GB963998A - Improvements in or relating to combating worm infections and pharmaceutical preparations therefor - Google Patents

Improvements in or relating to combating worm infections and pharmaceutical preparations therefor

Info

Publication number
GB963998A
GB963998A GB2690660A GB2690660A GB963998A GB 963998 A GB963998 A GB 963998A GB 2690660 A GB2690660 A GB 2690660A GB 2690660 A GB2690660 A GB 2690660A GB 963998 A GB963998 A GB 963998A
Authority
GB
United Kingdom
Prior art keywords
phenazine
cyano
alkyl
carboxymethylthio
dihydrophenazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2690660A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Philips Gloeilampenfabrieken NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Gloeilampenfabrieken NV filed Critical Philips Gloeilampenfabrieken NV
Publication of GB963998A publication Critical patent/GB963998A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/46Phenazines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A preparation for combating worms in domestic animals or humans comprises one or more phenazines of general formula <FORM:0963998/A5-A6/1> being a derivative of phenazine or N,N-dihydrophenazine or a monobenzhomologue of such compound, or an acid addition salt of such compound or being homologue, in which formula X and/or Y are hydrogen, 1 to 6 C alkyl, a halogen substituted or unsubstituted phenyl or an oxygen atom; R is hydrogen (except where n and m both have the value O), halogen, cyano, nitro, carboxymethylthio, 1 to 6 C alkyl and n and m are 0 or 1; mixed with, or dissolved or dispersed in an inert, non-toxic, solid or liquid pharmaceutical carrier. Typical salts are the oxalate, citrate and dihydrochloride. Typical compounds are the cyano-5-alkyl-N,N1-dihydro - phenazines, 1 - chloro - phenazine, 1,2 - benzo - phenazine, 2 - methyl - phenazine, 2 - carboxymethylthio - phenazine, 1 - nitro - phenazine, phenazine - 5 - oxide, 2 - chlorophenazine - 5 - oxide, 2 - chloro - phenazine - 5,10-dioxide, N,N1 - dihydro - 2,3 - benzo - phenazine and 2 - cyano - 10 - methyl - N,N1 - dihydrophenazine. The compounds may be put up in the form of tablets, dragees, powders, capsules, granules, aqueous suspensions for injection containing wetting agents and aerosols. The oral preparations may be added to the food or drinking water.
GB2690660A 1959-08-06 1960-08-03 Improvements in or relating to combating worm infections and pharmaceutical preparations therefor Expired GB963998A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL242088 1959-08-06

Publications (1)

Publication Number Publication Date
GB963998A true GB963998A (en) 1964-07-15

Family

ID=19751863

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2690660A Expired GB963998A (en) 1959-08-06 1960-08-03 Improvements in or relating to combating worm infections and pharmaceutical preparations therefor

Country Status (1)

Country Link
GB (1) GB963998A (en)

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