GR3026432T3 - Use of N,N'-bis 3-(ethylamino)propyl -1,7-heptanediamine and a cytotoxic agent - Google Patents

Use of N,N'-bis 3-(ethylamino)propyl -1,7-heptanediamine and a cytotoxic agent

Info

Publication number
GR3026432T3
GR3026432T3 GR980400622T GR980400622T GR3026432T3 GR 3026432 T3 GR3026432 T3 GR 3026432T3 GR 980400622 T GR980400622 T GR 980400622T GR 980400622 T GR980400622 T GR 980400622T GR 3026432 T3 GR3026432 T3 GR 3026432T3
Authority
GR
Greece
Prior art keywords
antineoplastic
heptanediamine
ethylamino
propyl
bis
Prior art date
Application number
GR980400622T
Other languages
English (en)
Inventor
Nellikunja J Prakash
Terry L Bowlin
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of GR3026432T3 publication Critical patent/GR3026432T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GR980400622T 1990-12-13 1998-03-20 Use of N,N'-bis 3-(ethylamino)propyl -1,7-heptanediamine and a cytotoxic agent GR3026432T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62681490A 1990-12-13 1990-12-13

Publications (1)

Publication Number Publication Date
GR3026432T3 true GR3026432T3 (en) 1998-06-30

Family

ID=24511975

Family Applications (1)

Application Number Title Priority Date Filing Date
GR980400622T GR3026432T3 (en) 1990-12-13 1998-03-20 Use of N,N'-bis 3-(ethylamino)propyl -1,7-heptanediamine and a cytotoxic agent

Country Status (11)

Country Link
EP (1) EP0490380B1 (el)
JP (1) JPH04275233A (el)
KR (1) KR100195423B1 (el)
AT (1) ATE163264T1 (el)
AU (1) AU648846B2 (el)
DE (1) DE69128926T2 (el)
DK (1) DK0490380T3 (el)
ES (1) ES2113870T3 (el)
GR (1) GR3026432T3 (el)
IE (1) IE914331A1 (el)
ZA (1) ZA919695B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5910485A (en) * 1996-01-31 1999-06-08 Japan Science And Technology Corporation Antitumor agents comprising as the principal compounds containing silicon and nitrogen
US6274561B1 (en) 1997-01-29 2001-08-14 Japan Science & Technology Corp. Antitumor agents comprising as the principal compounds containing silicon and nitrogen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ223340A (en) * 1987-02-03 1991-03-26 Merrell Dow Pharma Polyamine derivatives and pharmaceutical compositions
EP0378146B1 (en) * 1989-01-10 1995-03-29 Merrell Pharmaceuticals Inc. Polyamine derivatives as antineoplastic agents
ZA903804B (en) * 1989-05-23 1991-03-27 Merrell Dow Pharma A method of potentiating cell-mediated immunity utilizing polyamine derivatives

Also Published As

Publication number Publication date
AU648846B2 (en) 1994-05-05
ZA919695B (en) 1992-09-30
ATE163264T1 (de) 1998-03-15
ES2113870T3 (es) 1998-05-16
KR920011481A (ko) 1992-07-24
DE69128926D1 (de) 1998-03-26
JPH04275233A (ja) 1992-09-30
EP0490380A2 (en) 1992-06-17
DE69128926T2 (de) 1998-06-04
EP0490380B1 (en) 1998-02-18
EP0490380A3 (en) 1993-03-10
IE914331A1 (en) 1992-06-17
AU8890791A (en) 1992-06-18
DK0490380T3 (da) 1998-09-23
KR100195423B1 (ko) 1999-06-15

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