GR3036958T3 - Use of 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine for the treatment of pain and dema. - Google Patents
Use of 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine for the treatment of pain and dema.Info
- Publication number
- GR3036958T3 GR3036958T3 GR20010401827T GR20010401827T GR3036958T3 GR 3036958 T3 GR3036958 T3 GR 3036958T3 GR 20010401827 T GR20010401827 T GR 20010401827T GR 20010401827 T GR20010401827 T GR 20010401827T GR 3036958 T3 GR3036958 T3 GR 3036958T3
- Authority
- GR
- Greece
- Prior art keywords
- dichlorophenyl
- diamino
- triazine
- dema
- pain
- Prior art date
Links
- PYZRQGJRPPTADH-UHFFFAOYSA-N lamotrigine Chemical compound NC1=NC(N)=NN=C1C1=CC=CC(Cl)=C1Cl PYZRQGJRPPTADH-UHFFFAOYSA-N 0.000 title abstract 2
- QZIQJVCYUQZDIR-UHFFFAOYSA-N mechlorethamine hydrochloride Chemical compound Cl.ClCCN(C)CCCl QZIQJVCYUQZDIR-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929203483A GB9203483D0 (en) | 1992-02-19 | 1992-02-19 | Anti-inflammatory compounds |
| PCT/GB1993/000341 WO1993016700A1 (en) | 1992-02-19 | 1993-02-18 | Use of 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine for the treatment of pain and ×dema |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3036958T3 true GR3036958T3 (en) | 2002-01-31 |
Family
ID=10710643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR20010401827T GR3036958T3 (en) | 1992-02-19 | 2001-10-22 | Use of 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine for the treatment of pain and dema. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5712277A (https=) |
| EP (1) | EP0626851B1 (https=) |
| KR (1) | KR950700067A (https=) |
| AT (1) | ATE204476T1 (https=) |
| AU (1) | AU684711B2 (https=) |
| CA (1) | CA2129043C (https=) |
| CY (1) | CY2299B1 (https=) |
| DE (1) | DE69330638T2 (https=) |
| DK (1) | DK0626851T3 (https=) |
| ES (1) | ES2162813T3 (https=) |
| GB (2) | GB9203483D0 (https=) |
| GR (1) | GR3036958T3 (https=) |
| IL (1) | IL104775A (https=) |
| MX (1) | MX9300927A (https=) |
| NZ (1) | NZ249197A (https=) |
| PT (1) | PT626851E (https=) |
| TW (1) | TW226331B (https=) |
| WO (1) | WO1993016700A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9424766D0 (en) * | 1994-12-07 | 1995-02-08 | Wellcome Found | Pharmaceutical composition |
| EP0800520B1 (en) * | 1994-12-30 | 2002-06-19 | The Wellcome Foundation Limited | Process for the preparation of lamotrigine |
| GB9625795D0 (en) * | 1996-12-12 | 1997-01-29 | Smithkline Beecham Plc | Novel treatment |
| GB9726987D0 (en) | 1997-12-22 | 1998-02-18 | Glaxo Group Ltd | Compounds |
| DK1169060T3 (da) * | 1999-04-09 | 2006-01-16 | Euro Celtique Sa | Natriumkanalblokkerpræparater og anvendelse deraf |
| DK1423168T3 (da) * | 2001-09-03 | 2006-05-15 | Newron Pharm Spa | Farmaceutisk præparat omfattende gabapentin eller en analog deraf og et alfa-aminoamid og dets analgetiske anvendelse |
| DK1809271T5 (da) * | 2004-09-10 | 2010-12-06 | Newron Pharm Spa | Anvendelse af (R)-(halogenbenzyloxy)benzylaminopropanamider som natrium- og/eller calciumkanalselektive modulatorer |
| EP3307273B1 (en) * | 2015-06-12 | 2020-12-09 | University of Greenwich | Triazine derivatives as interferon-gamma inhibitors |
| US12605388B2 (en) | 2024-09-25 | 2026-04-21 | Azurity Pharmaceuticals Ireland Limited | Lamotrigine salts, co-crystals, and compositions |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3637688A (en) * | 1970-01-09 | 1972-01-25 | American Home Prod | 6-(fluoro and trifluoromethyl phenyl)-3 5-diamino - 1 2 4 - triazines and substituted - 6 - phenylalkyl-3,5-diamino-1 2 4-triazines |
| US4310551A (en) * | 1979-03-19 | 1982-01-12 | Diamond Shamrock Corporation | Pharmacologically active substituted 1,2,4-triazines |
| DK153787C (da) * | 1979-06-01 | 1989-01-16 | Wellcome Found | Analogifremgangsmaade til fremstilling af substituerede 3,5-diamino-6-phenyl-1,2,4-triaziner og alfa-cyanobenzyliden-aminoguanidinforbindelser til anvendelse som mellemprodukter herved |
| GB8613183D0 (en) * | 1986-05-30 | 1986-07-02 | Wellcome Found | Triazine salt |
| GB9012312D0 (en) * | 1990-06-01 | 1990-07-18 | Wellcome Found | Pharmacologically active cns compounds |
-
1992
- 1992-02-19 GB GB929203483A patent/GB9203483D0/en active Pending
-
1993
- 1993-02-18 TW TW082101145A patent/TW226331B/zh active
- 1993-02-18 PT PT93904225T patent/PT626851E/pt unknown
- 1993-02-18 AU AU35092/93A patent/AU684711B2/en not_active Ceased
- 1993-02-18 AT AT93904225T patent/ATE204476T1/de not_active IP Right Cessation
- 1993-02-18 WO PCT/GB1993/000341 patent/WO1993016700A1/en not_active Ceased
- 1993-02-18 ES ES93904225T patent/ES2162813T3/es not_active Expired - Lifetime
- 1993-02-18 KR KR1019940702885A patent/KR950700067A/ko not_active Withdrawn
- 1993-02-18 DE DE69330638T patent/DE69330638T2/de not_active Expired - Fee Related
- 1993-02-18 CA CA002129043A patent/CA2129043C/en not_active Expired - Fee Related
- 1993-02-18 IL IL10477593A patent/IL104775A/xx not_active IP Right Cessation
- 1993-02-18 NZ NZ249197A patent/NZ249197A/en unknown
- 1993-02-18 GB GB9414348A patent/GB2277265B/en not_active Revoked
- 1993-02-18 DK DK93904225T patent/DK0626851T3/da active
- 1993-02-18 EP EP93904225A patent/EP0626851B1/en not_active Expired - Lifetime
- 1993-02-19 MX MX9300927A patent/MX9300927A/es not_active IP Right Cessation
-
1996
- 1996-07-15 US US08/680,111 patent/US5712277A/en not_active Expired - Fee Related
-
2001
- 2001-10-22 GR GR20010401827T patent/GR3036958T3/el not_active IP Right Cessation
-
2002
- 2002-10-14 CY CY0200058A patent/CY2299B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB2277265B (en) | 1996-01-10 |
| MX9300927A (es) | 1994-08-31 |
| TW226331B (https=) | 1994-07-11 |
| ES2162813T3 (es) | 2002-01-16 |
| CA2129043C (en) | 2004-01-27 |
| JP3713271B2 (ja) | 2005-11-09 |
| GB9203483D0 (en) | 1992-04-08 |
| DE69330638D1 (de) | 2001-09-27 |
| US5712277A (en) | 1998-01-27 |
| CA2129043A1 (en) | 1993-09-02 |
| KR950700067A (ko) | 1995-01-16 |
| NZ249197A (en) | 1997-05-26 |
| AU3509293A (en) | 1993-09-13 |
| GB9414348D0 (en) | 1994-09-07 |
| ATE204476T1 (de) | 2001-09-15 |
| IL104775A0 (en) | 1993-06-10 |
| AU684711B2 (en) | 1998-01-08 |
| PT626851E (pt) | 2002-02-28 |
| CY2299B1 (en) | 2003-07-04 |
| JPH07503968A (ja) | 1995-04-27 |
| GB2277265A (en) | 1994-10-26 |
| EP0626851B1 (en) | 2001-08-22 |
| IL104775A (en) | 1997-02-18 |
| DK0626851T3 (da) | 2001-12-03 |
| DE69330638T2 (de) | 2002-06-27 |
| EP0626851A1 (en) | 1994-12-07 |
| WO1993016700A1 (en) | 1993-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ML | Lapse due to non-payment of fees |