GR21272B - METHOD OF PREPARATION OF PIPERIDINE PRODUCERS. - Google Patents
METHOD OF PREPARATION OF PIPERIDINE PRODUCERS.Info
- Publication number
- GR21272B GR21272B GR600121272A GR600121272A GR21272B GR 21272 B GR21272 B GR 21272B GR 600121272 A GR600121272 A GR 600121272A GR 600121272 A GR600121272 A GR 600121272A GR 21272 B GR21272 B GR 21272B
- Authority
- GR
- Greece
- Prior art keywords
- degrees celsius
- organic acid
- preparation
- propin
- radical
- Prior art date
Links
Landscapes
- Hydrogenated Pyridines (AREA)
Abstract
έθοδος παρασκευής αλάτων των εστέρων της (προπιν-2'-υλο-1')-4-πιπεριδινόλης -(4) αντιστοιχούντων είς τον γενικόν τύπον (Ι) εις τον οποίον το R παριστά ευθείαν μονοσθενή άλυσιν αλειφατικής υδρογονανθρακικής ρίζης από C1 έως C4, αλκοξυαλκυλομάδα, φαινοξυαλκυλομάδα κυκλοαλειφατικήν ή ευθείαν ή διακεκλαδισμένην αλκυλαρωματικήν ρίζαν, το R1 παριστά ρίζαν οργανικού οξέος και το ΗΧ οργανικό ή ανόργανονοξύ. Είς την μέθοδον ταύτην αντιδρά έν προπιν-2-υλο-1 αλίδιον, παρουσία μαγνησίου, αργιλλιου ή ψευδαργύρου και αιθήρ τις, είς θερμοκρασίαν μεταξύ -10βαθμούς κελσίου και 50 βαθμούς κελσίου, μετά μιάςΝ-υποκατεστημένης πιπεριδόνης. Το ούτω ληφθέν μεταλλικόν σύμπλοκον δύναται να υδρολυθή και ακολούθως να εστεροποιηθή, ή να εστεροποιηθή απ' ευθείας,είς θερμοκρασίαν 15 βαθμούς κελσίου έως 65 βαθμούς κελσίου, τη βοηθεία ανυδρίτου οργανικού οξέος, καιούτω ο ληφθείς βαικός εσθήρ μετατρέπεται τη βοηθεία οργανικού ή ανοργάνου οξέος είς το αντίστοιχον άλας. process for the preparation of salts of the esters of (propin-2'-yl-1 ') - 4-piperidinol - (4) corresponding to general formula (I) wherein R represents a straight monovalent chain of an aliphatic hydrocarbon radical from C1 to C4, alkoxyalkyl group, phenoxyalkyl group cycloaliphatic or straight or branched alkyl aromatic radical, R1 represents organic acid radical and HX represents organic or inorganic acid. The process is reacted with a propin-2-yl-1 allion in the presence of magnesium, aluminum or zinc and ethers at temperatures between -10 degrees Celsius and 50 degrees Celsius, followed by an N-substituted piperidone. The metal complex thus obtained can be hydrolyzed and then esterified, or esterified directly, at a temperature of 15 degrees Celsius to 65 degrees Celsius, with the help of anhydrous organic acid, so that the obtained organic acid is corresponding salt.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR600121272A GR21272B (en) | 1960-08-06 | 1960-08-06 | METHOD OF PREPARATION OF PIPERIDINE PRODUCERS. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR600121272A GR21272B (en) | 1960-08-06 | 1960-08-06 | METHOD OF PREPARATION OF PIPERIDINE PRODUCERS. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR21272B true GR21272B (en) | 1960-10-12 |
Family
ID=36862290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR600121272A GR21272B (en) | 1960-08-06 | 1960-08-06 | METHOD OF PREPARATION OF PIPERIDINE PRODUCERS. |
Country Status (1)
| Country | Link |
|---|---|
| GR (1) | GR21272B (en) |
-
1960
- 1960-08-06 GR GR600121272A patent/GR21272B/en unknown
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