GR3002754T3 - Seamless soft capsule - Google Patents

Seamless soft capsule

Info

Publication number
GR3002754T3
GR3002754T3 GR91401365T GR910401365T GR3002754T3 GR 3002754 T3 GR3002754 T3 GR 3002754T3 GR 91401365 T GR91401365 T GR 91401365T GR 910401365 T GR910401365 T GR 910401365T GR 3002754 T3 GR3002754 T3 GR 3002754T3
Authority
GR
Greece
Prior art keywords
stream
composite jet
film
forming
soft capsule
Prior art date
Application number
GR91401365T
Other languages
Greek (el)
Inventor
Tadashi Kosaka
Kazuki Omata
Tatsuo Hashimoto
Teruaki Yamazaki
Kazuo Hayashi
Tomiya Hosoi
Kenichi Ikuta
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Publication of GR3002754T3 publication Critical patent/GR3002754T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use

Abstract

A soft capsule composed of a plurality of cells coalesced to each other and filling substances encapsulated in the individual cells, the wall of at least one of the cells being formed of a material different from a material forming the wall of at least one of the other cells, and said capsule being seamless. The soft capsule can be produced by (a) preparing a plurality of composite jet streams each consisting of a stream of a film-forming liquid substance for forming a cell wall and within said stream of a film-forming liquid substance a single stream, or a plurality of independent streams, of a filling substance having flowability, the film-forming liquid subtance in at least one of the composite jet streams being different from the film-forming liquid substance in at least one of the other composite jet streams, (b) advancing the plurality of composite jet streams in closely spaced relationship into and through a stream of a liquid medium substantially incapable of dissolving the film-forming liquid substance in the flowing direction of the liquid medium stream, (c) coalescing the adjacent composite jet streams to each other to form a single composite jet stream in the liquid medium stream, (d) cutting the single composite jet stream to a predetermined length successively from its leading end in the liquid medium stream, and (e) solidifying the cell walls of the resulting soft capsule.
GR91401365T 1985-12-26 1991-09-19 Seamless soft capsule GR3002754T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP29718285 1985-12-26

Publications (1)

Publication Number Publication Date
GR3002754T3 true GR3002754T3 (en) 1993-01-25

Family

ID=17843233

Family Applications (1)

Application Number Title Priority Date Filing Date
GR91401365T GR3002754T3 (en) 1985-12-26 1991-09-19 Seamless soft capsule

Country Status (6)

Country Link
EP (1) EP0228067B1 (en)
JP (1) JPH06104193B2 (en)
AT (1) ATE67401T1 (en)
DE (1) DE3681572D1 (en)
ES (1) ES2024418B3 (en)
GR (1) GR3002754T3 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0585368T3 (en) * 1991-04-25 1998-03-16 Univ Brown Res Found Implantable biocompatible immuno-insulating vehicle for delivery of selected therapeutic products
US5800829A (en) * 1991-04-25 1998-09-01 Brown University Research Foundation Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
GB2338896B (en) 1998-07-02 2003-05-21 Reckitt & Colmann Prod Ltd Chewable Capsules
IL147826A0 (en) 1999-07-30 2002-08-14 Smithkline Beecham Plc Multi-component pharmaceutical dosage form
CN1109627C (en) * 2000-01-26 2003-05-28 依钟康 Soft capsule for packing different material and its production equipment and method
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
GB0102342D0 (en) 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US7670612B2 (en) 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
JP5105705B2 (en) * 2002-05-09 2012-12-26 中外製薬株式会社 Light-stabilized soft capsule
US7025911B2 (en) 2002-09-13 2006-04-11 Freund Corporation Manufacturing method for oral quick-dissolving seamless capsule
JP2004105282A (en) * 2002-09-13 2004-04-08 Freunt Ind Co Ltd Method for producing seamless capsule immediately melting in buccal cavity
JP2006521366A (en) * 2003-03-28 2006-09-21 シグモイド・バイオテクノロジーズ・リミテッド Solid oral dosage forms containing seamless microcapsules
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
JP4051075B2 (en) * 2003-11-07 2008-02-20 フロイント産業株式会社 Seamless capsule manufacturing method, seamless capsule manufacturing apparatus, and seamless capsule
AR048033A1 (en) 2004-03-12 2006-03-22 Smithkline Beecham Plc PHARMACEUTICAL COMPOSITION TO MOLD COMPONENTS THAT INCLUDE COPOLIMERO OF POLY (MET) ACRYLATE, COVER, CONNECTOR OR SPACER OF CAPSULA MOLDED BY INJECTION THAT HAS THE PHARMACEUTICAL COMPOSITION AND FORM OF PHARMACEUTICAL MULTI-COMPONENT COMPONENTS
US20070134493A1 (en) * 2005-12-08 2007-06-14 Kanji Meghpara Compositions and capsules with stable hydrophilic layers
JP5183104B2 (en) * 2006-06-19 2013-04-17 森下仁丹株式会社 Multiple soft capsules for bad breath removal
WO2008018019A2 (en) * 2006-08-09 2008-02-14 Koninklijke Philips Electronics N. V. A device for and a method of activating a physiologically effective substance by ultrasonic waves, and a capsule
JP2009119148A (en) * 2007-11-16 2009-06-04 Freunt Ind Co Ltd Apparatus and method for producing multi-color seamless capsule
EP2781156B1 (en) * 2011-11-16 2017-06-14 Morishita Jintan Co., Ltd. Insect pest repellent
JP6091679B1 (en) * 2016-03-29 2017-03-08 株式会社松風 Droplet generator

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59131355A (en) * 1983-01-17 1984-07-28 森下仁丹株式会社 Multiple soft capsule
JPS60109520A (en) * 1983-11-16 1985-06-15 Fujisawa Pharmaceut Co Ltd Multilocular soft capsule agent
JPS61151119A (en) * 1984-12-24 1986-07-09 Taisho Pharmaceut Co Ltd Seamless capsule

Also Published As

Publication number Publication date
DE3681572D1 (en) 1991-10-24
ATE67401T1 (en) 1991-10-15
EP0228067A3 (en) 1988-06-01
JPH06104193B2 (en) 1994-12-21
ES2024418B3 (en) 1992-03-01
JPS62234542A (en) 1987-10-14
EP0228067A2 (en) 1987-07-08
EP0228067B1 (en) 1991-09-18

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