HK1008347A1 - Dorsal tissue affecting factor and compositions - Google Patents

Dorsal tissue affecting factor and compositions

Info

Publication number
HK1008347A1
HK1008347A1 HK98109178A HK98109178A HK1008347A1 HK 1008347 A1 HK1008347 A1 HK 1008347A1 HK 98109178 A HK98109178 A HK 98109178A HK 98109178 A HK98109178 A HK 98109178A HK 1008347 A1 HK1008347 A1 HK 1008347A1
Authority
HK
Hong Kong
Prior art keywords
compositions
affecting factor
tissue affecting
dorsal tissue
factors
Prior art date
Application number
HK98109178A
Other languages
English (en)
Inventor
David M Valenzuela
Richard M Harland
Nancy Y Ip
William C Smith
George D Yancopoulos
Henryk Cudny
Teresa Lamb
Anne Knecht
Original Assignee
Regeneron Pharma
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma, Univ California filed Critical Regeneron Pharma
Publication of HK1008347A1 publication Critical patent/HK1008347A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK98109178A 1992-09-03 1998-07-15 Dorsal tissue affecting factor and compositions HK1008347A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US93995492A 1992-09-03 1992-09-03
US95041092A 1992-09-23 1992-09-23
US95740192A 1992-10-06 1992-10-06
PCT/US1993/008326 WO1994005791A2 (en) 1992-09-03 1993-09-02 Dorsal tissue affecting factor and compositions

Publications (1)

Publication Number Publication Date
HK1008347A1 true HK1008347A1 (en) 1999-05-07

Family

ID=27420696

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98109178A HK1008347A1 (en) 1992-09-03 1998-07-15 Dorsal tissue affecting factor and compositions

Country Status (9)

Country Link
US (4) US5843775A (xx)
EP (1) EP0656062B1 (xx)
JP (1) JP3431153B2 (xx)
AT (1) ATE190352T1 (xx)
AU (1) AU676847B2 (xx)
DE (1) DE69328025T2 (xx)
HK (1) HK1008347A1 (xx)
IL (2) IL106894A0 (xx)
WO (1) WO1994005791A2 (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994005791A2 (en) * 1992-09-03 1994-03-17 Regeneron Pharmaceuticals, Inc. Dorsal tissue affecting factor and compositions
US5679783A (en) * 1994-11-22 1997-10-21 The Regents Of The University Of California DNA encoding a tissue differentiation affecting factor
US6133232A (en) * 1996-06-20 2000-10-17 The Regents Of The University Of California Endoderm, cardiac and neural inducing factors
AU6267098A (en) * 1997-02-05 1998-08-25 Regents Of The University Of California, The Morphogenic proteins
JP4357003B2 (ja) * 1997-02-19 2009-11-04 リジェネロン ファーマシューティカルズ，インコーポレイテッド 形態形成タンパク質
US6075007A (en) * 1997-07-17 2000-06-13 Regeneron Pharmaceuticals, Inc. Modified noggin polypeptide and compositions
WO1999061044A1 (en) * 1998-05-28 1999-12-02 The Board Of Trustees Of The University Of Arkansas Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption
US6087168A (en) 1999-01-20 2000-07-11 Cedars Sinai Medical Center Conversion of non-neuronal cells into neurons: transdifferentiation of epidermal cells
AU3667100A (en) * 1999-04-23 2000-11-10 Sulzer Orthopedics Ltd Composition for enhancing functional recovery of a mammal from central and/or peripheral nervous system injury of traumatic or pathological origin
CA2411914C (en) * 2000-06-20 2012-08-21 Es Cell International Pte Ltd Method of controlling differentiation of embryonic stem (es) cells by culturing es cells in the presence of bmp-2 pathway antagonists
US20020159986A1 (en) * 2001-01-12 2002-10-31 John Langenfeld Bone morphogenetic protein-2 in the treatment and diagnosis of cancer
WO2002087632A1 (en) * 2001-05-02 2002-11-07 Metaprobe, Inc. High throughput screening methods using magnetic resonance imaging agents
US20030134790A1 (en) * 2002-01-11 2003-07-17 University Of Medicine And Dentistry Of New Jersey Bone Morphogenetic Protein-2 And Bone Morphogenetic Protein-4 In The Treatment And Diagnosis Of Cancer
GB2385052A (en) * 2002-02-05 2003-08-13 Leuven K U Res & Dev Treatment of spondyloarthropathies
AU2006289667A1 (en) * 2005-09-08 2007-03-15 Apollo Life Sciences Limited Noggin and chimeric molecules thereof
KR101163171B1 (ko) 2009-01-20 2012-07-19 (주)케어젠 노긴?유래 펩타이드 및 그의 용도
WO2010147803A2 (en) * 2009-06-08 2010-12-23 Regents Of The University Of Michigan Adult cerebellum-derived neural stem cells and compositions and methods for producing oligodendrocytes
JP2016530243A (ja) * 2013-07-18 2016-09-29 アン アンド ロバート エイチ．ルリー チルドレンズ ホスピタル オブ シカゴ 神経管欠損症を検出及び治療する組成物及び方法
US10179111B2 (en) * 2014-03-07 2019-01-15 University of Pittsburgh—of the Commonwealth System of Higher Education Treating soft tissue via controlled drug release
AT521641B1 (de) * 2018-09-12 2020-07-15 Fianostics Gmbh Verfahren zur Diagnose von Lebererkrankungen

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0171407B1 (en) * 1984-01-30 1993-11-18 Imperial Cancer Research Technology Limited Improvements relating to growth factors
EP0218692A4 (en) * 1985-04-11 1988-03-22 Childrens Medical Center VON WILLEBRAND FACTOR.
US5030576A (en) * 1986-04-30 1991-07-09 Genentech, Inc. Receptors for efficient determination of ligands and their antagonists or agonists
US4857637A (en) * 1986-05-07 1989-08-15 Genentech, Inc. Methods and compositions for immunologically modulating growth hormone receptor activity
US5219759A (en) * 1987-04-22 1993-06-15 Chiron Corporation Recombinant DNA encoding PDGF A-chain polypeptide and expression vectors
US5229500A (en) * 1989-08-30 1993-07-20 Regeneron Pharmaceuticals, Inc. Brain derived neurotrophic factor
US5177197A (en) * 1990-02-27 1993-01-05 Ludwig Institute For Cancer Research Isolated nucleotide sequence expressing human transforming growth factor-β1-binding protein
AU654302B2 (en) * 1990-09-25 1994-11-03 Genentech Inc. Novel neurothrophic factor
US5364769A (en) * 1990-09-25 1994-11-15 Genentech, Inc. Nucleic acid encoding neurotrophic factor four (NT-4), vectors, host cells and methods of production
CA2122491A1 (en) * 1991-10-31 1993-05-13 Herbert Y. Lin Tgf-.beta. type receptor cdnas and uses therefor
KR100259827B1 (ko) * 1991-11-04 2000-06-15 브루스 엠. 에이센, 토마스 제이 데스로저 재조합 골형태 형성 단백질 헤테로다이머, 그 조성물 및 사용방법
WO1994005791A2 (en) * 1992-09-03 1994-03-17 Regeneron Pharmaceuticals, Inc. Dorsal tissue affecting factor and compositions

Also Published As

Publication number Publication date
DE69328025T2 (de) 2000-11-02
IL134656A (en) 2006-12-10
ATE190352T1 (de) 2000-03-15
EP0656062B1 (en) 2000-03-08
US5843775A (en) 1998-12-01
IL106894A0 (en) 1994-05-30
JP3431153B2 (ja) 2003-07-28
US6277593B1 (en) 2001-08-21
DE69328025D1 (de) 2000-04-13
US5821124A (en) 1998-10-13
WO1994005791A3 (en) 1994-07-07
US20020102643A1 (en) 2002-08-01
EP0656062A1 (en) 1995-06-07
AU676847B2 (en) 1997-03-27
WO1994005791A2 (en) 1994-03-17
AU4846593A (en) 1994-03-29
JPH08504086A (ja) 1996-05-07

Similar Documents

Publication Publication Date Title
HK1008347A1 (en) Dorsal tissue affecting factor and compositions
IL134042A0 (en) Modified dorsal tissue affecting factor and compositions
UA43348C2 (uk) Водна фармацевтична композиція, що включає фактор росту нерва (варіанти) та ліофілізований фармацевтичний склад
IL80495A0 (en) Microbial compositions,their production and their use for treating soil
GR3032628T3 (en) NEW GROWTH/DIFFERENTIATION FACTOR OF THE TGF--g(b) FAMILY
UA39158C2 (uk) Похідні n4-оксикарбоніл-5'-дезокси-5-фторцитидину та фармацевтичний препарат на їх основі
GR3024597T3 (en) 7-deazapurine modified oligonucleotides
MY106705A (en) Composites and methods for making same.
AU8547691A (en) Protein sequence-specific oligonucleotide sequences
DE69905170D1 (en) Thiazolopyrimidinderivate
ZA977240B (en) Novel benzamidines
NZ507350A (en) Semi-synthetic ecteinascidins and use in treatment of tumors
IL98134A0 (en) Single chain t-receptors,nucleic acid sequences coding therefor and pharmaceutical compositions containing the same
MX9704030A (es) 1,1-dioxidos de 2-heterocicliloxi y tiometil-1,2,5-tiadiazolidin-3-ona y composiciones y metodo de uso de los mismos.
KR0180256B1 (en) Bpc peptides, their preparation and use
MY128260A (en) Cyclopentane-and-pentene-b-amino acids
IL98273A0 (en) Dna sequences,proteins having esterase activity coded by them,and use of such proteins
MX9806041A (es) Proteina purificada sr-p70.
IL139604A0 (en) Novel peptides
MX9700624A (es) Azolidinonas de imidazopiridina.
PL345204A1 (en) Compounds with growth hormone releasing properties
PE20399A1 (es) Muteina ob
EP0584365A4 (en) NEW AGENT FOR HAIR GROWTH AND GROWTH.
CA2143442A1 (en) Dorsal tissue affecting factor and compositions
IL142579A0 (en) Compounds with growth hormone releasing properties

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110902