GB946660A - New 18-unsubstituted 20-hydroxy-pregnanes - Google Patents
New 18-unsubstituted 20-hydroxy-pregnanesInfo
- Publication number
- GB946660A GB946660A GB3021863A GB3021863A GB946660A GB 946660 A GB946660 A GB 946660A GB 3021863 A GB3021863 A GB 3021863A GB 3021863 A GB3021863 A GB 3021863A GB 946660 A GB946660 A GB 946660A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxy
- pregnan
- compound
- prepared
- pregnane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YPEARZUTWVZHIZ-SRJHXTLLSA-N 1-[(8r,9s,10s,13s,14s,17s)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]ethanol Chemical class C1CC2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(O)C)[C@@]1(C)CC2 YPEARZUTWVZHIZ-SRJHXTLLSA-N 0.000 title 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 125000004043 oxo group Chemical group O=* 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- NFVCQZNBRFPYOP-WDDOJFKXSA-N 1-[(3r,5r,8s,9s,10s,11r,13s,14s,17s)-3,11-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]ethanone Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)C)[C@@]2(C)C[C@H]1O NFVCQZNBRFPYOP-WDDOJFKXSA-N 0.000 abstract 1
- JWMFYGXQPXQEEM-NUNROCCHSA-N 5β-pregnane Chemical class C([C@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](CC)[C@@]2(C)CC1 JWMFYGXQPXQEEM-NUNROCCHSA-N 0.000 abstract 1
- DSAFNTCDJNKWMC-XALJHJQMSA-N [(3R,5R,8S,9S,10S,11R,13S,14S,17S)-17-acetyl-11-(2,2-dimethylpropanoyloxy)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] 2,2-dimethylpropanoate Chemical compound C(C(C)(C)C)(=O)O[C@H]1C[C@H]2CC[C@H]3[C@@H]4CC[C@H](C(C)=O)[C@]4(C[C@H]([C@@H]3[C@]2(CC1)C)OC(C(C)(C)C)=O)C DSAFNTCDJNKWMC-XALJHJQMSA-N 0.000 abstract 1
- WKXFITALZPRZNJ-MMLWLGQSSA-N [(3R,5R,8S,9S,10S,11R,13S,14S,17S)-17-acetyl-11-(cyclohexanecarbonyloxy)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] cyclohexanecarboxylate Chemical compound C(C1CCCCC1)(=O)O[C@H]1C[C@H]2CC[C@H]3[C@@H]4CC[C@H](C(C)=O)[C@]4(C[C@H]([C@@H]3[C@]2(CC1)C)OC(C1CCCCC1)=O)C WKXFITALZPRZNJ-MMLWLGQSSA-N 0.000 abstract 1
- HYQTUNRHCJOGEO-STIDOHQZSA-N [(3R,5R,8S,9S,10S,11S,13S,14S,17S)-17-acetyl-11-acetyloxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate Chemical compound C(C)(=O)O[C@H]1C[C@H]2CC[C@H]3[C@@H]4CC[C@H](C(C)=O)[C@]4(C[C@@H]([C@@H]3[C@]2(CC1)C)OC(C)=O)C HYQTUNRHCJOGEO-STIDOHQZSA-N 0.000 abstract 1
- YTDLAIOQXZNXPM-MMLWLGQSSA-N [(3r,5r,8s,9s,10s,11r,13s,14s,17s)-17-acetyl-11-benzoyloxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-3-yl] benzoate Chemical compound O([C@H]1[C@@H]2[C@@]3(C)CC[C@H](C[C@H]3CC[C@H]2[C@@H]2CC[C@@H]([C@]2(C1)C)C(=O)C)OC(=O)C=1C=CC=CC=1)C(=O)C1=CC=CC=C1 YTDLAIOQXZNXPM-MMLWLGQSSA-N 0.000 abstract 1
- NNMJHVBZUSISMC-BORMIPFCSA-N [(3r,5r,8s,9s,10s,13s,14s,17s)-17-acetyl-10,13-dimethyl-11-oxo-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl] acetate Chemical compound C1C(=O)[C@@H]2[C@@]3(C)CC[C@@H](OC(=O)C)C[C@H]3CC[C@H]2[C@@H]2CC[C@H](C(C)=O)[C@]21C NNMJHVBZUSISMC-BORMIPFCSA-N 0.000 abstract 1
- 230000021736 acetylation Effects 0.000 abstract 1
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000005907 ketalization reaction Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH6947559A CH383953A (de) | 1959-02-12 | 1959-02-12 | Verfahren zur Herstellung von 18,20-Oxido-steroiden |
| CH7244359 | 1959-04-23 | ||
| CH7375459 | 1959-05-29 | ||
| CH7526059 | 1959-07-03 | ||
| CH8178059A CH407111A (de) | 1959-12-11 | 1959-12-11 | Verfahren zur Herstellung von neuen Hydroxyaldehyden der Pregnanreihe |
| CH8223359 | 1959-12-22 | ||
| CH8223159 | 1959-12-22 | ||
| CH8223459 | 1959-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB946660A true GB946660A (en) | 1964-01-15 |
Family
ID=31721976
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB510960A Expired GB946656A (en) | 1959-02-12 | 1960-02-12 | 18:20-oxido-steroids and process for their manufacture |
| GB3021863A Expired GB946660A (en) | 1959-02-12 | 1960-02-12 | New 18-unsubstituted 20-hydroxy-pregnanes |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB510960A Expired GB946656A (en) | 1959-02-12 | 1960-02-12 | 18:20-oxido-steroids and process for their manufacture |
Country Status (2)
| Country | Link |
|---|---|
| GB (2) | GB946656A (enrdf_load_stackoverflow) |
| SE (1) | SE305207B (enrdf_load_stackoverflow) |
-
1960
- 1960-02-12 GB GB510960A patent/GB946656A/en not_active Expired
- 1960-02-12 SE SE146060A patent/SE305207B/xx unknown
- 1960-02-12 GB GB3021863A patent/GB946660A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SE305207B (enrdf_load_stackoverflow) | 1968-10-21 |
| GB946656A (en) | 1964-01-15 |
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