GB9705031D0 - 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives - Google Patents

2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives

Info

Publication number
GB9705031D0
GB9705031D0 GBGB9705031.4A GB9705031A GB9705031D0 GB 9705031 D0 GB9705031 D0 GB 9705031D0 GB 9705031 A GB9705031 A GB 9705031A GB 9705031 D0 GB9705031 D0 GB 9705031D0
Authority
GB
United Kingdom
Prior art keywords
cycloalkyl
carboxylic acid
acid derivatives
substituted benzoyl
benzoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GBGB9705031.4A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Pharmacia and Upjohn SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn SpA filed Critical Pharmacia and Upjohn SpA
Priority to GBGB9705031.4A priority Critical patent/GB9705031D0/en
Publication of GB9705031D0 publication Critical patent/GB9705031D0/en
Priority to EP98910685A priority patent/EP0973720A1/fr
Priority to CN98804144A priority patent/CN1252049A/zh
Priority to AU64979/98A priority patent/AU6497998A/en
Priority to PL98335601A priority patent/PL335601A1/xx
Priority to JP53912398A priority patent/JP2001514634A/ja
Priority to CA002283184A priority patent/CA2283184A1/fr
Priority to KR1019997008184A priority patent/KR20000076096A/ko
Priority to HU0001023A priority patent/HUP0001023A3/hu
Priority to EA199900809A priority patent/EA199900809A1/ru
Priority to IL13167698A priority patent/IL131676A0/xx
Priority to PCT/EP1998/000883 priority patent/WO1998040344A1/fr
Priority to TW087102847A priority patent/TW407146B/zh
Priority to ZA981972A priority patent/ZA981972B/xx
Priority to NO994386A priority patent/NO994386L/no
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/18—Saturated compounds containing keto groups
    • C07C62/20—Saturated compounds containing keto groups with a saturated six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/60—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/82—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/62—Compounds containing any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylcarbamates
    • C07C271/64—Y being a hydrogen or a carbon atom, e.g. benzoylcarbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/51—Y being a hydrogen or a carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/38—Unsaturated compounds containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GBGB9705031.4A 1997-03-11 1997-03-11 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives Pending GB9705031D0 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
GBGB9705031.4A GB9705031D0 (en) 1997-03-11 1997-03-11 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives
PCT/EP1998/000883 WO1998040344A1 (fr) 1997-03-11 1998-02-16 Derives d'acides benzoyle-cycloalkyl-1-carboxyliques-2-substitues
CA002283184A CA2283184A1 (fr) 1997-03-11 1998-02-16 Derives d'acides benzoyle-cycloalkyl-1-carboxyliques-2-substitues
HU0001023A HUP0001023A3 (en) 1997-03-11 1998-02-16 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives
AU64979/98A AU6497998A (en) 1997-03-11 1998-02-16 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives
PL98335601A PL335601A1 (en) 1997-03-11 1998-02-16 Derivatives of 2-substituted benzoylcycloalkyl carboxylic acid
JP53912398A JP2001514634A (ja) 1997-03-11 1998-02-16 ２−置換ベンゾイル−シクロアルキル−１−カルボン酸誘導体
EP98910685A EP0973720A1 (fr) 1997-03-11 1998-02-16 Derives d'acides benzoyle-cycloalkyl-1-carboxyliques-2-substitues
KR1019997008184A KR20000076096A (ko) 1997-03-11 1998-02-16 2-치환된 벤조일-사이클로알킬-1-카복실산 유도체
CN98804144A CN1252049A (zh) 1997-03-11 1998-02-16 2－取代的苯甲酰基－环烷基－1－羧酸衍生物
EA199900809A EA199900809A1 (ru) 1997-03-11 1998-02-16 Производные 2-(замещенный бензоил) циклоакил-1-карбоновой кислоты
IL13167698A IL131676A0 (en) 1997-03-11 1998-02-16 2-Substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives
TW087102847A TW407146B (en) 1997-03-11 1998-02-26 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives having infibition activity to kynurenine-3-hydroxylase enzyme
ZA981972A ZA981972B (en) 1997-03-11 1998-03-09 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives
NO994386A NO994386L (no) 1997-03-11 1999-09-10 2-substituerte benzoylcykloalkyl-1-karboksylsyrederivater

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9705031.4A GB9705031D0 (en) 1997-03-11 1997-03-11 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives

Publications (1)

Publication Number Publication Date
GB9705031D0 true GB9705031D0 (en) 1997-04-30

Family

ID=10809053

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9705031.4A Pending GB9705031D0 (en) 1997-03-11 1997-03-11 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives

Country Status (15)

Country Link
EP (1) EP0973720A1 (fr)
JP (1) JP2001514634A (fr)
KR (1) KR20000076096A (fr)
CN (1) CN1252049A (fr)
AU (1) AU6497998A (fr)
CA (1) CA2283184A1 (fr)
EA (1) EA199900809A1 (fr)
GB (1) GB9705031D0 (fr)
HU (1) HUP0001023A3 (fr)
IL (1) IL131676A0 (fr)
NO (1) NO994386L (fr)
PL (1) PL335601A1 (fr)
TW (1) TW407146B (fr)
WO (1) WO1998040344A1 (fr)
ZA (1) ZA981972B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1424333A1 (fr) * 2002-11-28 2004-06-02 Newron Pharmaceuticals S.p.A. Dérivés d'acide halothénoyl-cyclopropane-1-carboxylique
EP1475088A1 (fr) * 2003-05-05 2004-11-10 Newron Pharmaceuticals S.p.A. Inhibiteurs de la kynurenine-3-hydroxylase pour le traitement des désordres locomoteurs induits par la L-DOPA, dyskinésies, accoutumance aux médicaments, douleurs et cataract
EP1475385A1 (fr) * 2003-05-05 2004-11-10 Newron Pharmaceuticals S.p.A. Derivés de glycoside d'acide carboxylique de 2-(3,4-dichlorobenzoyl)-cyclopropane
SG11201406311UA (en) * 2012-04-05 2014-11-27 Chdi Foundation Inc Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
CN103373911B (zh) * 2012-04-27 2016-12-14 中国科学院上海有机化学研究所 单氟代环丙烷类化合物及其制备方法和应用
CN104119246A (zh) * 2013-04-26 2014-10-29 中国科学院上海有机化学研究所 环丙烷衍生物及其制备方法和应用
JP2016536350A (ja) 2013-09-26 2016-11-24 シーエイチディーアイ ファウンデーション，インコーポレーテッド キヌレニン−３−モノオキシゲナーゼ阻害薬、医薬組成物、及びこれらの使用方法
JP6449893B2 (ja) * 2013-09-26 2019-01-09 シーエイチディーアイ ファウンデーション，インコーポレーテッド キヌレニン−３−モノオキシゲナーゼ阻害薬、医薬組成物、及びこれらの使用方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3655667A (en) * 1968-04-04 1972-04-11 Smith Kline French Lab 1-(2-benzoylcyclopropylmethyl)-4-phenylpiperazines

Also Published As

Publication number Publication date
NO994386D0 (no) 1999-09-10
HUP0001023A3 (en) 2001-03-28
EA199900809A1 (ru) 2000-08-28
EP0973720A1 (fr) 2000-01-26
HUP0001023A2 (hu) 2000-09-28
IL131676A0 (en) 2001-03-19
WO1998040344A1 (fr) 1998-09-17
TW407146B (en) 2000-10-01
NO994386L (no) 1999-11-02
KR20000076096A (ko) 2000-12-26
JP2001514634A (ja) 2001-09-11
CA2283184A1 (fr) 1998-09-17
AU6497998A (en) 1998-09-29
PL335601A1 (en) 2000-05-08
ZA981972B (en) 1998-09-09
CN1252049A (zh) 2000-05-03

Similar Documents

Publication Publication Date Title
PL334997A1 (en) Derivatives or arylosulphonyl-hydroxamic acid
HU9801044D0 (en) Sulfonyl-amino-carboxylic acid derivatives
IL139470A0 (en) Oxyiminoalkanoic acid derivatives
HUP0003881A3 (en) Amidocarboxylic acid derivatives
EG24140A (en) New 3-aryl-2-hydroxypropionic acid derivative
HK1064670A1 (en) Pyridine-3-carboxylic acid derivatives
EG24081A (en) 4-Substituted-9-deoxo-9a-aza-9a-homerythromycin derivatives
IL140358A0 (en) Aminomethylarboxylic acid derivatives
ATE248812T1 (de) Arylsulfonylhydroxamsäurederivate
DK1003720T3 (da) Aryloxyarylsulfonylaminohydroxamsyrederivater
PL334847A1 (en) Substituted 3-heterocyclyl-benzoyl derivatives
GB9702194D0 (en) Sulphonide derivatives
PL344682A1 (en) New 3-aryl-2-hydroxypropionic acid derivative iii
HUP0000937A3 (en) New fatty acid derivatives
AP9901457A0 (en) Novel dihydroxyexanoic acid derivatives
AU1559199A (en) Isothiazolcarboxylic acid derivatives
HU9801072D0 (en) Substituted 6- and 7-amino-tetrahydro-isoquinoline-carboxylic acid derivatives
EP0774965A4 (fr) Derives de l'acide phenoxyphenylacetique
ZA981972B (en) 2-substituted benzoyl-cycloalkyl-1-carboxylic acid derivatives
GB9715821D0 (en) Amidino-camptothecin derivatives
GB2321457B (en) 5-Aroylnaphthalene derivatives
ZA9510888B (en) 3-aryl-tetronic acid derivatives
GB9701628D0 (en) Imino-aza-anthracyclinone derivatives
IL135639A0 (en) Novel methylenebisphosphonic acid derivatives
ZA95301B (en) Furazancarboxylic acid derivatives