GB933668A - Skin barrier compositions - Google Patents

Skin barrier compositions

Info

Publication number
GB933668A
GB933668A GB36592/61A GB3659261A GB933668A GB 933668 A GB933668 A GB 933668A GB 36592/61 A GB36592/61 A GB 36592/61A GB 3659261 A GB3659261 A GB 3659261A GB 933668 A GB933668 A GB 933668A
Authority
GB
United Kingdom
Prior art keywords
chloride
aluminium
halides
water
ethyl alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB36592/61A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DEPUTY MINISTER OF MINISTE
Original Assignee
DEPUTY MINISTER OF MINISTE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DEPUTY MINISTER OF MINISTE filed Critical DEPUTY MINISTER OF MINISTE
Publication of GB933668A publication Critical patent/GB933668A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8129—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers or esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers, e.g. polyvinylmethylether
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K13/00—Use of mixtures of ingredients not covered by one single of the preceding main groups, each of these compounds being essential
    • C08K13/02—Organic and inorganic ingredients
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L29/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
    • C08L29/02—Homopolymers or copolymers of unsaturated alcohols
    • C08L29/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants

Abstract

Skin barrier compositions of viscous liquid form comprise a water-soluble polyvinyl alcohol with a K index of 30 to 120 and an acetyl group content of below 40%, a plasticizer therefor, a non-ionic wetting agent, water and a preserving agent such as one or more halides or hydroxy halides of a metal of Group II, III, IV or VIII of the Periodic Table. Specified plasticizers are ethylene glycol, triethylene glycol and glycerine. Specified non-ionic wetting agents are condensates of ethylene oxide with long chain alcohols, acids and alkyl phenols, particularly isooctyl phenol. Specified metal halides are magnesium chloride, calcium chloride, zinc chloride, ferric chloride, aluminium chloride and aluminium hydroxy chloride. The compositions may also comprise means for improving adherence to the skin, e.g. gelatin; anaesthetic substances, e.g. benzocaine, novocaine and benzyl alcohol; bacteriostatic substances, e.g. pyrogallol, thymol iodide, 7-iodo-8-hydroxyquinolinic acid, 2,4-m-dichloro xylenol, benzyl benzoate, b -naphthol benzoate, and azo and acridine dyestuffs; and water-soluble volatile organic liquids, e.g. ethyl alcohol. Examples describe aqueous compositions comprising polyvinyl alcohol, glycerine, isooctylphenol polyethoxylate and (1) aluminium chloride; (2) aluminium chloride and ethyl alcohol; (3 and 4) aluminium chloride, ethyl alcohol and gelatin; and (5) aluminium hydroxy chloride with (a) magnesium chloride, (b) calcium chloride and gelatin, and (c) zinc chloride and gelatin.ALSO:Skin barrier compositions of viscous liquid form comprise a water-soluble polyvinyl alcohol with a K index of 30 to 120 and an acetyl group content of below 40%, a plasticizer therefor, a non-ionic wetting-agent, water and a preserving agent such as one or more halides or hydroxy-halides of a metal of Group II, III, IV or VIII of the Periodic Table. Specified plasticizers are ethylene glycol, triethylene glycol and glycerine. Specified non-ionic wetting agents are condensates of ethylene oxide with long-chain alcohols, acids and alkylphenols, particularly iso-octyl phenol. Specified metal halides are magnesium chloride, calcium chloride, zinc chloride, ferric chloride, aluminium chloride and aluminium hydroxychloride. The compositions may also comprise means for improving adherence to the skin, e.g. gelatine; anaesthetic substances, e.g. benzocaine, novocaine and benzyl alcohol; bacteriostatic substances, e.g. pyrogallol, thymol iodide, 7-iodo-8-hydroxyquinolinic acid, 2,4-m-dichloro xylenol, benzyl benzoate, b -naphthol benzoate, and azo and acridine dyestuffs; and water-soluble volatile organic liquids, e.g. ethyl alcohol. Examples describe aqueous compositions comprising polyvinyl alcohol, glycerine, iso-octyl phenol polyethoxylate and (1) aluminium chloride; (2) aluminium chloride and ethyl alcohol; (3 and 4) aluminium chloride, ethyl alcohol and gelatine; and (5) aluminium hydroxychloride with (a) magnesium chloride, (b) calcium chloride and gelatine, and (c) zinc chloride and gelatine.
GB36592/61A 1960-10-14 1961-10-12 Skin barrier compositions Expired GB933668A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RO4387960 1960-10-14

Publications (1)

Publication Number Publication Date
GB933668A true GB933668A (en) 1963-08-08

Family

ID=20086367

Family Applications (1)

Application Number Title Priority Date Filing Date
GB36592/61A Expired GB933668A (en) 1960-10-14 1961-10-12 Skin barrier compositions

Country Status (3)

Country Link
DE (1) DE1249458B (en)
FR (1) FR2261M (en)
GB (1) GB933668A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4438139A (en) 1979-08-14 1984-03-20 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estrogens
US4460562A (en) * 1982-01-06 1984-07-17 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing propranolol
US4466953A (en) * 1979-08-14 1984-08-21 Key Pharmaceuticals, Inc. Polymeric diffusion matrix
US4585797A (en) * 1981-04-13 1986-04-29 Seton Company Cosmetic and pharmaceutical sheet material containing polypeptides
US4591501A (en) * 1981-04-13 1986-05-27 Seton Company Cosmetic and pharmaceutical sheet material containing polypeptides
US5888494A (en) * 1996-03-12 1999-03-30 Adolor Corporation Film-forming compositions of antihyperalgesic opiates and method of treating hyperalgesic and pruritic conditions therewith
WO2003075970A1 (en) * 2002-03-13 2003-09-18 Schoetta Miroslav Protective film on the basis of a modified polymeric compound
EP1408902A2 (en) * 2001-06-22 2004-04-21 Millard Marsden Mershon Compositions and methods for reducing blood and fluid loss from open wounds
EP1362581B2 (en) † 2002-05-17 2015-02-11 Pureific Corp. Cosmetic foundation comprising a combination of antiperspirant and antimicrobial agents
WO2024067711A1 (en) * 2022-09-27 2024-04-04 中新巨成医学科技有限公司 Biological simulation material, and preparation method therefor and use thereof

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2566270A1 (en) * 1984-06-25 1985-12-27 Ausonia Farma Srl Pharmaceutical dosage forms in gel form, for the topical application of active principles
DE3443737A1 (en) * 1984-11-30 1986-06-05 Giulini Chemie Gmbh, 6700 Ludwigshafen LESS Greasy and little occlusive masses for the production of skin care products and ointments

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4492685A (en) * 1979-08-14 1985-01-08 Key Pharmaceuticals, Inc. Protective skin matrix
US4438139A (en) 1979-08-14 1984-03-20 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estrogens
US4466953A (en) * 1979-08-14 1984-08-21 Key Pharmaceuticals, Inc. Polymeric diffusion matrix
US4470962A (en) * 1979-08-14 1984-09-11 Key Pharmaceuticals, Inc. Polymeric diffusion matrix
US4591501A (en) * 1981-04-13 1986-05-27 Seton Company Cosmetic and pharmaceutical sheet material containing polypeptides
US4585797A (en) * 1981-04-13 1986-04-29 Seton Company Cosmetic and pharmaceutical sheet material containing polypeptides
US4460562A (en) * 1982-01-06 1984-07-17 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing propranolol
US5888494A (en) * 1996-03-12 1999-03-30 Adolor Corporation Film-forming compositions of antihyperalgesic opiates and method of treating hyperalgesic and pruritic conditions therewith
EP1408902A2 (en) * 2001-06-22 2004-04-21 Millard Marsden Mershon Compositions and methods for reducing blood and fluid loss from open wounds
EP1408902A4 (en) * 2001-06-22 2008-02-13 Millard Marsden Mershon Compositions and methods for reducing blood and fluid loss from open wounds
WO2003075970A1 (en) * 2002-03-13 2003-09-18 Schoetta Miroslav Protective film on the basis of a modified polymeric compound
EP1362581B2 (en) † 2002-05-17 2015-02-11 Pureific Corp. Cosmetic foundation comprising a combination of antiperspirant and antimicrobial agents
WO2024067711A1 (en) * 2022-09-27 2024-04-04 中新巨成医学科技有限公司 Biological simulation material, and preparation method therefor and use thereof

Also Published As

Publication number Publication date
DE1249458B (en) 1967-09-07
FR2261M (en) 1964-01-13

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