GR1000496B - Ενδοφλεβιο συστημα για απελευθερωση ευεργετικου παραγοντα. - Google Patents

Ενδοφλεβιο συστημα για απελευθερωση ευεργετικου παραγοντα.

Info

Publication number
GR1000496B
GR1000496B GR900100104A GR900100104A GR1000496B GR 1000496 B GR1000496 B GR 1000496B GR 900100104 A GR900100104 A GR 900100104A GR 900100104 A GR900100104 A GR 900100104A GR 1000496 B GR1000496 B GR 1000496B
Authority
GR
Greece
Prior art keywords
fluid
window
drug
formulator
pct
Prior art date
Application number
GR900100104A
Other languages
English (en)
Other versions
GR900100104A (en
Inventor
Felix Theeuwes
Su Il Yum
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of GR900100104A publication Critical patent/GR900100104A/el
Publication of GR1000496B publication Critical patent/GR1000496B/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1407Infusion of two or more substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Παρέχεται ένας συνταγοποιητής φαρμάκου (30,60) για ένα σετ ενδοφλέβιας χορήγησης (14). Το σετ ενδοφλέβιας χορήγησης (14) περιλαμβάνει ένα περιέκτη (12) ενός IV ρευστού (13), ένα σταγονομετρικό θάλαμο (22), ένα συνταγοποιητή παράγοντα (30,60) και μία διάταξη προσαρμογέα βελόνης (28). Ο συνταγοποιητής παράγοντα (30,60) έχει μία είσοδο ρευστού (23) και μία έξοδο ρευστού (25) για διατήρηση μιας ροής του IV ρευστού (13) δια μέσου αυτού. 'Ενα τμήμα (36) του τοιχώματος (32) του συνταγοποιητού αποτελείται από ένα υλικό παράθυρο το οποίο επιτρέπει στον παράγοντα να διαχέεται δια μέσου αυτού αλλά που παρεμποδίζει εκ μεταφοράς απώλεια του IV ρευστού (13). 'Ενας κατανεμητής ροής (38, 68) παρέχεται εντός του θαλάμου για κατανομή της ροής του IV ρευστού (13) κατά μήκος της εσωτερικής επιφάνειας του παραθύρου (36). Μία διαδερματικού - τύπου συσκευή απελευθέρωσης φαρμάκου (40) προσκολλάται στην εξωτερική επιφάνεια του παραθύρου (36). Το φάρμακο απελευθερώνεται από τη συσκευή απελευθέρωσης 40 δια μέσου του παραθύρου (36) και εντός του ρέοντος IV ρευστού (13). Η συσκευή (40) απελευθερώνει φάρμακο εντός του IV ρευστού (13) με ρυθμό που είναι ανεξάρτητος του ρυθμού ροής του IV ρευστού (13) δια μέσου του συνταγοποιητού (30, 60). Ο ρυθμός απελευθέρωσης φαρμάκου από τη συσκευή (40) εντός του IV ρευστού (13) ελέγχεται είτε από αυτό καθεαυτό το παράθυρο (36) ή από μία στιβάδα μεμβράνης (46) στη συσκευή απελευθέρωσης φαρμάκου (40). Μία πλειονότητα συσκευών απελευθέρωσης φαρμάκου (40) μπορεί να προσαρμόζεται στο παράθυρο (36) για να απελευθερώνεται μία πλειονότητα φαρμάκων ή για να απελευθερώνεται ένα μοναδικό φάρμακο σε υψηλότερο ρυθμό δοσολογίας. 'Ενα ανάλογο παράθυρο (11) μπορεί να τοποθετείται σε ένα IV σάκκο για να απελευθερώνει ένα φάρμακο εντός του IV ρευστού σε αυτό. ω
GR900100104A 1989-02-15 1990-02-14 Ενδοφλεβιο συστημα για απελευθερωση ευεργετικου παραγοντα. GR1000496B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/311,906 US4969871A (en) 1989-02-15 1989-02-15 Intravenous system for delivering a beneficial agent

Publications (2)

Publication Number Publication Date
GR900100104A GR900100104A (en) 1991-06-28
GR1000496B true GR1000496B (el) 1992-07-30

Family

ID=23209012

Family Applications (1)

Application Number Title Priority Date Filing Date
GR900100104A GR1000496B (el) 1989-02-15 1990-02-14 Ενδοφλεβιο συστημα για απελευθερωση ευεργετικου παραγοντα.

Country Status (12)

Country Link
US (2) US4969871A (el)
EP (1) EP0458879B1 (el)
AT (1) ATE90000T1 (el)
AU (1) AU623983B2 (el)
CA (1) CA2009984A1 (el)
DE (1) DE69001812T2 (el)
DK (1) DK0458879T3 (el)
ES (1) ES2041174T3 (el)
GR (1) GR1000496B (el)
NZ (1) NZ232524A (el)
PT (1) PT93152A (el)
WO (1) WO1990009201A1 (el)

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Also Published As

Publication number Publication date
AU5151790A (en) 1990-09-05
EP0458879B1 (en) 1993-06-02
EP0458879A1 (en) 1991-12-04
US4969871A (en) 1990-11-13
PT93152A (pt) 1990-08-31
ATE90000T1 (de) 1993-06-15
NZ232524A (en) 1995-03-28
DK0458879T3 (da) 1993-08-23
GR900100104A (en) 1991-06-28
WO1990009201A1 (en) 1990-08-23
DE69001812T2 (de) 1993-09-23
ES2041174T3 (es) 1993-11-01
AU623983B2 (en) 1992-05-28
CA2009984A1 (en) 1990-08-15
US5160320A (en) 1992-11-03
DE69001812D1 (de) 1993-07-08

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