GB933702A - Process for the production of n-methanesulfonic acid derivatives of kanamycin - Google Patents
Process for the production of n-methanesulfonic acid derivatives of kanamycinInfo
- Publication number
- GB933702A GB933702A GB39876/59A GB3987659A GB933702A GB 933702 A GB933702 A GB 933702A GB 39876/59 A GB39876/59 A GB 39876/59A GB 3987659 A GB3987659 A GB 3987659A GB 933702 A GB933702 A GB 933702A
- Authority
- GB
- United Kingdom
- Prior art keywords
- kanamycin
- methane
- sodium
- sulphonate
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930027917 kanamycin Natural products 0.000 title 1
- 229960000318 kanamycin Drugs 0.000 title 1
- 229930182823 kanamycin A Natural products 0.000 title 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 5
- 230000003115 biocidal effect Effects 0.000 abstract 4
- BITYAPCSNKJESK-UHFFFAOYSA-N potassiosodium Chemical compound [Na].[K] BITYAPCSNKJESK-UHFFFAOYSA-N 0.000 abstract 3
- 239000011734 sodium Substances 0.000 abstract 3
- 229910052708 sodium Inorganic materials 0.000 abstract 3
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 2
- RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical compound O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 2
- 229930193140 Neomycin Chemical class 0.000 abstract 1
- 229930040373 Paraformaldehyde Natural products 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- JXRVKYBCWUJJBP-UHFFFAOYSA-L calcium;hydrogen sulfate Chemical compound [Ca+2].OS([O-])(=O)=O.OS([O-])(=O)=O JXRVKYBCWUJJBP-UHFFFAOYSA-L 0.000 abstract 1
- FOQKTXAEOGULKQ-UHFFFAOYSA-L calcium;hydroxymethanesulfonate Chemical compound [Ca+2].OCS([O-])(=O)=O.OCS([O-])(=O)=O FOQKTXAEOGULKQ-UHFFFAOYSA-L 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical class O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 229960004927 neomycin Drugs 0.000 abstract 1
- 229920002866 paraformaldehyde Polymers 0.000 abstract 1
- 239000004291 sulphur dioxide Substances 0.000 abstract 1
- 235000010269 sulphur dioxide Nutrition 0.000 abstract 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3554558 | 1958-12-12 | ||
| JP962259 | 1959-03-28 | ||
| JP1595559 | 1959-05-21 | ||
| JP3384159 | 1959-10-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB933702A true GB933702A (en) | 1963-08-08 |
Family
ID=27455216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB39876/59A Expired GB933702A (en) | 1958-12-12 | 1959-11-24 | Process for the production of n-methanesulfonic acid derivatives of kanamycin |
Country Status (4)
| Country | Link |
|---|---|
| CH (1) | CH421384A (enrdf_load_html_response) |
| DK (1) | DK118502B (enrdf_load_html_response) |
| FR (1) | FR435M (enrdf_load_html_response) |
| GB (1) | GB933702A (enrdf_load_html_response) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091202A (en) * | 1975-09-25 | 1978-05-23 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | N-methanesulfonic acid derivatives of 3',4'-dideoxykanamycin B |
-
1959
- 1959-11-24 GB GB39876/59A patent/GB933702A/en not_active Expired
- 1959-12-11 DK DK449359AA patent/DK118502B/da unknown
- 1959-12-11 CH CH8174559A patent/CH421384A/de unknown
-
1960
- 1960-08-22 FR FR836408A patent/FR435M/fr active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091202A (en) * | 1975-09-25 | 1978-05-23 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | N-methanesulfonic acid derivatives of 3',4'-dideoxykanamycin B |
Also Published As
| Publication number | Publication date |
|---|---|
| DK118502B (da) | 1970-08-31 |
| FR435M (enrdf_load_html_response) | 1961-04-24 |
| CH421384A (de) | 1966-09-30 |
| DE1418452A1 (de) | 1968-10-24 |
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