GB997652A - New quinazolinone derivatives and process for their preparation - Google Patents
New quinazolinone derivatives and process for their preparationInfo
- Publication number
- GB997652A GB997652A GB13195/64A GB1319564A GB997652A GB 997652 A GB997652 A GB 997652A GB 13195/64 A GB13195/64 A GB 13195/64A GB 1319564 A GB1319564 A GB 1319564A GB 997652 A GB997652 A GB 997652A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- acid
- anhydride
- alkyl
- reactive derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- AVRPFRMDMNDIDH-UHFFFAOYSA-N 1h-quinazolin-2-one Chemical class C1=CC=CC2=NC(O)=NC=C21 AVRPFRMDMNDIDH-UHFFFAOYSA-N 0.000 title 1
- 150000008064 anhydrides Chemical class 0.000 abstract 4
- RWZYAGGXGHYGMB-UHFFFAOYSA-N anthranilic acid Chemical compound NC1=CC=CC=C1C(O)=O RWZYAGGXGHYGMB-UHFFFAOYSA-N 0.000 abstract 4
- -1 Phosphorus halides Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002905 orthoesters Chemical class 0.000 abstract 2
- YDWKYECLNLURGV-UHFFFAOYSA-N 1-(2,1-benzoxazol-3-yl)propan-1-one Chemical compound C1=CC=CC2=C(C(=O)CC)ON=C21 YDWKYECLNLURGV-UHFFFAOYSA-N 0.000 abstract 1
- QMNUDYFKZYBWQX-UHFFFAOYSA-N 1H-quinazolin-4-one Chemical class C1=CC=C2C(=O)N=CNC2=C1 QMNUDYFKZYBWQX-UHFFFAOYSA-N 0.000 abstract 1
- TXJUTRJFNRYTHH-UHFFFAOYSA-N 1h-3,1-benzoxazine-2,4-dione Chemical compound C1=CC=C2C(=O)OC(=O)NC2=C1 TXJUTRJFNRYTHH-UHFFFAOYSA-N 0.000 abstract 1
- PXBFMLJZNCDSMP-UHFFFAOYSA-N 2-Aminobenzamide Chemical compound NC(=O)C1=CC=CC=C1N PXBFMLJZNCDSMP-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical class Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 150000007933 aliphatic carboxylic acids Chemical class 0.000 abstract 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052782 aluminium Inorganic materials 0.000 abstract 1
- 239000004411 aluminium Substances 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 229910052796 boron Inorganic materials 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000003840 hydrochlorides Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000000147 hypnotic effect Effects 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 235000021317 phosphate Nutrition 0.000 abstract 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 150000003141 primary amines Chemical class 0.000 abstract 1
- WYVAMUWZEOHJOQ-UHFFFAOYSA-N propionic anhydride Chemical compound CCC(=O)OC(=O)CC WYVAMUWZEOHJOQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH522263A CH430733A (de) | 1963-04-25 | 1963-04-25 | Verfahren zur Herstellung von neuen Chinazolinon-Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB997652A true GB997652A (en) | 1965-07-07 |
Family
ID=4289976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB13195/64A Expired GB997652A (en) | 1963-04-25 | 1964-03-31 | New quinazolinone derivatives and process for their preparation |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3382246A (enExample) |
| BE (1) | BE646988A (enExample) |
| CH (1) | CH430733A (enExample) |
| DE (1) | DE1226105B (enExample) |
| DK (1) | DK111325B (enExample) |
| ES (1) | ES299004A1 (enExample) |
| FR (1) | FR4108M (enExample) |
| GB (1) | GB997652A (enExample) |
| NL (1) | NL6404507A (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992013535A1 (en) * | 1991-02-06 | 1992-08-20 | Research Corporation Technologies, Inc. | Anticonvulsant substituted quinazolones |
| US5283247A (en) * | 1991-02-06 | 1994-02-01 | Research Corporation Technologies, Inc. | Anticonvulsant substituted quinazolones |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3748325A (en) * | 1970-04-06 | 1973-07-24 | Karamchand Premchand Private | Process for the preparation of quinazolinone derivatives |
| US4710502A (en) * | 1985-11-04 | 1987-12-01 | American Cyanamid Company | 3-heteroarylalkyl-4-quinazolinones |
| US4753944A (en) * | 1985-11-04 | 1988-06-28 | American Cyanamid Company | Pharmaceutical methods of using 3-heteroarylalkyl-4-quinazolinones |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2439386A (en) * | 1948-04-13 | Preparation of quinazolones | ||
| US3213094A (en) * | 1965-10-19 | Method of preparing quinazolones | ||
| US3162634A (en) * | 1964-12-22 | Z-methyl-j- | ||
| US2872370A (en) * | 1953-07-22 | 1959-02-03 | Carter Prod Inc | Hypnotic composition containing about 1 to 3 parts acetophenetidin and about 3 to 1 parts salicylamide |
| US3047462A (en) * | 1959-03-06 | 1962-07-31 | Lab Jacques Logeais Soc D Expl | Quinazolone anti-inflammatory composition |
| US3102072A (en) * | 1959-05-30 | 1963-08-27 | Asta Werke Ag Chem Fab | Hypnotic composition comprising barbituric acid derivatives and n,n-disubstituted - beta - aminoisopropyl-(p-chloro-alpha-methyl-benzhydryl)-ethers |
| US3086910A (en) * | 1960-03-09 | 1963-04-23 | Wallace & Tiernan Inc | Central nervous system depressants 3-(2'-pyridyl)-4-quinazolones |
| GB908187A (en) * | 1960-04-21 | 1962-10-17 | Monsanto Chemicals | New quinazolines |
| US3073826A (en) * | 1960-10-20 | 1963-01-15 | Mead Johnson & Co | 3-pyrrolidylmethyl-4-quinazolones |
-
1963
- 1963-04-25 CH CH522263A patent/CH430733A/de unknown
-
1964
- 1964-03-12 DE DEE26598A patent/DE1226105B/de active Pending
- 1964-03-31 GB GB13195/64A patent/GB997652A/en not_active Expired
- 1964-04-16 US US360447A patent/US3382246A/en not_active Expired - Lifetime
- 1964-04-21 ES ES299004A patent/ES299004A1/es not_active Expired
- 1964-04-22 FR FR971892A patent/FR4108M/fr not_active Expired
- 1964-04-22 DK DK198764AA patent/DK111325B/da unknown
- 1964-04-23 BE BE646988A patent/BE646988A/xx unknown
- 1964-04-23 NL NL6404507A patent/NL6404507A/xx unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992013535A1 (en) * | 1991-02-06 | 1992-08-20 | Research Corporation Technologies, Inc. | Anticonvulsant substituted quinazolones |
| US5283247A (en) * | 1991-02-06 | 1994-02-01 | Research Corporation Technologies, Inc. | Anticonvulsant substituted quinazolones |
Also Published As
| Publication number | Publication date |
|---|---|
| FR4108M (enExample) | 1966-04-25 |
| ES299004A1 (es) | 1964-06-16 |
| NL6404507A (enExample) | 1964-10-26 |
| US3382246A (en) | 1968-05-07 |
| DE1226105B (de) | 1966-10-06 |
| CH430733A (de) | 1967-02-28 |
| BE646988A (enExample) | 1964-10-23 |
| DK111325B (da) | 1968-07-29 |
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