GR3019673T3 - Methods for detecting glucagon antagonists - Google Patents

Methods for detecting glucagon antagonists

Info

Publication number
GR3019673T3
GR3019673T3 GR960401050T GR960401050T GR3019673T3 GR 3019673 T3 GR3019673 T3 GR 3019673T3 GR 960401050 T GR960401050 T GR 960401050T GR 960401050 T GR960401050 T GR 960401050T GR 3019673 T3 GR3019673 T3 GR 3019673T3
Authority
GR
Greece
Prior art keywords
glucagon
methods
response pathway
glucagon antagonists
stimulation
Prior art date
Application number
GR960401050T
Other languages
English (en)
Inventor
Robert A Smith
James R Piggott
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/741,931 external-priority patent/US5408037A/en
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of GR3019673T3 publication Critical patent/GR3019673T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
GR960401050T 1991-01-17 1996-04-19 Methods for detecting glucagon antagonists GR3019673T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64134391A 1991-01-17 1991-01-17
US07/741,931 US5408037A (en) 1991-01-17 1991-08-08 Methods for detecting glucagon antagonists
PCT/US1992/000346 WO1992012998A1 (en) 1991-01-17 1992-01-14 Methods for detecting glucagon antagonists

Publications (1)

Publication Number Publication Date
GR3019673T3 true GR3019673T3 (en) 1996-07-31

Family

ID=24571964

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960401050T GR3019673T3 (en) 1991-01-17 1996-04-19 Methods for detecting glucagon antagonists

Country Status (10)

Country Link
EP (1) EP0567562B1 (el)
JP (1) JPH06504913A (el)
AT (1) ATE135372T1 (el)
AU (2) AU663861B2 (el)
CA (1) CA2100874A1 (el)
DE (1) DE69209052T2 (el)
DK (1) DK0567562T3 (el)
ES (1) ES2085004T3 (el)
GR (1) GR3019673T3 (el)
WO (1) WO1992012998A1 (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992004042A1 (en) * 1990-08-31 1992-03-19 The Rockefeller University Glucagon analogs with asp9 replacements or deletions
US5510459A (en) * 1991-01-17 1996-04-23 Zymogenetics, Inc. Glucagon antagonists
US5408037A (en) * 1991-01-17 1995-04-18 Zymogenetics, Inc. Methods for detecting glucagon antagonists
AU689078B2 (en) * 1992-08-28 1998-03-26 Novo Nordisk A/S Glucagon receptors
US5776725A (en) * 1992-08-28 1998-07-07 Zymogenetics, Inc. Recombinant production of glucagon receptors
US5480867A (en) * 1993-12-29 1996-01-02 The Rockefeller University Glucagon analogs with serine replacements
AR036711A1 (es) * 2001-10-05 2004-09-29 Bayer Corp Peptidos que actuan como agonistas del receptor del glp-1 y como antagonistas del receptor del glucagon y sus metodos de uso farmacologico
KR20110040760A (ko) * 2008-06-17 2011-04-20 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 대사 질환 및 비만 치료용 ｇｉｐ-기초된 혼합형 항진제

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879273A (en) * 1987-05-22 1989-11-07 The Rockefeller University Glucagon homologs and therapeutic use thereof
EP0397834B1 (en) * 1988-10-28 2000-02-02 Genentech, Inc. Method for identifying active domains and amino acid residues in polypeptides and hormone variants

Also Published As

Publication number Publication date
DE69209052T2 (de) 1996-11-14
CA2100874A1 (en) 1992-07-18
AU663861B2 (en) 1995-10-26
AU1200392A (en) 1992-08-27
DE69209052D1 (de) 1996-04-18
JPH06504913A (ja) 1994-06-09
AU673648B2 (en) 1996-11-14
AU3047595A (en) 1995-12-07
WO1992012998A1 (en) 1992-08-06
DK0567562T3 (da) 1996-07-29
ATE135372T1 (de) 1996-03-15
EP0567562B1 (en) 1996-03-13
EP0567562A1 (en) 1993-11-03
ES2085004T3 (es) 1996-05-16

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