GB992330A - Hog cholera serum - Google Patents
Hog cholera serumInfo
- Publication number
- GB992330A GB992330A GB4417762A GB4417762A GB992330A GB 992330 A GB992330 A GB 992330A GB 4417762 A GB4417762 A GB 4417762A GB 4417762 A GB4417762 A GB 4417762A GB 992330 A GB992330 A GB 992330A
- Authority
- GB
- United Kingdom
- Prior art keywords
- virus
- hog cholera
- diarrhea
- pig
- attenuated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 206010008631 Cholera Diseases 0.000 title abstract 5
- 210000002966 serum Anatomy 0.000 title abstract 3
- 241000700605 Viruses Species 0.000 abstract 18
- 206010012735 Diarrhoea Diseases 0.000 abstract 6
- 241000710777 Classical swine fever virus Species 0.000 abstract 4
- 230000002238 attenuated effect Effects 0.000 abstract 3
- 241000283973 Oryctolagus cuniculus Species 0.000 abstract 2
- 241000282887 Suidae Species 0.000 abstract 2
- 238000004113 cell culture Methods 0.000 abstract 2
- 230000000644 propagated effect Effects 0.000 abstract 2
- 210000001519 tissue Anatomy 0.000 abstract 2
- 239000005723 virus inoculator Substances 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 244000309466 calf Species 0.000 abstract 1
- 239000012531 culture fluid Substances 0.000 abstract 1
- 238000011081 inoculation Methods 0.000 abstract 1
- 210000003292 kidney cell Anatomy 0.000 abstract 1
- 230000002085 persistent effect Effects 0.000 abstract 1
- 210000000952 spleen Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Hog cholera serum is prepared by inoculating a pig with virus diarrhea virus and not less than 7 days and preferably about two weeks after the virus diarrhea virus inoculation, the pig is inoculated with hog cholera virus and then, about two to three weeks after the hog cholera virus inoculation, the pig is bled when anti-bodies are present in maximal amounts and the resulting immune blood is converted to immune hog cholera serum. The virus diarrhea virus may be unmodified virus such as is obtained from the spleen of a calf infected with virus diarrhea virus, or virus diarrhea virus propagated in tissue-culture or modified or attenuated virus obtained by passage through rabbits. The hog cholera virus may be unmodified cholera virus maintained by serial passage through pigs; attenuated virus which reverts to virulent p state; tissue propagated virus; attenuated virus obtained by passage through rabbits. The virus diarrhea virus may be produced by serially passing Oregon C24V strain of native virus at least 10, preferably 32 times, through cell cultures of tissue cultured embryonic bovine kidney cells. The hog cholera may be produced by serially passing persistent strain hog cholera virus PAV-1 through cell cultures until inoculations of 1 ml. of culture fluid in non-immune pigs result in a temperature deviation of 1 DEG F. for only one day.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15648861A | 1961-12-01 | 1961-12-01 | |
| US15648761A | 1961-12-01 | 1961-12-01 | |
| US17050162 US3293129A (en) | 1962-02-01 | 1962-02-01 | Immunization of cattle against virus diarrhea virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB992330A true GB992330A (en) | 1965-05-19 |
Family
ID=27387878
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4417762A Expired GB992330A (en) | 1961-12-01 | 1962-11-22 | Hog cholera serum |
Country Status (2)
| Country | Link |
|---|---|
| ES (1) | ES282847A1 (en) |
| GB (1) | GB992330A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6291228B1 (en) | 1988-08-03 | 2001-09-18 | Vericore Limited | Vaccine |
-
1962
- 1962-11-22 GB GB4417762A patent/GB992330A/en not_active Expired
- 1962-11-27 ES ES282847A patent/ES282847A1/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6291228B1 (en) | 1988-08-03 | 2001-09-18 | Vericore Limited | Vaccine |
| US6416764B1 (en) | 1988-08-03 | 2002-07-09 | Vericore Limited | Vaccine |
Also Published As
| Publication number | Publication date |
|---|---|
| ES282847A1 (en) | 1963-05-01 |
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