GB935406A - Novel piperazine derivatives and a process for the manufacture thereof - Google Patents
Novel piperazine derivatives and a process for the manufacture thereofInfo
- Publication number
- GB935406A GB935406A GB1527/62A GB152762A GB935406A GB 935406 A GB935406 A GB 935406A GB 1527/62 A GB1527/62 A GB 1527/62A GB 152762 A GB152762 A GB 152762A GB 935406 A GB935406 A GB 935406A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxy
- group
- alkoxy
- amino
- nitro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000004885 piperazines Chemical class 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- -1 hydroxy, nitro, amino Chemical group 0.000 abstract 3
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- KGIGUEBEKRSTEW-UHFFFAOYSA-N 2-vinylpyridine Chemical compound C=CC1=CC=CC=N1 KGIGUEBEKRSTEW-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 230000000578 anorexic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010061428 decreased appetite Diseases 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 239000007937 lozenge Substances 0.000 abstract 1
- YZTJYBJCZXZGCT-UHFFFAOYSA-N phenylpiperazine Chemical compound C1CNCCN1C1=CC=CC=C1 YZTJYBJCZXZGCT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH71361 | 1961-01-20 | ||
| CH419461 | 1961-04-10 | ||
| CH1175461 | 1961-10-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB935406A true GB935406A (en) | 1963-08-28 |
Family
ID=27172340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1527/62A Expired GB935406A (en) | 1961-01-20 | 1962-01-16 | Novel piperazine derivatives and a process for the manufacture thereof |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE612485A (enrdf_load_stackoverflow) |
| ES (1) | ES273864A1 (enrdf_load_stackoverflow) |
| FR (2) | FR1725M (enrdf_load_stackoverflow) |
| GB (1) | GB935406A (enrdf_load_stackoverflow) |
| NL (1) | NL273281A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2070687A1 (enrdf_load_stackoverflow) * | 1969-09-12 | 1971-09-17 | Hoechst Ag |
-
0
- BE BE612485D patent/BE612485A/xx unknown
- NL NL273281D patent/NL273281A/xx unknown
- FR FR1310270D patent/FR1310270A/fr not_active Expired
-
1962
- 1962-01-12 FR FR884616A patent/FR1725M/fr not_active Expired
- 1962-01-16 GB GB1527/62A patent/GB935406A/en not_active Expired
- 1962-01-19 ES ES0273864A patent/ES273864A1/es not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2070687A1 (enrdf_load_stackoverflow) * | 1969-09-12 | 1971-09-17 | Hoechst Ag |
Also Published As
| Publication number | Publication date |
|---|---|
| ES273864A1 (es) | 1962-07-16 |
| NL273281A (enrdf_load_stackoverflow) | |
| FR1310270A (enrdf_load_stackoverflow) | 1963-03-06 |
| FR1725M (fr) | 1963-03-11 |
| BE612485A (enrdf_load_stackoverflow) |
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