GB939468A - Improvements in or relating to a sulphonamide - Google Patents
Improvements in or relating to a sulphonamideInfo
- Publication number
- GB939468A GB939468A GB37295/61A GB3729561A GB939468A GB 939468 A GB939468 A GB 939468A GB 37295/61 A GB37295/61 A GB 37295/61A GB 3729561 A GB3729561 A GB 3729561A GB 939468 A GB939468 A GB 939468A
- Authority
- GB
- United Kingdom
- Prior art keywords
- chloro
- salts
- sulphonamide
- relating
- saliuretic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 title 1
- 229940124530 sulfonamide Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 2
- UAHWWAIVYPJROV-UHFFFAOYSA-N 2,6-dimethylpiperidin-1-amine Chemical compound CC1CCCC(C)N1N UAHWWAIVYPJROV-UHFFFAOYSA-N 0.000 abstract 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 1
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229940050390 benzoate Drugs 0.000 abstract 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- NZNMSOFKMUBTKW-UHFFFAOYSA-N cyclohexanecarboxylic acid Chemical compound OC(=O)C1CCCCC1 NZNMSOFKMUBTKW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000007791 liquid phase Substances 0.000 abstract 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1
- -1 methansulphonate Chemical compound 0.000 abstract 1
- 150000007530 organic bases Chemical group 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000000894 saliuretic effect Effects 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- 229940095064 tartrate Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/28—Nitrogen atoms
- C07D295/32—Nitrogen atoms acylated with carboxylic or carbonic acids, or their nitrogen or sulfur analogues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/50—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
- C07D245/02—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/02—1,2-Oxazines; Hydrogenated 1,2-oxazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1254760A CH396905A (de) | 1960-11-09 | 1960-11-09 | Verfahren zur Herstellung von neuen Hydrazin-Derivaten |
| CH1354460 | 1960-12-02 | ||
| CH654761A CH418335A (de) | 1960-11-09 | 1961-06-06 | Verfahren zur Herstellung von neuen Hydrazin-Derivaten |
| CH1047461 | 1961-09-11 | ||
| CH1518864A CH412892A (de) | 1960-11-09 | 1961-09-11 | Verfahren zur Herstellung von neuen Hydrazin-Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB939468A true GB939468A (en) | 1963-10-16 |
Family
ID=43798563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB37295/61A Expired GB939468A (en) | 1960-11-09 | 1961-10-18 | Improvements in or relating to a sulphonamide |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US3445573A (en:Method) |
| BR (1) | BR6134007D0 (en:Method) |
| CH (2) | CH418335A (en:Method) |
| FR (1) | FR1748M (en:Method) |
| GB (1) | GB939468A (en:Method) |
| LU (1) | LU40792A1 (en:Method) |
| NL (1) | NL270803A (en:Method) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1586468A (en) * | 1976-10-29 | 1981-03-18 | Anphar Sa | Piperidine derivatives |
| EP1545519B1 (en) | 2002-08-19 | 2011-03-23 | Pfizer Inc. | Combination therapy for hyperproliferative diseases |
| US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| EP2094643B1 (en) | 2006-12-01 | 2012-02-29 | Bristol-Myers Squibb Company | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
| CN105143203A (zh) | 2013-04-17 | 2015-12-09 | 辉瑞大药厂 | 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| ES3007652T3 (en) | 2019-01-18 | 2025-03-20 | Astrazeneca Ab | 6'-[[(1s,3s)-3-[[5-(difluoromethoxy)-2-pyrimidinyl]amino]cyclopentyl]amino][1(2h),3'-bipyridin]-2-one as pcsk9 inhibitor and methods of use thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3043874A (en) * | 1960-05-09 | 1962-07-10 | Parke Davis & Co | 4-halo-3-sulfamoylbenzoic acid derivatives and methods for producing same |
| CH430711A (de) * | 1963-12-20 | 1967-02-28 | Sandoz Ag | Verfahren zur Herstellung von neuen heterocyclischen Verbindungen |
-
0
- NL NL270803D patent/NL270803A/xx unknown
-
1961
- 1961-06-06 CH CH654761A patent/CH418335A/de unknown
- 1961-09-11 CH CH1518864A patent/CH412892A/de unknown
- 1961-10-18 GB GB37295/61A patent/GB939468A/en not_active Expired
- 1961-11-07 LU LU40792A patent/LU40792A1/xx unknown
- 1961-11-08 BR BR134007/61A patent/BR6134007D0/pt unknown
-
1962
- 1962-02-06 FR FR887088A patent/FR1748M/fr not_active Expired
-
1966
- 1966-06-24 US US560062A patent/US3445573A/en not_active Expired - Lifetime
-
1967
- 1967-04-17 US US645082A patent/US3459756A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CH418335A (de) | 1966-08-15 |
| NL270803A (en:Method) | |
| BR6134007D0 (pt) | 1973-05-31 |
| FR1748M (fr) | 1963-03-25 |
| CH412892A (de) | 1966-05-15 |
| LU40792A1 (en:Method) | 1962-05-07 |
| US3459756A (en) | 1969-08-05 |
| US3445573A (en) | 1969-05-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB939468A (en) | Improvements in or relating to a sulphonamide | |
| GB1382939A (en) | Heterocyclic benzamide compounds processes for making them and compositions containing them | |
| GB970886A (en) | New pyridines and process for the manufacture thereof | |
| ES391633A1 (es) | Un procedimiento para la preparacion de una 2,2-diaril-4- piperidinobutiramida. | |
| GB1415471A (en) | Phenylethylamine derivatives | |
| GB1394504A (en) | 1,2-bis-4-phenyl-1-piperazinyl-ethane derivatives | |
| ES427433A1 (es) | Un procedimiento para preparar un compuesto quimico selec- cionado del grupo que consiste en o-tiocarbamato de nitroi- midazolil-etilo. | |
| GB1451902A (en) | Bromo dihydrolysergic acid | |
| GB1449070A (en) | Aminotetralins and use in inducing anesthesia | |
| GB889317A (en) | New phenyl-diazines and a process for their manufacture | |
| GB1277566A (en) | Quinazoline and isoquinoline bronchodilators | |
| GB1120186A (en) | Cyclohexene amino acid derivatives and process for their preparation | |
| GB1498083A (en) | Pharmaceutical preparations | |
| GB1467761A (en) | Phenoxypropylamine derivatives and preparation thereof | |
| GB1451389A (en) | Indolobenzazepines | |
| GB1245155A (en) | NOVEL 5-SUBSTITUTED-gamma-CARBOLINE DERIVATIVES AND THE SALTS THEREOF | |
| GB1073521A (en) | Indole derivatives | |
| JPS5268170A (en) | Preparation of novel methano-anthracene derivatives | |
| GB1202140A (en) | Benzodiazepine derivatives | |
| GB1212550A (en) | Benzyl alcohol derivatives | |
| GB1178090A (en) | Piperidine Derivatives | |
| ES424362A1 (es) | Un proceso para la preparacion y estabilizacion de una com-posicion oftalmica, administrable topicamente. | |
| GB1067694A (en) | A process for the preparation of 2-alkyl-4-alkylamino-6-alkoxy-s-triazines | |
| GB878284A (en) | 1-o-tolyloxyethyl-4-phenyl-piperidine | |
| GB957992A (en) | Quaternized aminoalkyl esters of 3,4,5-trimethoxybenzoic acid |