GR850716B - - Google Patents

Info

Publication number
GR850716B
GR850716B GR850716A GR850100716A GR850716B GR 850716 B GR850716 B GR 850716B GR 850716 A GR850716 A GR 850716A GR 850100716 A GR850100716 A GR 850100716A GR 850716 B GR850716 B GR 850716B
Authority
GR
Greece
Application number
GR850716A
Other languages
Greek (el)
Inventor
Roland Dr Wenger
Rene P Dr Traber
Hans Dr Kobel
Hans Hofmann
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848407618A external-priority patent/GB8407618D0/en
Priority claimed from GB848411922A external-priority patent/GB8411922D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of GR850716B publication Critical patent/GR850716B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • C07K7/645Cyclosporins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/19Antibiotic
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/27Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GR850716A 1984-03-23 1985-03-21 GR850716B (en:Method)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848407618A GB8407618D0 (en) 1984-03-23 1984-03-23 Organic compounds
GB848411922A GB8411922D0 (en) 1984-05-10 1984-05-10 Organic compounds

Publications (1)

Publication Number Publication Date
GR850716B true GR850716B (en:Method) 1985-07-19

Family

ID=26287502

Family Applications (1)

Application Number Title Priority Date Filing Date
GR850716A GR850716B (en:Method) 1984-03-23 1985-03-21

Country Status (24)

Country Link
US (1) US4639434A (en:Method)
JP (1) JPH08838B2 (en:Method)
AT (1) AT388737B (en:Method)
BE (1) BE901980A (en:Method)
CA (1) CA1247546A (en:Method)
CH (1) CH667274A5 (en:Method)
CS (1) CS249542B2 (en:Method)
DE (1) DE3509809A1 (en:Method)
DK (1) DK128285A (en:Method)
ES (1) ES8702926A1 (en:Method)
FI (1) FI851120L (en:Method)
FR (1) FR2561651B1 (en:Method)
GB (1) GB2155936B (en:Method)
GR (1) GR850716B (en:Method)
HU (1) HU200786B (en:Method)
IL (1) IL74681A (en:Method)
IT (1) IT1199962B (en:Method)
LU (1) LU85819A1 (en:Method)
NL (1) NL8500828A (en:Method)
NO (1) NO851160L (en:Method)
NZ (1) NZ211526A (en:Method)
PH (2) PH21868A (en:Method)
PT (1) PT80149B (en:Method)
SE (1) SE461334B (en:Method)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CY1915A (en) 1984-10-04 1985-09-27 Sandoz Ag Cyclosporins
US4798823A (en) * 1987-06-03 1989-01-17 Merck & Co., Inc. New cyclosporin analogs with modified "C-9 amino acids"
ES2059558T3 (es) * 1987-06-17 1994-11-16 Sandoz Ag Ciclosporins y su uso como productos farmaceuticos.
EP0373260B1 (en) * 1987-06-22 1994-03-09 Merck & Co. Inc. Cyclosporin derivatives with modified "8-amino acid"
US5227467A (en) * 1987-08-03 1993-07-13 Merck & Co., Inc. Immunosuppressive fluorinated cyclosporin analogs
JPH0667850B2 (ja) * 1987-09-03 1994-08-31 ユニバーシティ オブ ジョージア リサーチ ファウンデーション,インコーポレイテッド 眼科用サイクロスポリン組成物
US4839342A (en) * 1987-09-03 1989-06-13 University Of Georgia Research Foundation, Inc. Method of increasing tear production by topical administration of cyclosporin
US5089390A (en) * 1987-09-04 1992-02-18 Syntex (U.S.A.) Inc. 2-methyl-4-hexene- and 2-methyl-4-heptene-1,2-diol derivatives
US5236899A (en) * 1987-11-16 1993-08-17 Merck & Co., Inc. 6-position cyclosporin a analogs as modifiers of cytotoxic drug resistance
US4914188A (en) * 1987-11-16 1990-04-03 Merck & Co., Inc. Novel 6-position cyclosporin analogs as non-immunosuppressive antagonists of cyclosporin binding to cyclophilin
CH679119A5 (en:Method) * 1988-05-13 1991-12-31 Sandoz Ag
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
US5540931A (en) * 1989-03-03 1996-07-30 Charles W. Hewitt Methods for inducing site-specific immunosuppression and compositions of site specific immunosuppressants
GB8916901D0 (en) 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
US5122511A (en) * 1990-02-27 1992-06-16 Merck & Co., Inc. Immunosuppressive cyclosporin analogs with modified amino acids at position-8
US5202310A (en) * 1990-06-06 1993-04-13 Levy Gary A Cyclosporine metabolites
SK278808B6 (sk) * 1990-11-02 1998-03-04 Novartis Ag Cyklosporíny, ich použitie pri príprave liečiva na
EP0487289B1 (en) 1990-11-20 1996-09-04 BEHRINGWERKE Aktiengesellschaft Cyclosporin immunoassay
US5747330A (en) * 1996-06-05 1998-05-05 Poli Industria Chimica Antibiotic producing microbe
RU2170741C2 (ru) * 1996-08-16 2001-07-20 Новартис Аг Способ получения циклоспорина
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
KR100585348B1 (ko) 1997-10-08 2006-06-01 이소테크니카 인코포레이티드 중수소화된 시클로스포린 유사체 및 면역조절제로서 그의용도
US5990274A (en) * 1997-11-25 1999-11-23 Dade Behring Inc. Cyclosporine derivatives and uses thereof
US7449544B2 (en) * 1999-11-30 2008-11-11 Cyclacel Limited p21 peptides
DK1435910T3 (da) * 2001-10-19 2009-11-09 Isotechnika Inc Nye cyclosporinanaloge mikroemulsionsprækoncentrater
DE60213115T2 (de) 2001-10-19 2007-02-01 Isotechnika, Inc., Edmonton Synthese von cyclosporinanaloga
WO2004082629A2 (en) * 2003-03-17 2004-09-30 Albany Molecular Research, Inc. Novel cyclosporins
EP1809656A4 (en) * 2004-09-29 2009-03-25 Amr Technology Inc CYCLOSPORINAL KINANALOGA AND ITS PHARMACEUTICAL APPLICATIONS
JP2008514702A (ja) * 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド 新規シクロスポリン類似体およびそれらの薬学的使用
WO2006041631A2 (en) * 2004-10-06 2006-04-20 Amr Technology, Inc. Novel cyclosporin alkynes and their utility as pharmaceutical agents
US7696166B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US7696165B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7576057B2 (en) 2006-11-20 2009-08-18 Scynexis, Inc. Cyclic peptides
KR102011339B1 (ko) 2010-12-15 2019-08-16 콘트라빌 파마슈티컬스, 인코퍼레이티드 아미노산 1 및 3에서 변형된 사이클로스포린 유사체 분자
PT2683406T (pt) 2011-03-11 2019-07-08 Beth Israel Deaconess Medical Ct Inc Anticorpos anti-cd40 e utilização dos mesmos
CN104877013B (zh) * 2015-06-03 2018-04-20 兰州大学 环孢菌素t及其制备方法和应用
KR20250007054A (ko) 2015-09-04 2025-01-13 프리마토프 테라퓨틱스 인크. 인간화 항-cd40 항체 및 그의 용도

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57140753A (en) * 1981-01-09 1982-08-31 Sandoz Ag Novel cyclosporine
US4384996A (en) * 1981-01-09 1983-05-24 Sandoz Ltd. Novel cyclosporins

Also Published As

Publication number Publication date
CH667274A5 (de) 1988-09-30
ES541465A0 (es) 1987-01-16
DK128285A (da) 1985-09-24
DK128285D0 (da) 1985-03-21
GB2155936B (en) 1987-09-16
FI851120A7 (fi) 1985-09-24
PH21868A (en) 1988-03-25
HUT38370A (en) 1986-05-28
LU85819A1 (fr) 1985-12-12
IT8547852A0 (it) 1985-03-22
PT80149B (en) 1987-03-23
PH23357A (en) 1989-07-14
NL8500828A (nl) 1985-10-16
SE8501392D0 (sv) 1985-03-21
FI851120L (fi) 1985-09-24
IT1199962B (it) 1989-01-05
BE901980A (fr) 1985-09-23
NZ211526A (en) 1988-08-30
HU200786B (en) 1990-08-28
SE8501392L (sv) 1985-09-24
SE461334B (sv) 1990-02-05
GB8507270D0 (en) 1985-04-24
JPH08838B2 (ja) 1996-01-10
ES8702926A1 (es) 1987-01-16
DE3509809A1 (de) 1986-01-09
FI851120A0 (fi) 1985-03-20
JPS60215700A (ja) 1985-10-29
IL74681A (en) 1989-09-10
CS249542B2 (en) 1987-03-12
ATA86385A (de) 1989-01-15
CA1247546A (en) 1988-12-28
GB2155936A (en) 1985-10-02
FR2561651B1 (fr) 1990-03-09
AT388737B (de) 1989-08-25
NO851160L (no) 1985-09-24
IT8547852A1 (it) 1986-09-22
PT80149A (en) 1985-04-01
FR2561651A1 (fr) 1985-09-27
US4639434A (en) 1987-01-27
IL74681A0 (en) 1985-06-30

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