GB9806929D0 - MEK inhibiting compounds,compositions containing such compounds and methods of treatment - Google Patents

MEK inhibiting compounds,compositions containing such compounds and methods of treatment

Info

Publication number
GB9806929D0
GB9806929D0 GBGB9806929.7A GB9806929A GB9806929D0 GB 9806929 D0 GB9806929 D0 GB 9806929D0 GB 9806929 A GB9806929 A GB 9806929A GB 9806929 D0 GB9806929 D0 GB 9806929D0
Authority
GB
United Kingdom
Prior art keywords
compounds
treatment
methods
compositions containing
mek inhibiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GBGB9806929.7A
Other versions
GB2323845A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9709292.8A external-priority patent/GB9709292D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB9806929D0 publication Critical patent/GB9806929D0/en
Publication of GB2323845A publication Critical patent/GB2323845A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB9806929A 1997-03-31 1998-03-31 MEK inhibiting lactones Withdrawn GB2323845A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4287597P 1997-03-31 1997-03-31
GBGB9709292.8A GB9709292D0 (en) 1997-05-07 1997-05-07 MEK inhibiting compounds,compositions containing such compounds and methods of treatment

Publications (2)

Publication Number Publication Date
GB9806929D0 true GB9806929D0 (en) 1998-05-27
GB2323845A GB2323845A (en) 1998-10-07

Family

ID=26311498

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9806929A Withdrawn GB2323845A (en) 1997-03-31 1998-03-31 MEK inhibiting lactones

Country Status (1)

Country Link
GB (1) GB2323845A (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP377198A0 (en) * 1998-05-28 1998-06-18 Fujisawa Pharmaceutical Co., Ltd. Novel compound WF00144
AU8856201A (en) 2000-09-01 2002-03-13 Andel Inst Van Inhibition of mitogen-activated protein kinase (mapk) pathway: a selective therapeutic strategy against melanoma
WO2002076496A1 (en) * 2001-03-22 2002-10-03 Van Andel Institute Anthrax lethal factor inhibits tumor growth and angiogenesis
DE10130890A1 (en) * 2001-06-27 2003-01-16 Aventis Pharma Gmbh Eurotinones and derivatives thereof, process for their preparation and use thereof
MXPA04008722A (en) 2002-03-08 2005-07-13 Eisai Co Ltd Macrocyclic compounds useful as pharmaceuticals.
US7915306B2 (en) 2002-03-08 2011-03-29 Eisai Co., Ltd. Macrocyclic compounds useful as pharmaceuticals
CA2581375A1 (en) * 2004-09-27 2006-04-06 Kosan Biosciences Incorporated Specific kinase inhibitors
US8546404B2 (en) 2005-12-13 2013-10-01 Merck Sharp & Dohme Compounds that are ERK inhibitors
KR20080103996A (en) 2006-02-16 2008-11-28 쉐링 코포레이션 Pyrrolidine derivatives as erk inhibitors
US7601852B2 (en) * 2006-05-11 2009-10-13 Kosan Biosciences Incorporated Macrocyclic kinase inhibitors
US8609640B2 (en) 2007-07-25 2013-12-17 Eisai, Inc. Multikinase inhibitors for use in the treatment of cancer
MY152271A (en) 2008-02-21 2014-09-15 Merck Sharp & Dohme Novel compounds that are erk inhibitors
JP5651125B2 (en) 2008-12-10 2015-01-07 デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド MEK mutations that confer resistance to MEK inhibitors
BR112012021411A2 (en) 2010-02-25 2017-04-18 Dana Farber Cancer Inst Inc braf mutations that confer resistance to braf inhibitors.
ES2714875T3 (en) 2010-03-09 2019-05-30 Dana Farber Cancer Inst Inc Methods of diagnosis and treatment of cancer in patients presenting or developing resistance to a first cancer therapy
WO2013169858A1 (en) 2012-05-08 2013-11-14 The Broad Institute, Inc. Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy

Also Published As

Publication number Publication date
GB2323845A (en) 1998-10-07

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)