GR79163B - - Google Patents

Info

Publication number
GR79163B
GR79163B GR73216A GR830173216A GR79163B GR 79163 B GR79163 B GR 79163B GR 73216 A GR73216 A GR 73216A GR 830173216 A GR830173216 A GR 830173216A GR 79163 B GR79163 B GR 79163B
Authority
GR
Greece
Application number
GR73216A
Inventor
George Sidney Sach
Original Assignee
Smithkline And French Lab Limi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838322347A external-priority patent/GB8322347D0/en
Application filed by Smithkline And French Lab Limi filed Critical Smithkline And French Lab Limi
Publication of GR79163B publication Critical patent/GR79163B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
GR73216A 1982-12-14 1983-12-12 GR79163B (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8235590 1982-12-14
GB838322347A GB8322347D0 (en) 1983-08-19 1983-08-19 Pyridine derivatives

Publications (1)

Publication Number Publication Date
GR79163B true GR79163B (el) 1984-10-02

Family

ID=26284681

Family Applications (1)

Application Number Title Priority Date Filing Date
GR73216A GR79163B (el) 1982-12-14 1983-12-12

Country Status (8)

Country Link
US (2) US4532252A (el)
EP (1) EP0112142B1 (el)
AU (1) AU2222083A (el)
DE (1) DE3381674D1 (el)
DK (1) DK572583A (el)
ES (3) ES527994A0 (el)
GR (1) GR79163B (el)
PT (1) PT77808B (el)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW7683A1 (en) * 1982-03-29 1984-01-04 Bristol Myers Co Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine h2 receptor antagonist activity
AU2222083A (en) * 1982-12-14 1984-06-21 Smith Kline & French Laboratories Limited Pyridine derivatives
PT78358B (en) * 1983-04-07 1986-05-30 Smith Kline French Lab Chemical process
US4728648A (en) * 1985-02-09 1988-03-01 Smith Kline & French Laboratories Limited Histamine antagonist triadiazole derivatives, compositions, and method of use therefor
CA1286297C (en) * 1985-06-13 1991-07-16 George S. Sach Pyridine derivatives
GB8610867D0 (en) * 1986-05-02 1986-06-11 Smith Kline French Lab 3-hydroxypyridines
IE960442L (en) * 1988-12-27 1990-06-27 Takeda Chemical Industries Ltd Guanidine derivatives, their production and insecticides
US5872139A (en) * 1996-06-17 1999-02-16 American Home Products Corporation Heterocyclymethylamino derivatives of cyclobutene-3,4-diones
WO1997048682A1 (en) * 1996-06-17 1997-12-24 American Home Products Corporation Heterocyclylmethylamino derivatives of cyclobutene-3,4-diones as potassium channel modulators
ATE422203T1 (de) * 2002-10-09 2009-02-15 Schering Corp Thiadiazoldioxide und thiadiazoloxide als cxc- und cc-chemokinrezeptor liganden
US7338968B2 (en) * 2003-12-19 2008-03-04 Schering Corporation Thiadiazoles AS CXC- and CC- chemokine receptor ligands
CA2550540A1 (en) * 2003-12-22 2005-07-28 Schering Corporation Isothiazole dioxides as cxc- and cc- chemokine receptor ligands
ATE432921T1 (de) * 2004-12-23 2009-06-15 Gpc Biotech Ag Quadratsäurederivate mit antiproliferativer wirkung
ES2353401T3 (es) * 2005-06-29 2011-03-01 Schering Corporation Oxidiazolopirazinas y tiadiazolopirazinas 5,6-di-sustituidas como ligandos del receptor de cxc-quimiocina.
JP2009500334A (ja) * 2005-06-29 2009-01-08 シェーリング コーポレイション Ｃｘｃ−ケモカインレセプターリガンドとしてのジ置換オキサジアゾール
US8450348B2 (en) * 2007-02-21 2013-05-28 Forma Tm, Llc Derivatives of squaric acid with anti-proliferative activity

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3535328A (en) * 1967-09-01 1970-10-20 Exxon Research Engineering Co Certain substituted aminothioethoxy pyridines
US3968216A (en) * 1969-10-29 1976-07-06 Smith Kline & French Laboratories Limited Method of inhibiting histamine activity with guanidine compounds
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
GB1421792A (en) * 1973-05-17 1976-01-21 Smith Kline French Lab Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them
GB1497260A (en) * 1974-06-28 1978-01-05 Smith Kline French Lab Guanidine derivatives
IL49528A (en) * 1975-05-21 1980-11-30 Smith Kline French Lab Imidazolyl(or thiazolyl)methylthio(or butyl)guanidine or thiourea derivatives,their preparation and pharmaceutical compositions comprising them
US4120973A (en) * 1975-07-31 1978-10-17 Smithkline & French Laboratories Limited Imidazolyl alkylaminocyclobutenediones
GB1595291A (en) * 1976-09-21 1981-08-12 Smith Kline French Lab Pyrimidone and thiopyrimidone derivatives
US4210658A (en) * 1977-09-08 1980-07-01 Smith Kline & French Laboratories Limited Amidinosulphonic acid derivatives
ZA792608B (en) * 1978-05-30 1980-06-25 Smith Kline French Lab Nitro compounds
IL57415A (en) * 1978-05-30 1984-08-31 Smith Kline French Lab Nitropyrrole compounds,process for preparing them and pharmaceutical compositions containing them
US4250316A (en) * 1978-11-24 1981-02-10 Bristol-Myers Company Pyridyl guanidine anti-ulcer agents
US4394508A (en) * 1980-06-07 1983-07-19 Bristol-Myers Company Chemical compounds
US4380639A (en) * 1981-03-03 1983-04-19 Bristol-Myers Company Substituted 1,2,5-thiadiazole derivatives
US4390701A (en) * 1981-05-18 1983-06-28 Bristol-Myers Company 1-Amino-2-[3-(3-piperidinomethylphenoxy)propylamino]cyclobutene-3,4-dione
US4503051A (en) * 1981-05-18 1985-03-05 Bristol-Myers Company Substituted 3-cyclobutene-1,2-diones, pharmaceutical compositions thereof and methods of use
ZW7683A1 (en) * 1982-03-29 1984-01-04 Bristol Myers Co Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine h2 receptor antagonist activity
US4528375A (en) * 1982-03-29 1985-07-09 Bristol-Myers Company Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
GB2131683B (en) * 1982-12-11 1986-03-12 Alma Ruby Skelcher Walking aid foot device
AU2222083A (en) * 1982-12-14 1984-06-21 Smith Kline & French Laboratories Limited Pyridine derivatives
DE3374007D1 (en) * 1982-12-23 1987-11-12 Smith Kline French Lab Pyridine derivatives
US4440933A (en) * 1983-03-16 1984-04-03 Bristol-Myers Company Process for preparing 1,2,5-thiadiazoles

Also Published As

Publication number Publication date
AU2222083A (en) 1984-06-21
DE3381674D1 (de) 1990-07-26
EP0112142A3 (en) 1986-01-15
US4640926A (en) 1987-02-03
DK572583A (da) 1984-06-15
PT77808A (en) 1984-01-01
PT77808B (en) 1986-03-26
ES8600245A1 (es) 1985-10-01
DK572583D0 (da) 1983-12-13
US4532252A (en) 1985-07-30
ES527994A0 (es) 1985-10-01
EP0112142B1 (en) 1990-06-20
ES8607241A1 (es) 1986-05-16
EP0112142A2 (en) 1984-06-27
ES8605513A1 (es) 1986-03-16
ES543728A0 (es) 1986-03-16
ES543729A0 (es) 1986-05-16

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