GR3004426T3 - - Google Patents

Info

Publication number
GR3004426T3
GR3004426T3 GR920400790T GR920400790T GR3004426T3 GR 3004426 T3 GR3004426 T3 GR 3004426T3 GR 920400790 T GR920400790 T GR 920400790T GR 920400790 T GR920400790 T GR 920400790T GR 3004426 T3 GR3004426 T3 GR 3004426T3
Authority
GR
Greece
Prior art keywords
alkyl
carbon atoms
independently
stereochemistry
arylalkyl
Prior art date
Application number
GR920400790T
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GR3004426T3 publication Critical patent/GR3004426T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
GR920400790T 1986-08-21 1992-04-21 GR3004426T3 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/898,570 US4694002A (en) 1986-08-21 1986-08-21 Benzothiazepine derivatives

Publications (1)

Publication Number Publication Date
GR3004426T3 true GR3004426T3 (el) 1993-03-31

Family

ID=25409650

Family Applications (1)

Application Number Title Priority Date Filing Date
GR920400790T GR3004426T3 (el) 1986-08-21 1992-04-21

Country Status (8)

Country Link
US (1) US4694002A (el)
EP (1) EP0262373B1 (el)
JP (1) JPS6351381A (el)
AT (1) ATE72242T1 (el)
CA (1) CA1338417C (el)
DE (1) DE3776478D1 (el)
ES (1) ES2028008T3 (el)
GR (1) GR3004426T3 (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2607004B1 (fr) * 1986-11-20 1990-06-01 Synthelabo Compositions pharmaceutiques contenant du diltiazem et un inhibiteur de l'enzyme de conversion de l'angiotensine
US4871731A (en) * 1987-10-07 1989-10-03 Marion Laboratories, Inc. Captopril and diltiazem composition and the like
US5008411A (en) * 1988-05-24 1991-04-16 Hoffmann-La Roche Inc. Glycidic acid ester and process of preparation
US5037821A (en) * 1988-06-01 1991-08-06 E. R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing a calcium channel blocker alone or in combination with an ACE inhibitor
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
DE3990664T1 (de) * 1988-06-20 1991-04-25 Squibb & Sons Inc Benzazepin- und benzothiazepin-derivate
AU4807790A (en) * 1988-12-05 1990-06-26 Houston Biotechnology Incorporated Therapeutic use of calcium entry blockers in retinal or optic nerve dysfunction
US4952692A (en) * 1989-04-04 1990-08-28 E. R. Squibb & Sons, Inc. Benzazepine derivatives
US4946840A (en) * 1989-04-06 1990-08-07 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
FR2645744B1 (fr) * 1989-04-13 1994-01-21 Roussel Uclaf Derives de la benzothiazepine, leur procede de preparation et les intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant
US5559017A (en) * 1989-08-09 1996-09-24 E. R. Squibb & Sons, Inc. Microbial reduction of benzazepines and benzothiazepine derivatives
US5001236A (en) * 1989-11-22 1991-03-19 Marion Laboratories, Inc. Benzothiazepines
WO2010022259A1 (en) * 2008-08-22 2010-02-25 Milestone Pharmaceuticals Inc. Short acting benzothiazepine calcium channel blockers and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3075967A (en) * 1961-06-12 1963-01-29 Olin Mathieson Benzothiazines
GB2017080B (en) * 1978-02-14 1982-07-21 Maruko Pharmaceutical Co Benzothiazepines
US4552695A (en) * 1983-04-21 1985-11-12 Shionogi & Co., Ltd. Process for production of diltiazem hydrochloride
US4590188A (en) * 1984-02-18 1986-05-20 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivatives and their pharmaceutical use

Also Published As

Publication number Publication date
US4694002A (en) 1987-09-15
JPS6351381A (ja) 1988-03-04
ES2028008T3 (es) 1992-07-01
EP0262373B1 (en) 1992-01-29
CA1338417C (en) 1996-06-25
EP0262373A1 (en) 1988-04-06
DE3776478D1 (de) 1992-03-12
ATE72242T1 (de) 1992-02-15

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