GB9319732D0 - Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety - Google Patents
Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxietyInfo
- Publication number
- GB9319732D0 GB9319732D0 GB939319732A GB9319732A GB9319732D0 GB 9319732 D0 GB9319732 D0 GB 9319732D0 GB 939319732 A GB939319732 A GB 939319732A GB 9319732 A GB9319732 A GB 9319732A GB 9319732 D0 GB9319732 D0 GB 9319732D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyrrolidineacetamide
- anxiety
- oxo
- alpha
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000019901 Anxiety disease Diseases 0.000 title abstract 2
- 230000036506 anxiety Effects 0.000 title abstract 2
- HPHUVLMMVZITSG-LURJTMIESA-N levetiracetam Chemical compound CC[C@@H](C(N)=O)N1CCCC1=O HPHUVLMMVZITSG-LURJTMIESA-N 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939319732A GB9319732D0 (en) | 1993-09-24 | 1993-09-24 | Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety |
| CA002132509A CA2132509A1 (en) | 1993-09-24 | 1994-09-20 | Treatment of anxiety with the aid of (s)-(-)-.alpha.- ethyl-2-oxo-1-pyrrolidineacetamide |
| HU9402704A HU217124B (hu) | 1993-09-24 | 1994-09-20 | Eljárás (S)-(-)-alfa-etil-2-oxo-1-pirrolidin-acetamid-tartalmú, szorongás oldására alkalmas gyógyászati készítmények előállítására |
| US08/309,186 US5447952A (en) | 1993-09-24 | 1994-09-20 | Treatment of anxiety with the aid of (S)-(-)-α-ethyl-2-oxo-1-pyrrolidineacetamide |
| NZ264506A NZ264506A (en) | 1993-09-24 | 1994-09-21 | Use of (s)-(-)-alpha-ethyl-2-oxo-1-pyrrolidine acetamide in anxiolytic treatment |
| SG9502212A SG86284A1 (en) | 1993-09-24 | 1994-09-21 | Use of (s)-(-)-alpha-ethyl-2-oxo-1- pyrrolidineacetamide for the manufacture of medicaments for the treatment of anxiety |
| ES94870152T ES2145818T3 (es) | 1993-09-24 | 1994-09-21 | Utilizacion de la (s)-(-)-alfa-etil-2-oxo-1-pirrolidin-acetamida para la preparacion de medicamentos destinados al tratamiento de la ansiedad. |
| AT94870152T ATE191849T1 (de) | 1993-09-24 | 1994-09-21 | Verwendung von (s)-(-)-alpha-ethyl-2-oxo-1- pyrrolidinacetamid zur herstellung eines medikaments zur behandlung von angst |
| EP94870152A EP0645139B1 (fr) | 1993-09-24 | 1994-09-21 | Utilisation du (S)-(-)-alpha-éthyl-2-oxo-1-pyrrolidineacétamide pour la préparation de médicaments destinés au traitement de l'anxiété |
| TW083108691A TW283642B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-09-24 | 1994-09-21 | |
| DE69424009T DE69424009T2 (de) | 1993-09-24 | 1994-09-21 | Verwendung von (S)-(-)-alpha-ethyl-2-oxo-1-pyrrolidinacetamid zur Herstellung eines Medikaments zur Behandlung von Angst |
| NO943521A NO943521L (no) | 1993-09-24 | 1994-09-22 | Anvendelse av et pyrrolidinacetamidderivat for fremstilling av et terapeutikum |
| JP22833194A JP3688735B2 (ja) | 1993-09-24 | 1994-09-22 | （Ｓ）−（−）−α−エチル−２−オキソ−１−ピロリジ ンアセトアミドを用いる不安の治療法 |
| AU74169/94A AU672334B2 (en) | 1993-09-24 | 1994-09-22 | Treatment of anxiety with the aid of (S)-(-)-alpha-ethyl-2- oxo-1-pyrrolidineacetamide |
| KR1019940024170A KR950007848A (ko) | 1993-09-24 | 1994-09-23 | (S)-(-)-α-에틸-2-옥소-1-피롤리딘아세트아미드를 사용한 불안치료방법 |
| RU94034109A RU2142274C1 (ru) | 1993-09-24 | 1994-09-23 | Агент для лечения состояния тревоги |
| ZA947444A ZA947444B (en) | 1993-09-24 | 1994-09-23 | Treatment of anxiety with the aid of (S)-(-)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939319732A GB9319732D0 (en) | 1993-09-24 | 1993-09-24 | Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB9319732D0 true GB9319732D0 (en) | 1993-11-10 |
Family
ID=10742476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB939319732A Pending GB9319732D0 (en) | 1993-09-24 | 1993-09-24 | Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety |
Country Status (17)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5525347A (en) * | 1995-01-31 | 1996-06-11 | Medical University Of South Carolina | Composition and methods for treating performance anxiety |
| ATE361751T1 (de) | 1999-12-01 | 2007-06-15 | Ucb Sa | Ein pyrrolidinacetatderivat zur behandlung von chronischem oder neuropathischem schmerz |
| GB0004297D0 (en) | 2000-02-23 | 2000-04-12 | Ucb Sa | 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses |
| WO2007086891A1 (en) * | 2006-01-24 | 2007-08-02 | Teva Pharmaceutical Industries Ltd. | Levetiracetam formulations and methods for their manufacture |
| EP1998774A1 (en) * | 2006-03-15 | 2008-12-10 | Actelion Pharmaceuticals Ltd. | Tetrahydroisoquinoline derivatives to enhance memory function |
| WO2008021666A2 (en) * | 2006-08-18 | 2008-02-21 | Morton Grove Pharmaceuticals, Inc. | Stable liquid levetiracetam compositions and methods |
| KR20100041805A (ko) * | 2007-07-03 | 2010-04-22 | 액테리온 파마슈티칼 리미티드 | 3-아자-비시클로[3.3.0]옥탄 화합물 |
| CA2693820A1 (en) * | 2007-07-27 | 2009-02-05 | Actelion Pharmaceuticals Ltd | 2-aza-bicyclo[3.3.0]octane derivatives |
| AU2009303834B2 (en) * | 2008-10-16 | 2016-08-11 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| US8191547B2 (en) * | 2008-10-23 | 2012-06-05 | S-2Tech Llc | Portable solar-heating system having an inflatable solar collector |
| US20100159009A1 (en) * | 2008-12-24 | 2010-06-24 | Zhongshui Yu | Controlled-release formulations |
| US20100172979A1 (en) * | 2008-12-24 | 2010-07-08 | Zhongshui Yu | Controlled-release formulations |
| EA202092673A3 (ru) * | 2010-02-09 | 2021-05-31 | Дзе Джонс Хопкинс Юниверсити | Способы и композиции для улучшения когнитивной функции |
| WO2012109491A1 (en) * | 2011-02-09 | 2012-08-16 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| CA2891122C (en) | 2012-11-14 | 2021-07-20 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| US10806717B2 (en) | 2013-03-15 | 2020-10-20 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| WO2014144801A1 (en) | 2013-03-15 | 2014-09-18 | Agenebio Inc. | Methods and compositions for improving cognitive function |
| NZ738682A (en) | 2015-05-22 | 2022-01-28 | Agenebio Inc | Extended release pharmaceutical compositions of levetiracetam |
| CA3117350A1 (en) * | 2018-12-04 | 2020-06-11 | Metys Pharmaceuticals AG | Synergistic compositions comprising (r)-2-(2-oxopyrrolidin-1-yl)butanamide and (s)-2-(2-oxopyrrolidin-1-yl)butanamide in a non-racemic ratio |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1414845A1 (ru) * | 1984-03-23 | 1988-08-07 | Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе | 1-Тиокарбамоилметилпирролидин-2-тион,обладающий ноотропной активностью, и способ его получени |
| GB8412357D0 (en) * | 1984-05-15 | 1984-06-20 | Ucb Sa | Pharmaceutical composition |
| SU1320707A1 (ru) * | 1985-01-24 | 1987-06-30 | Ивано-Франковский Институт Нефти И Газа | Способ определени износостойкости материалов ма тниковым склерометром |
| GB8827389D0 (en) | 1988-11-23 | 1988-12-29 | Ucb Sa | Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
| EP0408782A1 (en) * | 1989-07-18 | 1991-01-23 | Nauchnoissledovatelski Chimikopharmatzevtichen Institut | Antihypoxic agent |
| CA2048003A1 (en) * | 1990-08-21 | 1992-02-22 | Serge Burner | Tricyclic pyridone derivatives |
-
1993
- 1993-09-24 GB GB939319732A patent/GB9319732D0/en active Pending
-
1994
- 1994-09-20 US US08/309,186 patent/US5447952A/en not_active Expired - Lifetime
- 1994-09-20 HU HU9402704A patent/HU217124B/hu not_active IP Right Cessation
- 1994-09-20 CA CA002132509A patent/CA2132509A1/en not_active Abandoned
- 1994-09-21 NZ NZ264506A patent/NZ264506A/en unknown
- 1994-09-21 ES ES94870152T patent/ES2145818T3/es not_active Expired - Lifetime
- 1994-09-21 SG SG9502212A patent/SG86284A1/en unknown
- 1994-09-21 AT AT94870152T patent/ATE191849T1/de not_active IP Right Cessation
- 1994-09-21 EP EP94870152A patent/EP0645139B1/fr not_active Expired - Lifetime
- 1994-09-21 TW TW083108691A patent/TW283642B/zh active
- 1994-09-21 DE DE69424009T patent/DE69424009T2/de not_active Expired - Lifetime
- 1994-09-22 JP JP22833194A patent/JP3688735B2/ja not_active Expired - Fee Related
- 1994-09-22 NO NO943521A patent/NO943521L/no unknown
- 1994-09-22 AU AU74169/94A patent/AU672334B2/en not_active Ceased
- 1994-09-23 RU RU94034109A patent/RU2142274C1/ru active
- 1994-09-23 KR KR1019940024170A patent/KR950007848A/ko not_active Abandoned
- 1994-09-23 ZA ZA947444A patent/ZA947444B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU217124B (hu) | 1999-11-29 |
| HUT68299A (en) | 1995-06-28 |
| ZA947444B (en) | 1995-05-11 |
| NO943521L (no) | 1995-03-27 |
| DE69424009D1 (de) | 2000-05-25 |
| AU7416994A (en) | 1995-04-06 |
| JP3688735B2 (ja) | 2005-08-31 |
| EP0645139A1 (fr) | 1995-03-29 |
| KR950007848A (ko) | 1995-04-15 |
| US5447952A (en) | 1995-09-05 |
| DE69424009T2 (de) | 2000-09-14 |
| JPH07149639A (ja) | 1995-06-13 |
| AU672334B2 (en) | 1996-09-26 |
| NO943521D0 (no) | 1994-09-22 |
| RU2142274C1 (ru) | 1999-12-10 |
| CA2132509A1 (en) | 1995-03-25 |
| ATE191849T1 (de) | 2000-05-15 |
| NZ264506A (en) | 1997-09-22 |
| EP0645139B1 (fr) | 2000-04-19 |
| SG86284A1 (en) | 2002-02-19 |
| ES2145818T3 (es) | 2000-07-16 |
| TW283642B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1996-08-21 |
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