GB926472A - New halogen-pregnenes and a process for their manufacture - Google Patents
New halogen-pregnenes and a process for their manufactureInfo
- Publication number
- GB926472A GB926472A GB23349/59A GB2334959A GB926472A GB 926472 A GB926472 A GB 926472A GB 23349/59 A GB23349/59 A GB 23349/59A GB 2334959 A GB2334959 A GB 2334959A GB 926472 A GB926472 A GB 926472A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- free
- oxo
- hydrogen
- chlorine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000004043 oxo group Chemical group O=* 0.000 abstract 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 229910052801 chlorine Chemical group 0.000 abstract 3
- 239000000460 chlorine Chemical group 0.000 abstract 3
- 229910052731 fluorine Chemical group 0.000 abstract 3
- 125000001153 fluoro group Chemical group F* 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical group ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- 229960000583 acetic acid Drugs 0.000 abstract 2
- 239000012362 glacial acetic acid Substances 0.000 abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 2
- JPJALAQPGMAKDF-UHFFFAOYSA-N selenium dioxide Chemical compound O=[Se]=O JPJALAQPGMAKDF-UHFFFAOYSA-N 0.000 abstract 2
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 abstract 1
- 241000198597 Alternaria passiflorae Species 0.000 abstract 1
- 241001273385 Boeremia lycopersici Species 0.000 abstract 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 abstract 1
- 241000223218 Fusarium Species 0.000 abstract 1
- 241000427940 Fusarium solani Species 0.000 abstract 1
- 229920002527 Glycogen Polymers 0.000 abstract 1
- 206010018691 Granuloma Diseases 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 241000203720 Pimelobacter simplex Species 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 229940096919 glycogen Drugs 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 229910000040 hydrogen fluoride Inorganic materials 0.000 abstract 1
- 229910000039 hydrogen halide Inorganic materials 0.000 abstract 1
- 239000012433 hydrogen halide Substances 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH6148858A CH376105A (de) | 1958-07-07 | 1958-07-07 | Verfahren zur Herstellung neuer Halogenpregnene |
| CH6148758A CH377812A (de) | 1958-07-07 | 1958-07-07 | Verfahren zur Herstellung neuer 1,4-Pregnadiene |
| CH6936759 | 1959-02-10 | ||
| CH7158059 | 1959-04-04 | ||
| CH7157959 | 1959-04-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB926472A true GB926472A (en) | 1963-05-15 |
Family
ID=27509599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB23349/59A Expired GB926472A (en) | 1958-07-07 | 1959-07-07 | New halogen-pregnenes and a process for their manufacture |
Country Status (4)
| Country | Link |
|---|---|
| CY (1) | CY327A (enrdf_load_stackoverflow) |
| GB (1) | GB926472A (enrdf_load_stackoverflow) |
| MY (1) | MY6600003A (enrdf_load_stackoverflow) |
| SE (1) | SE220497C1 (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010136940A1 (en) | 2009-05-29 | 2010-12-02 | Pfizer Limited | Novel glucocorticoid receptor agonists |
| WO2015063408A3 (fr) * | 2013-10-28 | 2015-09-11 | Sanofi | Procede de preparation de derives steroidiens 6-alkylés et les 5,6,7,8-tetrahydronaphthalène-2(4alpha.h)-ones alkylés correspondants |
-
1959
- 1959-07-07 SE SE642059A patent/SE220497C1/sv unknown
- 1959-07-07 GB GB23349/59A patent/GB926472A/en not_active Expired
-
1965
- 1965-11-06 CY CY32765A patent/CY327A/xx unknown
-
1966
- 1966-12-31 MY MY19663A patent/MY6600003A/xx unknown
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010136940A1 (en) | 2009-05-29 | 2010-12-02 | Pfizer Limited | Novel glucocorticoid receptor agonists |
| WO2015063408A3 (fr) * | 2013-10-28 | 2015-09-11 | Sanofi | Procede de preparation de derives steroidiens 6-alkylés et les 5,6,7,8-tetrahydronaphthalène-2(4alpha.h)-ones alkylés correspondants |
| US9783569B2 (en) | 2013-10-28 | 2017-10-10 | Sanofi | Method for preparing 6-alkylated steroidal derivatives and corresponding alkylated 5,6,7,8-tetrahydronaphthalene-2(4 alpha.H)-ones |
| CN105683143B (zh) * | 2013-10-28 | 2018-09-04 | 赛诺菲 | 制备6-烷基化的甾族衍生物和相应烷基化的5,6,7,8-四氢萘-2(4αH)-酮的方法 |
| TWI655200B (zh) * | 2013-10-28 | 2019-04-01 | 賽諾菲公司 | 製備類固醇衍生物之方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| SE220497C1 (enrdf_load_stackoverflow) | 1968-05-04 |
| CY327A (en) | 1965-11-06 |
| MY6600003A (en) | 1966-12-31 |
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