | Wisconsin Alumni Research Foundation | 2-alkyl-19-nor-vitamin D compounds |
US6100294A (en) * | 1997-05-16 | 2000-08-08 | Women And Infants Hospital | Cyclic ether vitamin D3 compounds, 1α(OH) 3-epi-vitamin D3 compounds and uses thereof |
-
1996
- 1996-04-30 DE DE19619036A patent/DE19619036A1/de not_active Withdrawn
-
1997
- 1997-04-21 AT AT97921683T patent/ATE234280T1/de not_active IP Right Cessation
- 1997-04-21 DE DE59709509T patent/DE59709509D1/de not_active Expired - Fee Related
- 1997-04-21 WO PCT/EP1997/002013 patent/WO1997041096A1/fr not_active Application Discontinuation
- 1997-04-21 JP JP09538533A patent/JP2000510826A/ja not_active Ceased
- 1997-04-21 CN CNB971942161A patent/CN1173944C/zh not_active Expired - Fee Related
- 1997-04-21 EP EP97921683A patent/EP0900198B1/fr not_active Expired - Lifetime
- 1997-04-21 AU AU27666/97A patent/AU730394B2/en not_active Ceased
- 1997-04-21 SK SK1464-98A patent/SK283041B6/sk unknown
- 1997-04-21 RU RU98121426/04A patent/RU2223954C2/ru not_active IP Right Cessation
- 1997-04-21 US US09/180,018 patent/US6642218B2/en not_active Expired - Fee Related
- 1997-04-21 PL PL32959797A patent/PL187766B1/pl not_active IP Right Cessation
- 1997-04-21 KR KR10-1998-0708698A patent/KR100501589B1/ko not_active IP Right Cessation
- 1997-04-21 HU HU9901534A patent/HUP9901534A3/hu unknown
- 1997-04-21 CA CA002253288A patent/CA2253288A1/fr not_active Abandoned
- 1997-04-21 ES ES97921683T patent/ES2192680T3/es not_active Expired - Lifetime
- 1997-04-21 CZ CZ983465A patent/CZ346598A3/cs unknown
- 1997-04-21 DK DK97921683T patent/DK0900198T3/da active
- 1997-04-21 IL IL12664397A patent/IL126643A0/xx not_active IP Right Cessation
- 1997-04-21 PT PT97921683T patent/PT900198E/pt unknown
- 1997-04-21 NZ NZ332488A patent/NZ332488A/xx unknown
- 1997-04-30 TW TW086105733A patent/TW568902B/zh not_active IP Right Cessation
- 1997-04-30 ZA ZA973757A patent/ZA973757B/xx unknown
-
1998
- 1998-10-29 NO NO19985038A patent/NO317752B1/no unknown
-
1999
- 1999-11-12 HK HK99105222A patent/HK1020042A1/xx not_active IP Right Cessation
-
2000
- 2000-10-25 US US09/695,137 patent/US6600058B1/en not_active Expired - Fee Related
- 2000-10-25 US US09/695,091 patent/US6613920B1/en not_active Expired - Fee Related
-
2003
- 2003-09-10 US US10/658,326 patent/US7211680B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1020042A1 (en) | New vitamin derivatives with carbo- or heterocyclic substituents at c-25, a process for their production, intermediate products and their use for producing medicaments. | |
ATE160783T1 (de) | Gallensäurederivate, verfahren zu ihrer herstellung und verwendung dieser verbindungen als arzneimittel | |
TW334432B (en) | Tricyclic amide and urea compounds | |
HUT54126A (en) | Pesticidal and plant growth regulating composition and process for producing the heterocyclic dione derivatives used as active ingredient | |
PL352476A1 (en) | Novel derivatives of piperazinylalkylthiopyrimidine, parmacological compositions containing tese compounds and method of obtaining active substance | |
HU9802143D0 (en) | New heterocyclic compounds of 5 members in the ring, process for producing them and pharmaceutical compositions containing them | |
CA2153549A1 (fr) | Nouveau derive de benzothiadiazine, son procede de preparation et les compositions pharmeceutiques qui le contiennent | |
DE59909917D1 (de) | Diphenyl-substituierte 5-ring-heterocyclen, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel | |
ATE353321T1 (de) | Dreiringige verbindungen, verfahren zu ihrer herstellung und zwischenprodukte dieses verfahren,ihre anwendung als arzneimittel und sie enthaltende pharmazeutische zusammensetzungen | |
ATE139777T1 (de) | 20-21-dinoreburnamenin-derivate, verfahren zu ihrer herstellung und zwischenverbindungen, ihre anwendung als arzneimittel und diese enthaltende zusammenstellungen | |
HUT62268A (en) | Herbicidal compositions comprising benzene derivatives substituted with heterocyclic group and process for producing the active ingredients | |
NO950665L (no) | Nye polyjoderte forbindelser, fremgangsmåte for deres fremstilling og kontrastmidler inneholdende disse | |
AU3814800A (en) | Enantiomers of mercapto lactones and processes for their synthesis | |
CA2149007A1 (fr) | Derives du cyclohexane, procede de preparation et utilisation de ces composes a des fins therapeutiques | |
PL345966A1 (en) | N-substituted azabicycloheptane derivatives, production and use thereof | |
BG103737A (en) | Method for the preparation of derivatives of 4h-4-oxo-quinolysine-3-carboxylic acid | |
ATE501158T1 (de) | Neue 2-halogen-derivate von 5-o- desosaminylerythronolid a, verfahren zu deren herstellung sowie deren verwendung als arzneimittel | |
IT1258788B (it) | Derivati solforati di acidi biliari | |
CA2144293A1 (fr) | Derives de substitution du propane; methode de preparation; utilisation de ces composes pour le traitement de maladies | |
ATE73128T1 (de) | Ein neues antibiotikum, fumifungin, ein mikrobielles verfahren zu seiner herstellung und seine verwendung als arzneimittel. | |
HUT76859A (en) | 4-halo-2-fluoro-5-alkoxybenzoyl derivatives, process for preparing such compounds and intermediates thereof | |
DE69706441D1 (de) | Tetracyclische aromatische retinoide verbindungen, ihre herstellung und verwendung | |
DE3766967D1 (de) | Cyclohexenonderivate, verfahren zu ihrer herstellung und ihre verwendung als herbizide und das pflanzenwachstum regulierende mittel. | |
IL140863A0 (en) | Novel 2,3,3a,4,9,9a hexahydro-8-hydroxy-1h-benz [f] indoles, a method for the production thereof and their use as medicaments | |
CA2039909A1 (fr) | 3-thialkylflavones et 3-oxalkylflavones substituees, methode pour les preparer, leurs usages, les medicaments fabriques a partir de ces composes et leurs intermediaires |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20090421 |