GB973142A - (4-acetyl-1-naphthoxy) propyl esters - Google Patents

(4-acetyl-1-naphthoxy) propyl esters

Info

Publication number
GB973142A
GB973142A GB2450560A GB2450560A GB973142A GB 973142 A GB973142 A GB 973142A GB 2450560 A GB2450560 A GB 2450560A GB 2450560 A GB2450560 A GB 2450560A GB 973142 A GB973142 A GB 973142A
Authority
GB
United Kingdom
Prior art keywords
group
carry
substituent
carboxyl
tri
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2450560A
Inventor
William Hubert Hunter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Priority to GB2450560A priority Critical patent/GB973142A/en
Priority to FR858078A priority patent/FR1051M/en
Priority to BE602322A priority patent/BE602322A/en
Publication of GB973142A publication Critical patent/GB973142A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings

Abstract

The invention comprises esters of the general formula <FORM:0973142/C1/1> (wherein R represents either (a) the group -COR, in which R1 represents a C1-5 alkyl group which may carry a halogen or an o -carboxyl substituent, a phenyl group which may carry a carboxyl or sulphonic substituent, a pyridyl group which may carry a carboxyl substituent, or an amino group, or (b) the group -SO2R2 in which R2 represents a phenyl or tolyl group), and pharmaceutical compositions containing them and a non-toxic carrier, and the preparation of the esters by the processes of the examples, viz. reacting 1-(4-acetyl-1-naphthoxy)-propan-2-ol with an appropriate acid halide or anhydride, or, when R is to be -CONH2, with phosgene followed by reaction of the product with ammonia. The o-sulphobenzoate is isolated in the form of its sodium salt, and the hydrochloride of the nicotinate is described. The pharmaceutical compositions are active as muscle relaxants or anticonvulsants, and may be in forms suitable for injection or for oral administration. According to the Provisional Specification, R may also represent an acyl group, not covered by the definition above, derived from one of the following acids: di- or tri-chloracetic, dimethylaminoacetic, di- or tri-methoxybenzoic, N-methyl- or N-propyl-carbamic, benzilic, furoic, palmitic, oleic or lauric; or from ethyl hydrogen succinate. Specification 969,198 is referred to.
GB2450560A 1960-04-07 1960-07-14 (4-acetyl-1-naphthoxy) propyl esters Expired GB973142A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB2450560A GB973142A (en) 1960-07-14 1960-07-14 (4-acetyl-1-naphthoxy) propyl esters
FR858078A FR1051M (en) 1960-04-07 1961-04-07 Therapeutic agents for use as muscle relaxants and anti-convulsants.
BE602322A BE602322A (en) 1960-04-07 1961-04-07 Therapeutic agents for use as muscle relaxants and anti-convulsants.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2450560A GB973142A (en) 1960-07-14 1960-07-14 (4-acetyl-1-naphthoxy) propyl esters

Publications (1)

Publication Number Publication Date
GB973142A true GB973142A (en) 1964-10-21

Family

ID=10212710

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2450560A Expired GB973142A (en) 1960-04-07 1960-07-14 (4-acetyl-1-naphthoxy) propyl esters

Country Status (1)

Country Link
GB (1) GB973142A (en)

Similar Documents

Publication Publication Date Title
GB808105A (en) New pharmaceutical compositions
ES345981A1 (en) Pyridines and poultry feedstuffs and additives thereof containing pyridines
GB1069069A (en) An aminoalkylethanoanthracene and process for its manufacture
GB861560A (en) N-substituted piperidines
GB859546A (en) Composition for treatment of the skin
GB973142A (en) (4-acetyl-1-naphthoxy) propyl esters
GB1065296A (en) Phenthiazine derivatives
GB1055221A (en) Pyridobenzoxazepine derivatives
GB999583A (en) Pharmaceutical preparations containing trihydroxamic acids
GB972090A (en) New hydrazines and their use
GB842325A (en) Pharmaceutical compositions containing aminoguanidine derivatives
GB964561A (en) New sulphonamides and process for preparing them
GB1124613A (en) ª†-resorcylic acid anilides and process for preparing them
GB808187A (en) Weedkilling compositions
ES382438A1 (en) Pharmaceutical compositions
GB746051A (en) S:s-diethyldithioterephthalate and therapeutic compositions containing the same
GB878432A (en) Therapeutic compositions containing sulphonamides
GB1073521A (en) Indole derivatives
GB971042A (en) New benzotriazole derivatives
GB1012623A (en) 1-chloro-n-sulphonyl-formamidines and process for their manufacture
GB823242A (en) Therapeutic compositions containing choline salts of dialkyl xanthines
GB1157556A (en) Novel Benzazole Derivatives and the Preparation thereof
GB993255A (en) Process for the production of dibenzoazepine derivatives
GB1017450A (en) 2-amino-4-alkoxy-úË-triazines
JPS52254A (en) Process for preparation of secopenicilanic acid amide derivatives