GR3015206T3 - Arylpyrazole derivatives as platelet aggregation inhibitors. - Google Patents

Arylpyrazole derivatives as platelet aggregation inhibitors.

Info

Publication number
GR3015206T3
GR3015206T3 GR940403971T GR940403971T GR3015206T3 GR 3015206 T3 GR3015206 T3 GR 3015206T3 GR 940403971 T GR940403971 T GR 940403971T GR 940403971 T GR940403971 T GR 940403971T GR 3015206 T3 GR3015206 T3 GR 3015206T3
Authority
GR
Greece
Prior art keywords
hydrogen
platelet aggregation
integer
aggregation inhibitors
inhibitors
Prior art date
Application number
GR940403971T
Other languages
English (en)
Inventor
Nicholas Andrew Meanwell
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of GR3015206T3 publication Critical patent/GR3015206T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
GR940403971T 1989-07-31 1995-02-28 Arylpyrazole derivatives as platelet aggregation inhibitors. GR3015206T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38774989A 1989-07-31 1989-07-31
US07/523,637 US4994482A (en) 1989-07-31 1990-05-10 Arylpyrazol derivatives as anti-platelet agents, compositions and use

Publications (1)

Publication Number Publication Date
GR3015206T3 true GR3015206T3 (en) 1995-05-31

Family

ID=27012007

Family Applications (1)

Application Number Title Priority Date Filing Date
GR940403971T GR3015206T3 (en) 1989-07-31 1995-02-28 Arylpyrazole derivatives as platelet aggregation inhibitors.

Country Status (13)

Country Link
US (1) US4994482A (el)
EP (1) EP0417449B1 (el)
JP (1) JP2939909B2 (el)
AT (1) ATE118485T1 (el)
AU (1) AU630991B2 (el)
CA (1) CA2022183C (el)
DE (1) DE69016894T2 (el)
DK (1) DK0417449T3 (el)
ES (1) ES2067601T3 (el)
FI (1) FI104169B1 (el)
GR (1) GR3015206T3 (el)
IE (1) IE66600B1 (el)
PT (1) PT94856B (el)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374712A (en) * 1989-12-20 1994-12-20 Case Western Reserve University Imidazopyridinium compound and processes for isolating, identifying, and chemically synthesizing same
US5155126A (en) * 1990-03-20 1992-10-13 E. I. Du Pont De Nemours And Company Treatment of central nervous system disorders with pyrazole, pyrrole and triazole angiotensin-II receptor antagonists
DE4330959A1 (de) * 1993-09-09 1995-03-16 Schering Ag Neue Benzimidazolderivate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
DE19649460A1 (de) * 1996-11-26 1998-05-28 Bayer Ag Neue substituierte Pyrazolderivate
DE19904391A1 (de) * 1999-02-04 2000-08-10 Bayer Ag Pyrazol-Alkylamide

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ178996A (en) * 1974-11-15 1978-06-02 Kornis G Pyrfazole amides and thioamides;herbicidal compositions
CA1098527A (en) * 1976-12-20 1981-03-31 Denis M. Bailey 1-amino-lower-alkyl-3,4-diphenyl-1h-pyrazoles
DE3228271A1 (de) * 1982-07-29 1984-02-02 A. Nattermann & Cie GmbH, 5000 Köln Triphenylimidazolyloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4826868A (en) * 1986-05-29 1989-05-02 Ortho Pharmaceutical Corporation 1,5-Diaryl-3-substituted pyrazoles pharmaceutical compositions and use
IL86926A (en) * 1987-07-13 1992-07-15 Sterling Drug Inc Diphenyl-1h-pyrazole-1-alkanamides,their preparation and antiarrhythmic compositions containing them
US4898880A (en) * 1989-03-22 1990-02-06 Sterling Drug Inc. N-(heterocycle)alkyl)-1H-pyrazole-1-alkanamides as antiarrhythmic agents, compositions and use
US4916150A (en) * 1989-03-22 1990-04-10 Sterling Drug Inc. 1H-pyrazole-1-alkanamines antiarrhythmic compositions and use

Also Published As

Publication number Publication date
JP2939909B2 (ja) 1999-08-25
CA2022183C (en) 2000-07-18
AU630991B2 (en) 1992-11-12
FI903741A0 (fi) 1990-07-26
CA2022183A1 (en) 1991-02-01
DK0417449T3 (da) 1995-04-03
PT94856A (pt) 1991-03-20
AU5997090A (en) 1991-01-31
JPH0381265A (ja) 1991-04-05
EP0417449A1 (en) 1991-03-20
IE902757A1 (en) 1991-02-27
PT94856B (pt) 1997-03-31
US4994482A (en) 1991-02-19
IE66600B1 (en) 1996-01-24
DE69016894T2 (de) 1995-06-08
ES2067601T3 (es) 1995-04-01
FI104169B (fi) 1999-11-30
FI104169B1 (fi) 1999-11-30
DE69016894D1 (de) 1995-03-23
EP0417449B1 (en) 1995-02-15
ATE118485T1 (de) 1995-03-15

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